Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:08 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Meniscus Tear, Tibial
Interventions: Weight-Bearing CT arthrography, Knee MRI; Diagnostic Test
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
Interventions: Montelukast, Placebo; Drug
Lead sponsor: Austin V Stone; Other
Eligibility: 25 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
Interventions: Not listed
Lead sponsor: Marquette University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
Interventions: Carbon Fiber Custom Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions: Power Knee; Device
Lead sponsor: Liberating Technologies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Holliston, Massachusetts • Austin, Texas

Conditions: Traumatic Amputation of Lower Extremity
Interventions: Not listed
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 60 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 10
States / cities: San Francisco, California • Tampa, Florida • Baltimore, Maryland + 7 more

Conditions: Surgical Site Infection
Interventions: povidone-iodine topical ointment; Drug
Lead sponsor: Loreen Herwaldt; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Atlanta, Georgia • Indianapolis, Indiana • Iowa City, Iowa + 3 more

Conditions: Ankle Fracture
Interventions: Early Weight bearing + Cam Boot, Non-Weight Bearing + Cam Boot; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 70 Years
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Femoral Fracture
Interventions: Femoral Nail GT of the T2 Alpha Femur Antegrade GT/PF Nailing System; Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 6
States / cities: Sartell, Minnesota • Reno, Nevada • New York, New York + 3 more

Conditions: ACL Tear, Arthrofibrosis, ACL Injury
Interventions: Graymont X ERIS Knee Splint, Standard Hinge Knee Brace; Device
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Musculoskeletal Injury, Anterior Cruciate Ligament Injuries
Interventions: Not listed
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 181 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Annville, Pennsylvania • Hershey, Pennsylvania

Conditions: Knee Injury
Interventions: NMES, Strength Walking, Standard Rehabilitation Protocol; Device · Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years to 50 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Andrews Air Force Base, Maryland • Bethesda, Maryland

Conditions: Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Interventions: Knowledge Translation Intervention, Educational handout; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 19 Years
Enrollment: 671 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Pelvic Fractures, Acetabular Fractures, Hip Fractures
Interventions: VAC device, Gauze dressing; Device · Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Knee Injuries and Disorders, Shoulder Disease, Shoulder Injuries
Interventions: C Scope Visualization System; Device
Lead sponsor: CIT Ortho; Industry
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Henderson, Nevada

Conditions: Knee Injuries
Interventions: Blood Flow Restriction, Standard rehabilitation; Other
Lead sponsor: Keller Army Community Hospital; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: West Point, New York • Fort Bragg, North Carolina

Conditions: Spinal Cord Injuries, Poliomyelitis, Post-polio Syndrome, Arthritis, Lower Motor Neurone Lesion
Interventions: C-brace, Stance control orthosis; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Tibia Fracture
Interventions: Post-Op Splinting, No Splinting; Procedure
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
Interventions: Accelerated Flap Coverage Surgery, Standard of Care Flap Timing; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 356 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 31
States / cities: Phoenix, Arizona • Los Angeles, California • Sacramento, California + 24 more

Conditions: Hip Injuries, Hip Dislocation, Hip Fractures
Interventions: standardized pre-conditioning treatment, Partial occlusion; Diagnostic Test
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Defect of Articular Cartilage, Knee Injuries
Interventions: Particulated Juvenile Articular Cartilage; Other
Lead sponsor: Zimmer Orthobiologics, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2021
U.S. locations: 16
States / cities: Los Angeles, California • San Deigo, California • Aurora, Colorado + 13 more

Conditions: Degenerative Lesion of Articular Cartilage of Knee
Interventions: ADSC Application, Microfracture; Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 50 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 3
States / cities: Redwood City, California • Santa Monica, California • Denver, Colorado

Conditions: Plantar Fasciitis, Flatfoot, Calcaneus Fractures
Interventions: Non-Measuring Ankle Exerciser; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury
Interventions: Myriad Matrix™ and Myriad Morcells™; Device
Lead sponsor: Aroa Biosurgery Limited; Industry
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 15
States / cities: Phoenix, Arizona • Los Angeles, California • Fort Myers, Florida + 11 more

Search by objective public record fields.

Diagnostic Value of Weight Bearing CT for Detecting Meniscal Tears

MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)

Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

Prosthetic Fit Assessment in Transtibial Amputees Secondary to Trauma

PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)

Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization

A Post-Market Clinical Evaluation of the Treatment of Femur Fractures With the Femoral Nail GT

Knee Split Comparison After ACL Reconstruction

Micro-Doppler Radar: A Gold Standard Comparison

Electromyostimulation and Strength Walking for Knee Injuries

Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer

Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures

C Scope Visualization System Prospective Study

The Effect of Blood Flow Restriction Training on Muscle Atrophy Following Knee Surgery

Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis

Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures

Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries

Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy

DeNovo NT Natural Tissue Graft Stratified Knee Study

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

Foot and Ankle Range of Motion (Stretching) Apparatus

Myriad™ Augmented Soft Tissue Reconstruction Registry