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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:13 PM EST

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Showing 361–384 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Hip Fracture Surgeries, Intertrochanteric Fracture, Femoral Hip Fracture
Interventions: Monitored Anesthesia Care (MAC), Soft Tissue Infiltration with Local Anesthetic (STILA), General Anesthesia; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 65 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 5
States / cities: Evanston, Illinois • Baltimore, Maryland • New York, New York + 2 more

Conditions: Ankle Fractures, Pilon Fracture
Interventions: Wooden block, Formal physical therapy or Home Exercise Program; Device · Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Osteoarthritis, Hip, Rheumatoid Arthritis, Non-Union Fracture, Trochanteric Fractures, Femoral Neck Fractures, Avascular Necrosis, Dislocation, Hip
Interventions: Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2038
U.S. locations: 10
States / cities: Birmingham, Alabama • Los Angeles, California • Gainesville, Florida + 7 more

Conditions: Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited, Fracture, Tibial, Fracture of Femur, Fracture Arm
Interventions: Vivigen Cellular Bone Matrix; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: Not listed
Enrollment: 250 participants
Timeline: 2021 – 2028
U.S. locations: 4
States / cities: Orlando, Florida • Jersey City, New Jersey • Durham, North Carolina + 1 more

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Graded Exposure and Mindfulness Meditation, Waitlist Control; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 14 Years to 35 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Arthroplasty, Replacement, Knee, Injuries, Knee
Interventions: Cutting Guide Technique, Haptic Feedback Technique, Four Quadrant Technique; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Anterior Cruciate Ligament Injury
Interventions: 30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine, High-frequency linear ultrasound transducer; Drug · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 16 Years to 30 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hip Fracture
Interventions: ultra-sound guide, bupivacaine, morphine; Other · Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 101 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 2
States / cities: Boston, Massachusetts • Worcester, Massachusetts

Conditions: Hip Fracture
Interventions: PUSH, Protein, Nutrition; Behavioral · Dietary Supplement
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Baltimore, Maryland • Towson, Maryland

Conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions: Exercise Group; Other
Lead sponsor: Johanna M. Hoch; Other
Eligibility: 18 Years to 35 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Knee Injuries
Interventions: Electromyographic Biofeedback, Traditional Exercise; Device · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 40 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
Interventions: pedCAT; Radiation
Lead sponsor: J L Marsh; Other
Eligibility: 18 Years to 70 Years
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Knee Pain Chronic, Knee Injuries
Interventions: Diclofenac Cream 8%, Diclofenac Gel 1%; Drug
Lead sponsor: FPR Specialty Pharmacy; Industry
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diabetic Foot Ulcer
Interventions: doxycycline, placebo gel; Drug
Lead sponsor: NanoSHIFT LLC; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Interventions: Intraosseous Morphine; Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years to 40 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Diabetic Foot Ulcer, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Neuroischemic Foot Ulcer, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer), Chronic Wound Care
Interventions: Platelet Rich Plasma; Device
Lead sponsor: Estar Medical dba Medical Technologies, LTD; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Corpus Christi, Texas

Conditions: ACL Injury
Interventions: Arthrex Internal Brace, ACL Reconstruction; Device · Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Ankle Injuries, Sprains and Strains, Joint Instability
Interventions: Hyperarch Fascia Training; Behavioral
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 20 Years to 45 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Ankle Injuries
Interventions: Antiglide Plate, Lateral Plate; Device
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 249 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 9
States / cities: Indianapolis, Indiana • Boston, Massachusetts • Grand Rapids, Michigan + 6 more

Conditions: Wound Healing
Interventions: Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser; Other · Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Rupture of Anterior Cruciate Ligament, Osteoarthritis
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 14 Years to 55 Years
Enrollment: 432 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2025
U.S. locations: 4
States / cities: St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more

Conditions: Anterior Cruciate Ligament Tear
Interventions: Sciatic Block, Femoral Block only; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Femur Fracture
Interventions: Pediatric Locking Nail; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 8 Years to 16 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 3
States / cities: Phoenix, Arizona • Orlando, Florida • Charlotte, North Carolina

Conditions: Arthralgia, Trouble Balancing
Interventions: Even-Up; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia Feasibility Trial

Simplified Post Op Rehabilitation for Ankle and Pilon Fractures

G7 Freedom Constrained Vivacit-E Liners

Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

Comparison of Three Surgical Techniques to Achieve Patella Symmetry During Resection

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

Ultrasound Guided Femoral Nerve Block

PUSH Plus Protein Pilot for Hip Fracture Patients

Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury

Effect of Electromyographic Biofeedback on Quadriceps Neuromuscular Function in Patients With Quadriceps Inhibition

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%

Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

Internal Bracing Following ACL Reconstruction

Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance

A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures

Compression and CO2 Laser for Leg Wounds

Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up

Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction

Pediatric Locking Nail for the Treatment of Femoral Fractures in Children

Even-Up to Minimize Secondary Site Pain For Ankle Fracture