Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:57 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 625–648 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Spinal Cord Injury
Interventions: Trained SCI Knee or Trained SCI Hip; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Limb Salvage, Braces, Lower Extremity
Interventions: Advanced orthotic brace, Conventional orthotic brace; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: New York, New York • Houston, Texas

Conditions: Injury of Anterior Cruciate Ligament
Interventions: bupivacaine, continuous perineural infusion catheter; Drug · Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 14 Years to 18 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Injuries, Knee
Interventions: Single Portal Knee Arthroscopy, Two Portal Knee Arthroscopy; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: ACL Injury, Anterior Cruciate Ligament Injuries
Interventions: Video-Based Intervention, Classroom-Based Intervention; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 15 Years to 65 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Femur Fracture
Interventions: Antegrade Intramedullary Nail, Trigen Trochanteric Femoral Nail; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Wound Infection, Fractures, Open, Surgical Site Infection
Interventions: Tobramycin Injection; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 3
States / cities: Lexington, Kentucky • Boston, Massachusetts • Nashville, Tennessee

Conditions: Intertrochanteric Fractures, Femoral Fracture, Femoral Neck Fractures
Interventions: Artemis Proximal Femoral Nail (PFN) implant; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Ankle Sprains, Motor Coordination or Function; Developmental Disorder
Interventions: Self-Hypnosis, Ankle Education; Behavioral
Lead sponsor: Ohio University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
Interventions: Surgery; Procedure
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 3
States / cities: New York, New York • Nashville, Tennessee

Conditions: Knee Injuries, Anterior Cruciate Ligament Injuries
Interventions: Blood Flow Restriction Therapy, Standard Postoperative Physical Therapy; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Non-Healing Ulcer of Skin, Non-healing Wound, Lower Extremity Wound
Interventions: Microvessel Ultrasound Examination, Skin Biopsy; Diagnostic Test · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Lower Extremity Fracture, Surgical Fracture Repair, Orthopaedic Trauma, Orthogeriatric Fractures
Interventions: Local anesthesia injections; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Spinal Cord Injuries, Spinal Cord Diseases, Central Nervous System Diseases, Nervous System Diseases, Trauma, Nervous System, Wounds and Injuries
Interventions: Transcutaneous spinal stimulation, Epidural spinal stimulation; Device
Lead sponsor: University of Washington; Other
Eligibility: 21 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Anterior Cruciate Ligament Injury
Interventions: Neuromuscular Electrical Stimulation (NMES), Eccentric Exercise (ECC), Neuromuscular Electrical Stimulation (NMES) placebo, Eccentric Exercise (ECC) placebo; Device · Other
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 45 Years
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 2
States / cities: Ann Arbor, Michigan

Conditions: Syndesmotic Injuries
Interventions: Arthrex InternalBrace; Device
Lead sponsor: St. Clair Orthopaedics; Other
Eligibility: 18 Years to 105 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Saint Clair Shores, Michigan

Conditions: ACL Injury
Interventions: OOC; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg, Wound of Knee
Interventions: Nanofat-seeded biological scaffold on surgical defect; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pelvic Fracture
Interventions: Application of circumferential pelvic compression (CPC) device; Procedure
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 64 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 11
States / cities: Miami, Florida • Indianapolis, Indiana • Baltimore, Maryland + 8 more

Conditions: Meniscus Tears, Loose Bodies, Articular Osteoarthritis, Articular or Capsular Trauma
Interventions: VisionScope Imaging (VSI) Exam; Procedure
Lead sponsor: VisionScope Technologies; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 7
States / cities: Los Angeles, California • Redwood City, California • Santa Monica, California + 4 more

Conditions: Pain, Postoperative
Interventions: Methadone, Morphine; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 50 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
Interventions: Rocuronium, Sugammadex, Normal saline; Drug
Lead sponsor: Loyola University; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: ACL Injury
Interventions: HMB, Placebo; Dietary Supplement
Lead sponsor: Metabolic Technologies Inc.; Industry
Eligibility: 18 Years to 49 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Ames, Iowa

Conditions: Lower Limb Injury
Interventions: Placebos, Dexamethasone Sodium Phosphate; Drug
Lead sponsor: University of Arizona; Other
Eligibility: 5 Years to 25 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Tucson, Arizona

Search by objective public record fields.

Training of Eccentric Lower Extremity Function After SCI

The IM ABLE Study: A Study of Warriors & Veterans Following Neuromusculoskeletal Injury of the Lower Limb

Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair

Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques

Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes

Intramedullary Nailing of the Femur:Trochanteric vs Piriformis Starting Portals

Tobramycin Injection to Prevent Infection in Open Fractures

Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures

Project Hypnos: The Impact of a Brief Hypnosis Intervention on Single-limb Dynamic Balance in People With Chronic Ankle Instability

Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

Effects of Blood Flow Restriction (BFR) Therapy on ACL Graft Maturation

A Study to Evaluate Microvessel Ultrasound Imaging of Wound Healing in Patients With Chronic Ulcers

Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults

Comparison of Transcutaneous and Epidural Spinal Stimulation for Improving Function

MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation

Treatment of Syndesmotic Disruption With Anatomic Distal Tibiofibular Ligament Augmentation

Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound

Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects

A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring

Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee

Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

Effects of HMB Supplementation on Recovery Following ACL Surgery

IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery