Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:26 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Femoral Fracture
Interventions: Gamma4 Nailing System; Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 5
States / cities: Royal Oak, Michigan • Cleveland, Ohio • San Antonio, Texas + 2 more

Conditions: Knee Injuries
Interventions: MRI; Procedure
Lead sponsor: Twin Cities Orthopedics; Other
Eligibility: 14 Years to 70 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Edina, Minnesota

Conditions: Ankle Fractures
Interventions: Regional anesthesia group, Local multimodal analgesia group; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 80 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Wound Healing, Mohs Micrographic Surgery
Interventions: Timolol Maleate Solution, Standard of Care; Drug · Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injuries, Spasticity, Spasm, Muscle Spasticity, Muscle Hypertonia, Muscle Spasm
Interventions: Transcutaneous spinal stimulation at 30 Hz, Transcutaneous spinal stimulation at 75 Hz, Tizanidine, Baclofen, Placebo; Other · Drug
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Jackson, Mississippi

Conditions: Venous Leg Ulcers, Diabetic Foot Ulcers
Interventions: PICO System, tNPWT System; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 15
States / cities: Carlsbad, California • Fresno, California • Martinez, California + 12 more

Conditions: Lower Limb Injury, Ankle Foot Orthosis (AFO), Lower Limb Trauma
Interventions: Advanced Ankle Foot Orthosis (AFO), Conventional Ankle Foot Orthosis (AFO); Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Tampa, Florida • New York, New York

Conditions: Anterior Cruciate Ligament Injuries
Interventions: blood flow restriction, physical therapy standard of care; Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 34 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Syndesmotic Injuries, Ligament Rupture, Bimalleolar Fractures, Trimalleolar Fractures
Interventions: Tight rope fixation, Tight rope fixation with an anterior inferior tibiofibular ligament (AITFL) repair augmentation with an internal brace; Device
Lead sponsor: Vann Virginia Center for Orthopaedics dba Atlantic Orthopaedic Specialists; Other
Eligibility: 18 Years to 80 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Virginia Beach, Virginia

Conditions: ACL Tear
Interventions: Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab; Device · Other
Lead sponsor: Candice Dunkin, MS, LAT, ATC; Other
Eligibility: 16 Years to 22 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Tibial Fracture, Soft Tissue Injury
Interventions: Hyperbaric Oxygen Treatment; Other
Lead sponsor: Bayside Health; Government
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2016
U.S. locations: 1
States / cities: Concord, California

Conditions: ACL Injury, ACL Reconstruction, Scar Formation
Interventions: Losartan, Placebo; Drug · Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Tibial Meniscus Injuries, Knee Injuries, Knee Injuries and Disorders
Interventions: Lipogems, Normal Saline; Device · Drug
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 45 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence, Opioid Analgesia
Interventions: Buprenorphine Transdermal System, Placebo Patch; Drug
Lead sponsor: Jenna-Leigh Wilson; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Diabetic Foot Ulcer
Interventions: Alert for temperature delta; Device
Lead sponsor: DAPS Health LLC; Other
Eligibility: 35 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Annapolis, Maryland

Conditions: Foot Injuries and Disorders
Interventions: Structure Sensor, Caliper; Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Knee Injury
Interventions: CR Plug; Other
Lead sponsor: RTI Surgical; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 4
States / cities: Birmingham, Alabama • Phoenix, Arizona • Englewood, Colorado + 1 more

Conditions: Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
Interventions: Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis; Device
Lead sponsor: VA Eastern Colorado Health Care System; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: ACL Injury, Post Operative Pain
Interventions: Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tibial Fractures
Interventions: Not listed
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Athens, Georgia • Fort Worth, Texas

Conditions: Hip Fractures, Myocardial Injury
Interventions: Accelerated medical clearance and surgery; Other
Lead sponsor: Population Health Research Institute; Other
Eligibility: 45 Years and older
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 23
States / cities: Chandler, Arizona • Davis, California • Irvine, California + 19 more

Conditions: Hip Fractures
Interventions: progressive resistance exercise, TENS; Other
Lead sponsor: Arcadia University; Other
Eligibility: 65 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Glenside, Pennsylvania

Conditions: Anterior Cruciate Ligament Injuries
Interventions: aNMT Biofeedback, Sham Biofeedback; Other
Lead sponsor: Emory University; Other
Eligibility: 12 Years to 19 Years · Female only
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Flowery Branch, Georgia • Cincinnati, Ohio

Conditions: Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer, Venous Ulcer
Interventions: Debritom; Device
Lead sponsor: Stephanie Wu; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: North Chicago, Illinois

Search by objective public record fields.

Post Market Clinical Evaluation of Gamma 4

Meniscal Root Tears: Evaluation Using an Ultrahigh MRI

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds

Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity

Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)

IM ABLE 2: Injuries Managed With Advanced Bracing for Lower Extremities

Blood Flow Restriction Training in ACL Surgery

Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.

ACL Bone Health and Loading Study

Hyperbaric Oxygen in Lower Leg Trauma

Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction

Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

A Predictive Technology for Prevention of Diabetic Foot Ulcers

SCANREP: Reliability of 3D Lower Limb Scanning

Evaluation of the CR Plug for Repair of Defects Created at the Harvest Site From an Autograft in the Knee.

What is the Optimal Stiffness and Height of a Running-specific Prosthesis?

iPACK for Post-op Pain Following ACL Reconstruction

Safety Study of Treatment of Leg Fractures

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

Effect of Leg Strengthening Exercise After Hip Fracture

Neuroplastic Mechanisms Underlying Augmented Neuromuscular Training

Debritom - Micro Water Jet Technology and Wound Healing