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Showing 601–624 of 803 matching trials from the live ClinicalTrials.gov search.
Conditions
Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg, Fracture
Interventions
Bupivacaine, Exparel + Bupivacaine
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Results available

Gait Modification Treatments for Knee Pathology

NCT03116230
Conditions
Knee Injuries, Knee Osteoarthritis
Interventions
Cutaneous Stimulation, Knee Sleeve
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Conditions
Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
Interventions
AlterG anti-gravity treadmill
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
10
States / cities
San Diego, California • San Francisco, California • Lexington, Kentucky + 7 more
Conditions
Ankle Sprain
Interventions
Jump Stretch
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
8 Years to 21 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Hip Fractures
Interventions
Regional Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
1,848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
38
States / cities
Birmingham, Alabama • Sacramento, California • Hartford, Connecticut + 31 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Auto Adjusting Dynamic AFO

NCT04623853
Conditions
Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
Interventions
Variable Stiffness AFO
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Conditions
ACL Tear, Post Operative Pain
Interventions
Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap
Device · Drug
Lead sponsor
Matthew Varacallo
Other
Eligibility
15 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
DuBois, Pennsylvania
Conditions
Lower Limb Trauma
Interventions
Promis Physical Function Questionnaire, L Test, Narrowing Beam Walking Test, PEQ-A
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Femoral Fractures, Tibial Fractures
Interventions
RIA bone graft, Surgery without bone graft
Procedure
Lead sponsor
Florida Orthopaedic Institute
Network
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Tampa, Florida
Conditions
Osteoarthritis, Rheumatoid Arthritis, Femoral Fracture, Correction of a Functional Deformity, Avascular Necrosis
Interventions
Encore Linear™ Hip System
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Vero Beach, Florida
Conditions
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Interventions
Platelet Rich Plasma, Saline Placebo
Biological · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Accepts healthy volunteers

Intramedullary Nailing of Tibia Fractures

NCT01797640
Conditions
Tibial Fractures, Malleolar Fractures
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 95 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Femoral Fracture
Interventions
RFN-Advanced Retrograde Femoral Nailing System
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Diego, California
Conditions
Unstable Pelvic Ring Fracture, Unstable Acetabulum Fracture, Femur Fracture
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
16 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar, Ankle Fracture - Medial Malleolus, Maisonneuve's Fracture, Syndesmotic Injuries, Fibula Fracture
Interventions
Tourniquet
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Diabetic Foot Ulcers (DFUs), Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
Miro3D Wound Matrix, Standard of Care (SOC)
Device · Other
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Coconut Creek, Florida • Tamarac, Florida • New York, New York
Conditions
Complications; Arthroplasty, Knee Injuries
Interventions
Bupivacaine, Preservative free normal saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Diabetic Foot, Lower Extremity Wound
Interventions
Matrion, Conventional Care Wound Management
Other
Lead sponsor
LifeNet Health
Industry
Eligibility
21 Years to 80 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Tucson, Arizona • Carmichael, California • Fresno, California + 5 more
Conditions
Meniscus; Detachment, Current Injury
Interventions
Standard of Care Rehabilitation, Experimental Strength Training
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Balance Training With tDCS for CAI

NCT04390048
Conditions
Ankle Injuries and Disorders
Interventions
Anodal tDCS, Sham tDCS
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Coral Gables, Florida
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction

NCT03818932
Conditions
Anterior Cruciate Ligament Injury
Interventions
Celecoxib, Hydrocodone-Acetaminophen, Ketorolac, Gabapentin, Acetaminophen, Diazepam
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Completed Phase 3 Interventional Results available

Dysport® Adult Lower Limb Spasticity Study

NCT01249404
Conditions
Leg Spasticity
Interventions
Botulinum toxin type A, Placebo
Biological · Drug
Lead sponsor
Ipsen
Industry
Eligibility
18 Years to 80 Years
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
17
States / cities
Scottsdale, Arizona • Downey, California • Oxnard, California + 12 more
Conditions
Anterior Cruciate Ligament, Injury
Interventions
ACL reconstruction
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Orthopedic Disorder, Anterior Cruciate Ligament Injuries
Interventions
Quad tendon, BTB
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama