Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:42 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Fracture; Pelvic, Insufficiency Fractures, Fragility Fracture, Sacroiliac; Fusion, Sacroiliac Joint Disruption, Sacroiliac Joint Dysfunction
Interventions: iFuse TORQ TNT Implant System; Device
Lead sponsor: SI-BONE, Inc.; Industry
Eligibility: 60 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Edina, Minnesota • Rochester, Minnesota • Wyomissing, Pennsylvania

Conditions: Wound Heal
Interventions: Participants in this group will receive the experimental APIS Biomaterial on the Head., Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities., Standard Secondary Intention Healing on the Head, Standard Secondary Intention Healing on the Lower Extremities; Device · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Chronic Ankle Instability, CAI, Ankle Sprain, Healthy
Interventions: Cobra Ankle Arthrometer; Device
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 40 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Femur Fracture
Interventions: Single Distal Femur Implant, Dual Distal Femur Implant; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 60 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: ACL, ACL Injury
Interventions: Healthy Minds Program (HMP) App; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 16 Years to 40 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Surgical Wound Healing, Lower Extremity, Revascularization, Incision
Interventions: EPIFLO; Device
Lead sponsor: Neogenix, LLC dba Ogenix; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetic Foot Ulcer, Lower Extremity Wound
Interventions: DermACELL AWM; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Fresno, California • Rocky Mount, North Carolina

Conditions: Ankle Injuries, Foot Injuries
Interventions: OFAR; Procedure
Lead sponsor: Lehigh Valley Hospital; Other
Eligibility: 16 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Allentown, Pennsylvania

Conditions: Athletic Injuries, Sprains and Strains, Wounds and Injuries, Knee Injuries
Interventions: Activity Training with Feedback; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Stanford, California

Conditions: Hip Fractures, Hip Injuries
Interventions: 2 weeks of partial weight bearing on crutches, 4 weeks of partial weight bearing on crutches; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Femur Fracture
Interventions: 0.5% ropivacaine, Normal Saline; Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Ankle Sprains
Interventions: SMART Intervention, Standard of Care Intervention; Other
Lead sponsor: Phillip Gribble; Other
Eligibility: 18 Years to 44 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 2
States / cities: Lexington, Kentucky • Chapel Hill, North Carolina

Conditions: Hip Fractures, Femoral Shaft Fractures
Interventions: Standard of Care, Distal targeting device technique of distal screw placement; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Anterior Cruciate Ligament Tear
Interventions: Blood flow restriction; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Knee Pain, Hip Pain, Ankle Pain, Lumbopelvic Pain
Interventions: lumbosacral joint manipulation, lumbar passive range of motion, No active intervention; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 50 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Foot Ulcer, Diabetic Foot
Interventions: Collagenase ointment, Modified Contact Cast System; Drug · Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Infection
Interventions: VeraFlo with Prontosan, V.A.C Ulta System; Drug · Device
Lead sponsor: Brett Crist; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Knee Injuries
Interventions: OMS103HP, Vehicle; Drug
Lead sponsor: Omeros Corporation; Industry
Eligibility: 15 Years to 65 Years
Enrollment: 326 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 15
States / cities: Encinitas, California • Denver, Colorado • Englewood, Colorado + 12 more

Conditions: Arthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, Meditation, Knee Osteoarthritis, Knee Disease, Knee Injuries, Opioid Use, Opioid Dependence, Opioid Use Disorder
Interventions: Mindful meditation; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 89 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hip Fractures
Interventions: Accelerated medical clearance and surgery; Other
Lead sponsor: McMaster University; Other
Eligibility: 45 Years and older
Enrollment: 3,001 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 5
States / cities: San Jose, California • Baltimore, Maryland • Burlington, Massachusetts + 2 more

Conditions: Leg Injuries
Interventions: neuromuscular exercises; Other
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 10 Years to 14 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Rupture of Anterior Cruciate Ligament
Interventions: Not listed
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 12 Years to 35 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Ulcers
Interventions: NIRS imaging in addition to SOC; Device
Lead sponsor: Kent Imaging Inc; Industry
Eligibility: 18 Years and older
Enrollment: 221 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: New Braunfels, Texas • San Antonio, Texas • San Marcos, Texas

Conditions: Spinal Cord Injury
Interventions: FES Cycle, ES therapy, Passive (Motor Assist) Cycle; Device
Lead sponsor: Shriners Hospitals for Children; Other
Eligibility: 5 Years to 15 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 2
States / cities: Baltimore, Maryland • Philadelphia, Pennsylvania

Search by objective public record fields.

Real World Evidence of SI-BONE's iFuse TORQ TNT Advancing Treatment of Pelvic Ring Fractures

Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities

Validation of a Portable Ankle Arthrometer

Dual Implant Versus Single Implant Distal End of Femur

Mindfulness and ACL Surgery

Oxygen for Vascular Incisional Healing

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

Triage-Based Application of OFAR on the Number of Radiographs Ordered

The Design and Evaluation of an Active Intervention for the Prevention of Non-contact ACL Injury

Crutch Use After Arthroscopic Hip Surgery

Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

Trial of a Distal Targeting System for Cephalomedullary Nails as Part of Surgical Repair of Hip and Femoral Shaft Fractures

Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation

Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response

EZCast-DFU Study With Portal for Application of Topical Medications

VeraFlo With Prontosan® and Wound and Fracture Healing.

Efficacy and Safety of OMS103HP in Patients Undergoing Autograft Anterior Cruciate Ligament (ACL) Reconstruction

Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement

HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial

Neuromuscular Training to Reduce Sports Injuries Among Children and Adolescents

Anterior Cruciate Ligament (ACL) Reconstruction- Bioabsorbable Screw

Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers

Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)