Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:23 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Anterior Cruciate Ligament Tear, Pain, Postoperative, Opioid Use
Interventions: Liposomal bupivacaine, Bupivacaine Hydrochloride; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Pain, Postoperative, Femur Fracture
Interventions: Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Injury
Interventions: Whole-body Vibration, Local Muscle Vibraton, Control condition; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 39 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Distal Femur Fracture
Interventions: Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture, Koos Jr assesment on subjects with DFR of distal femur fracture; Other
Lead sponsor: University of Florida; Other
Eligibility: 55 Years to 100 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Wound
Interventions: Fibrillar collagen powder dressing; Device
Lead sponsor: Medline Industries; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pelvic Ring Fracture, Acetabular Fracture, Pelvic Fracture, Pelvic Fracture Acetabulum
Interventions: IM Implant; Device
Lead sponsor: CurvaFix, Inc.; Industry
Eligibility: Not listed
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 6
States / cities: Springfield, Illinois • Columbia, Missouri • Columbus, Ohio + 3 more

Conditions: Knee Injuries
Interventions: Control group, Intervention group; Other
Lead sponsor: Keller Army Community Hospital; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: West Point, New York

Conditions: Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Above Knee
Interventions: Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo; Device
Lead sponsor: Hanger Institute for Clinical Research and Education, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Shoulder Injuries, Hip Injuries, Foot Injury, Ankle Injuries, Knee Injuries
Interventions: Juggerknot with Broadband tape; Device
Lead sponsor: Riverpoint Medical; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Hyattsville, Maryland

Conditions: Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
Interventions: Low cost lower limb prosthetic socket; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 95 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anterior Cruciate Ligament Injuries
Interventions: The BEAR® Implant; Device
Lead sponsor: Miach Orthopaedics; Industry
Eligibility: 14 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 8
States / cities: Redwood City, California • Steamboat Springs, Colorado • Orlando, Florida + 5 more

Conditions: Hip Fracture
Interventions: Control: Saline, Tranexamic Acid; Drug
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Bryn Mawr, Pennsylvania

Conditions: Trauma Injury
Interventions: Lower Extremity Amputation; Procedure
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Opiate Sparing, Opiate Based; Drug
Lead sponsor: Campbell Clinic; Other
Eligibility: 14 Years to 85 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 3
States / cities: Skokie, Illinois • Cincinnati, Ohio • Memphis, Tennessee

Conditions: Metatarsal Stress Fracture, Stress Fracture of Tibia
Interventions: Photobiomodulation Therapy with Standard Physical Therapy, Sham Photobiomodulation Therapy with Standard Physical Therapy; Device · Other
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 17 Years to 64 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sprain of Ankle
Interventions: Platelet rich plasma injection, Placebo Comparator: Placebo/Standard of Care; Procedure
Lead sponsor: Albert Einstein Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Knee Injury
Interventions: Placement of allograft CR Plug in primary injury site; Procedure
Lead sponsor: RTI Surgical; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 3
States / cities: Los Angeles, California • Denver, Colorado • Indianapolis, Indiana

Conditions: Femoral Neck Fractures
Interventions: Hip Hemiarthroplasty; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 65 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Trauma, Patella Fracture, Knee Cap, Knee Cap Injury, Knee Discomfort, Knee Deformity
Interventions: Variable Angle LCP Patella Plating System, Traditional Fixation; Device
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years to 74 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Lower Limb Injury
Interventions: Powered hip exoskeleton; Device
Lead sponsor: Georgia Institute of Technology; Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Complete Tear, Knee, Anterior Cruciate Ligament, Rupture of Anterior Cruciate Ligament
Interventions: ACL Reconstruction: Anterior Tunnel, ACL Reconstruction: Posterior Tunnel; Procedure
Lead sponsor: University of Virginia; Other
Eligibility: 16 Years to 50 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Tibial Fractures
Interventions: recombinant bone morphogenetic protein 2, Autogenous iliac crest bone graft; Device · Procedure
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 13
States / cities: San Francisco, California • Denver, Colorado • Tampa, Florida + 10 more

Conditions: Spinal Cord Injury
Interventions: Transcutaneous Electrical Spinal Cord Stimulation; Device
Lead sponsor: NeuroEnabling Technologies, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

Stair Biomechanics and Vibration Study After ACLR

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

An Evaluation of a Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds

Curvafix® Intramedullary System for Fixation of Pelvic and Acetabular Fractures, A Post Market Evaluation

A Randomized Control Trial: Returning to Run After Injury

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

JuggerKnot With Broadband PMCF Study

Low Cost Socket for Lower Limb Amputees

A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)

Effects of Tranexamic Acid on Blood Loss and Transfusion Requirement Following Hip Fracture

ICG Fluorescence Imaging in Lower Extremity Amputation Patients

Reduce Opiate Exposure With ACL Surgery

Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting

Influence of Socket Volume on Prosthesis Performance

Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department

Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.

Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population

DePuy Synthes Variable Angle LCP Patella Plating System Study

Powered Hip Exoskeleton Assistance Study

Tibial Tunnel Placement for ACL Reconstruction

rhBMP-2 Versus Autograft in Critical Size Tibial Defects

Transcutaneous Electrical Spinal Cord Stimulation for Lower Limbs