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Showing 49–72 of 803 matching trials from the live ClinicalTrials.gov search.
Not listed Not applicable Interventional Accepts healthy volunteers

Mechanical Perturbation Training for ACL Injury Prevention

NCT03080402
Conditions
Anterior Cruciate Ligament Injury, ACL
Interventions
Mechanical Perturbation Training
Device
Lead sponsor
University of Delaware
Other
Eligibility
15 Years to 30 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Gait
Interventions
None- Observational Study
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
244 participants
Timeline
2019 – 2024
U.S. locations
10
States / cities
Lexington, Kentucky • Baltimore, Maryland • Bethesda, Maryland + 7 more
Conditions
Hip Fracture, Myocardial Ischemia, Inflammation
Interventions
Atorvastatin, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
65 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Therapy in Lower Limb Extensor Injuries

NCT04149977
Conditions
Lower Limb Injury
Interventions
Physical Therapy with pressure cuff, Physical Therapy with placebo pressure cuff
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Lower Extremity Injuries
Interventions
Visual Feedback
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Everett, Washington
Conditions
Knee Injury
Interventions
Dexamethasone, Ropivacaine
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 19 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Fracture, Infection, Depression, Gait Instability, Debility
Interventions
Home Visit
Other
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Staten Island, New York
Conditions
Tibial Fractures
Interventions
3D printed plastic model prototype, 3D CT scan, Plain film radiographs
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Falls Church, Virginia
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Menstrual Cycle-Synced Neuromuscular Training

NCT06983184
Conditions
ACL Injuries
Interventions
MC-synced NTP, Blinded NTP
Other
Lead sponsor
Sophia Ulman
Other
Eligibility
13 Years to 19 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Frisco, Texas
Conditions
Ankle Fractures
Interventions
VPOD Wireless Tens Unit, Physical Therapy, Biodex
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Knee Injury
Interventions
Anakinra
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 30 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Knee Injuries, Cartilage, Articular, Gait
Interventions
Real-time gait biofeedback, Sham real-time gait biofeedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Compartment Syndrome Traumatic Lower Extremity
Interventions
Intramuscular administration of autologous BM-MNCs
Biological
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain, Toe-walking, Tendonitis of Foot, Apophysitis; Juvenile
Interventions
Waterproof padding, Non-waterproof padding
Device
Lead sponsor
West Virginia University
Other
Eligibility
5 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Bridge-Enhanced ACL Repair vs ACL Reconstruction

NCT02664545
Conditions
Anterior Cruciate Ligament Tear
Interventions
BEAR Scaffold, Tendon Graft
Device · Procedure
Lead sponsor
Miach Orthopaedics
Industry
Eligibility
14 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of Topical Wound Oxygen (two2) Therapy

NCT00871312
Conditions
Diabetic Ulcer
Interventions
Topical wound oxygen therapy, Topical wound oxygen Placebo
Device
Lead sponsor
AOTI Ltd.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Buffalo, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes

NCT01034527
Conditions
ACL Injury
Interventions
Neuromuscular Training
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 19 Years · Female only
Enrollment
593 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Neuromuscular Warm-up on Injuries in Female Athletes

NCT01092286
Conditions
Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
Interventions
neuromuscular warm-up
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
14 Years to 80 Years
Enrollment
1,653 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Enrolling by invitation Not applicable Interventional

Ankle Fracture Tourniquet Utilization

NCT06863688
Conditions
Ankle Fracture
Interventions
Tourniquet, No Tourniquet
Device · Other
Lead sponsor
Alex Demers
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures
Interventions
Vancomycin Hydrochloride, Gentamicin, Standard Intramedullary Nail
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
12
States / cities
Los Angeles, California • Macon, Georgia • Chicago, Illinois + 9 more
Conditions
Hip Fractures, Intertrochanteric Fractures
Interventions
Tranexamic Acid (TXA), Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Knee Injuries
Interventions
PCL, posterolateral reconstruction
Procedure
Lead sponsor
Sue Barber-Westin
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
Interventions
Manual Therapy Group, Control Group
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hip Fracture, Depression
Interventions
Enhanced acute medical rehabilitation, Treatment as usual
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
St Louis, Missouri