Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Knee Injuries, Knee Osteoarthritis, Knee Arthritis
Interventions: B-FREE; Other
Lead sponsor: Michigan Technological University; Other
Eligibility: 40 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Houghton, Michigan

Conditions: Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
Interventions: AMES Treatment; Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Atlanta, Georgia • Portland, Oregon

Conditions: Proximal Femur Fractures
Interventions: ORIF; Procedure
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: Not listed
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteoporotic Fractures
Interventions: Teriparatide Prefilled Syringe, Placebo; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 65 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament Deficiency
Interventions: Ossur Rebound ACL Brace; Device
Lead sponsor: Steadman Philippon Research Institute; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Vail, Colorado

Conditions: Neural Inhibition, Injuries, Ankle
Interventions: Kinesiotaping; Device
Lead sponsor: Oregon State University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Corvallis, Oregon

Conditions: Tibial Fractures
Interventions: Suprapatellar approach, Infrapatellar approach; Procedure
Lead sponsor: Florida Orthopaedic Institute; Network
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Tampa, Florida

Conditions: Hip Disease, Hip Fractures, Hip Injuries, Hip Arthritis, Hip Pain Chronic
Interventions: M/L Taper with Kinectiv Technology Stems and Necks; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Rupture of Anterior Cruciate Ligament
Interventions: Bupivacaine, Preservative free normal saline; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions: Custom Carbon Fiber Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture
Interventions: Antibiotic coated intramedullary Nail, Standard Intramedullary Nail; Drug · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 15
States / cities: Gainesville, Florida • Temple Terrace, Florida • Macon, Georgia + 12 more

Conditions: Distal Femur Fracture
Interventions: Carbo-fix Lateral Plate Device, Standard Plate-Nail Construct; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Musculoskeletal Injury
Interventions: Self-Directed Exercise Program, Clinic-Based Physical; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 65 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Charlotte, North Carolina • Greenville, South Carolina

Conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions: Autologous Bone Marrow Derived Mesenchymal Stem Cells, Sham incision; Device · Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pilon Fracture of Tibia
Interventions: Not listed
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: 18 Years and older
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 4
States / cities: Indianapolis, Indiana • Saint Paul, Minnesota • Jackson, Mississippi + 1 more

Conditions: Trauma Injury
Interventions: Lower Extremity Surgery; Procedure
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Tibia Fracture, Humerus Fracture, Femoral Fracture, Long Bone Segmental Defect
Interventions: TRUMATCH Graft Cage; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions: Exparel, Peripheral Nerve Block; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Knee Injuries
Interventions: Physical Therapy; Other
Lead sponsor: Twin Cities Orthopedics; Other
Eligibility: 14 Years to 59 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Edina, Minnesota

Conditions: Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
Interventions: Video Education, Usual Care Group; Behavioral
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Spasticity
Interventions: Phase 2; Low Dose MYOBLOC (15,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 2; Placebo, Phase 3; MYOBLOC, Phase 3; Placebo; Drug
Lead sponsor: Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 4
States / cities: Downey, California • Boise, Idaho • Port Royal, South Carolina + 1 more

Conditions: Distal Femur Fracture
Interventions: Device - Prism Medical FGA-700 Bariatric Floor Lift; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Ankle Injuries
Interventions: Physical Rehabilitation; Other
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years to 45 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Anterior Cruciate Ligament Injury
Interventions: DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System; Device · Other
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 30 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

Blood-Flow Restriction Exercise Following a Knee Replacement

Spinal Cord Injury Leg Rehabilitation

Development and Validation of Intraoperative Image-quality Criteria

PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial

Dynamic ACL Brace: In Vivo Kinematics

The Effects of Kinesio Tape® on Arthrogenic Muscle Inhibition and Rate of Torque Development

Suprapatellar Versus Infrapatellar Nailing in Tibial Fractures: A Pilot Study

MDR - M/L Taper With Kinectiv Technology Stems and Necks

Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing ACL Reconstruction

Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures

Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures

Biologic Augmentation With Mesenchymal Stem Cells in Patients Undergoing Anterior Cruciate Ligament Reconstruction

Pilon Fracture Reduction and Functional Outcome

SFDI in High Energy Lower Extremity Fracture

A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction

Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity

Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture

Neurophysiology of Ankle Instability

Blood Flow Restriction to Improve Muscle Strength After ACL Injury