Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:31 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Ankle Sprain
Interventions: HKT-500 Ketoprofen Topical Patch, Placebo Patch; Drug · Other
Lead sponsor: Hisamitsu Pharmaceutical Co., Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 30
States / cities: Birmingham, Alabama • Montgomery, Alabama • Anaheim, California + 26 more

Conditions: Leg Injuries
Interventions: Not listed
Lead sponsor: Mitchell Selhorst; Other
Eligibility: 13 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Westerville, Ohio

Conditions: Anterior Cruciate Ligament Injury
Interventions: Virtual Reality Mindfulness Meditation, Virtual Reality Sham; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 14 Years to 25 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Hip Fracture
Interventions: Femoral Nerve Catheterization, Intravenous Opioids; Procedure
Lead sponsor: Leslie Thomas; Other
Eligibility: 50 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2022
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Arthrofibrosis of Knee
Interventions: Werewolf FLOW 50, Control; Device · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 18 Years
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Aurora, Colorado • Broomfield, Colorado • Highlands Ranch, Colorado

Conditions: Foot Injuries, Ankle Injuries
Interventions: New durable medical equipment (DME) walking boot, Re-used durable medical equipment (DME) walking boot; Device
Lead sponsor: University of Utah; Other
Eligibility: 1 Year to 17 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury
Interventions: Botulinum toxin type A; Biological
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 15
States / cities: Scottsdale, Arizona • Downey, California • Oxnard, California + 12 more

Conditions: Amputation, Diabetes Complications, Leg Injuries, Traumatic Amputation
Interventions: Pe-Lite and sleeve suspension socket, Total Surface bearing a socket with a sleeve suspension but without suction, Total surface bearing suction socket with a pin lock suspension, Total surface bearing suction socket with a sleeve suspension, Vacuum-assisted socket system (Harmony System, Otto Bock); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Knee Injuries
Interventions: Spinal Surgery, Verasense Knee System device; Procedure · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 50 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Tibial Fractures
Interventions: Short leg cast, No Immobilization; Procedure
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 1 Year to 5 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Ankle and or Hindfoot Injury
Interventions: Dry Needling; Other
Lead sponsor: Regis University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Anterior Cruciate Ligament Rupture
Interventions: Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 14 Years to 65 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Lower Limb Amputation Above Knee (Injury), Congenital Amputation of Lower Limb, Lower Limb Amputation Knee
Interventions: Kenevo or C-Leg 4, Non microprocessor controlled knee (NMPK); Device
Lead sponsor: Otto Bock Healthcare Products GmbH; Industry
Eligibility: 65 Years and older
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 90
States / cities: Dothan, Alabama • Gilbert, Arizona • Phoenix, Arizona + 85 more

Conditions: Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
Interventions: Questionnaire; Other
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Shin Splint, Running-related Injury
Interventions: In-Field Gait-Training, Home Exercise; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: ACL Tear
Interventions: Safe Return to Play Following ACL Reconstruction Checklist; Diagnostic Test
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 15 Years to 35 Years
Enrollment: 222 participants
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino, Adolescent
Interventions: Educational program and patient navigator; Behavioral
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 14 Years to 18 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Internal focus of attention feedback, Visual internal focus of attention feedback, Auditory external focus of attention feedback; Other
Lead sponsor: University of North Carolina, Charlotte; Other
Eligibility: 18 Years to 35 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Musculoskeletal Injury
Interventions: Shock wave, Radial pressure waves, Electromagnetic transduction therapy (EMTT); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2035
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Anterior Cruciate Ligament Rupture
Interventions: IPACK block; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Femur Fracture
Interventions: Spica casting; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 2 Years to 6 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Osteoarthritis (OA) of the Hip, Avascular Necrosis of Bone of Hip, Protrusio Acetabuli, Traumatic Arthropathy-Hip, Slipped Capital Femoral Epiphyses, Fused Hip, Fracture of Pelvis, Diastrophic Variant
Interventions: Vivacit-E Elevated Liners; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: South Bend, Indiana

Conditions: ACL Tear
Interventions: Mental Skills Coaching; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 8 Years to 25 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Waltham, Massachusetts

Conditions: Ankle Fractures
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Charlotte, North Carolina

Search by objective public record fields.

HKT-500 in Adult Patients With Ankle Sprain

Smart Phone as a Screening and Evaluation Tool to Identify Knee Valgus During Dynamic Activities

Virtual Reality Mindfulness Meditation After ACL Reconstruction

A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients

Werewolf Flow 50 During ACL Reconstruction

The Safety of Reusing Walking Boot Components for Patients Recovering From Acute Foot and Ankle Injuries

Dysport® Adult Lower Limb Spasticity Follow-on Study

Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking

Evaluation of Patient Reported Outcomes (PRO) After Total Knee Arthroplasty (TKA) Under Spinal Anesthesia

Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial

The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot

Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction

Assessing Outcomes With Microprocessor Knee Utilization in a K2 Population

Women's-Specific Footwear With Prosthetic Feet

Gait-Training Using Wearable Sensors

Safe Return to Play After ACL Reconstruction

Reducing Disparities in Knee Arthroscopy for Adolescents

External Focus of Attention Feedback to Reduce Risk of Non-contact ACL Injury

Focused Shockwave (ESWT), Radial Pressure Waves (EPAT), And Electromagnetic Transduction Therapy (EMTT) For Lower Extremity Musculoskeletal Injuries

Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:

Spica Casting in Pediatric Femur Fractures: Study of Single Leg Versus Double Leg Spica Casts

MDR Vivacit-E Elevated Study

Readiness Outcomes Affecting Return to Sport 2.0: An Intervention Feasibility & Pilot Study

Ankle Fracture vs Ankle Fracture-Dislocation