Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures, Ankle Fractures, Tibial Fractures
Interventions: Decision tool, Standard treatment information; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 2,310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Medial Tibial Stress Syndrome
Interventions: Acupuncture, Home Exercise Program; Other
Lead sponsor: Eglin AFB Regional Hospital; Federal
Eligibility: 18 Years and older
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Eglin Air Force Base, Florida

Conditions: Hip Fractures, Delirium
Interventions: Deeper sedation, Moderate sedation; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 65 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hypovitaminosis D
Interventions: Cholecalciferol, Placebo; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tibial Fractures
Interventions: Force monitoring of external fixator struts; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Lower Extremity Surgery, Surgical Site Infection, Bacterial Colonization, Surgical Antiseptic
Interventions: Chloraprep; Drug
Lead sponsor: Sanford Health; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Anterior Cruciate Ligament Injury, Knee Injury
Interventions: Standard Plyometric Training, Plyometric Training with BWS; Procedure
Lead sponsor: University of Montana; Other
Eligibility: 12 Years to 35 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Missoula, Montana

Conditions: Syndesmotic Injuries
Interventions: Arthrex Tightrope, Synthes Fibulink; Device
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Foot Injuries and Disorders
Interventions: Structure Sensor; Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure, Trauma
Interventions: Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection; Drug · Other
Lead sponsor: The Stone Research Foundation for Sports Medicine and Arthritis; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring, Fragility Fracture, Internal Fixation, Nonoperative Care
Interventions: Early Internal Fixation, Nonoperative Care with Early Rehabilitation; Procedure · Other
Lead sponsor: University of Southern California; Other
Eligibility: 60 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 12
States / cities: Phoenix, Arizona • Los Angeles, California • Sacramento, California + 7 more

Conditions: Knee Injuries, Joint Surface Knee Lesions
Interventions: Marketed Product - MP01, Other Surgical Treatments; Device · Procedure
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2034
U.S. locations: 6
States / cities: Parker, Colorado • Washington D.C., District of Columbia • Indianapolis, Indiana + 3 more

Conditions: Femoral Fractures
Interventions: Standard Reaming, Reaming/Irrigating/Aspirating; Procedure
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years to 85 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 9
States / cities: Indianapolis, Indiana • Burlington, Massachusetts • Columbia, Missouri + 6 more

Conditions: Ankle Fracture
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 90 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Spinal Cord Injuries
Interventions: Motor-assisted arms and legs cycling; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ankle Fracture
Interventions: Repair Deltoid Tendon, Ankle Fracture Without Deltoid Tendon Repair; Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Muscle Wasting (Atrophy) After Hip Fracture Surgery
Interventions: bimagrumab, placebo; Drug · Other
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 60 Years and older
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 6
States / cities: Phoenix, Arizona • El Cajon, California • Denver, Colorado + 3 more

Conditions: Peripheral Arterial Disease, Intermittent Claudication
Interventions: Home-based leg heat therapy; Device
Lead sponsor: Purdue University; Other
Eligibility: 60 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: Adjustable socket; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Ankle Sprains, Ankle Injuries and Disorders
Interventions: Walking, Rucking, Running; Other
Lead sponsor: Danielle Torp; Other
Eligibility: 18 Years to 45 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Lexington, Kentucky • Charlotte, North Carolina

Conditions: Femoral Neck Fractures, Intertrochanteric Fractures
Interventions: PENG, FICB; Procedure
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Pelvic Fracture
Interventions: Pelvic Binder Radiography; Diagnostic Test
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
Interventions: Auto Adjusting Prosthesis; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Anterior Cruciate Ligament Injury, Knee Injuries
Interventions: Surgical reconstruction of the ACL; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2015
U.S. locations: 1
States / cities: New York, New York

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Conjoint Analysis of Patient Preferences in Joint Interventions

Acupuncture for Medial Tibial Stress Syndrome in the Primary Care Setting

Post-Operative Delirium in Elderly Surgical Patients

Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients

Mobile Monitoring of Fracture Healing

Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction

Randomized Controlled Trial Comparing Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry

Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study

Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

Knee Cartilage Repair Registry

Standard Reaming Versus Reaming/Irrigating/Aspirating for Intramedullary Nailing of Femoral Shaft Fractures

Insole Sensor to Determine Optimal Limb Loading in the Rehabilitation of Ankle Fractures

Arm and Leg Cycling for Accelerated Recovery From SCI

Is Deltoid Ligament Repair for Ankle Fracture Necessary?

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease

Auto Control of Volume Management for Limb Loss

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

PENG vs FICB for Hip Fracture in ED Patients

Stress Radiography for Pelvic Ring Injuries

An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation

Bone Tunnel Widening Following ACL Reconstruction