Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:58 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Ankle Sprains
Interventions: MRX-7EAT, Placebo, Lidocaine, Etodolac; Drug
Lead sponsor: MEDRx USA, Inc.; Industry
Eligibility: 14 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 33
States / cities: Phoenix, Arizona • North Little Rock, Arkansas • Chico, California + 30 more

Conditions: Anterior Cruciate Ligament Injury
Interventions: Not listed
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 10 Years to 70 Years
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anterior Cruciate Ligament Injuries
Interventions: post-surgical functional bracing; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 14 Years to 39 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia, Nonunion of Fracture of Femur (Diagnosis), Tibia Fracture
Interventions: Distal targeting jig, Free-hand/perfect circles technique; Device · Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Ankle Sprain
Interventions: Unilateral CAI; Device
Lead sponsor: University of Toledo Health Science Campus; Other
Eligibility: 18 Years to 30 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
Interventions: Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction; Biological · Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Injury of Anterior Cruciate Ligament
Interventions: Not listed
Lead sponsor: The Hawkins Foundation; Other
Eligibility: 10 Years to 50 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Depression, Anterior Cruciate Ligament Injuries, Mental Health Issue
Interventions: Virtual Psychological Intervention: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 13 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Ankle Fracture, Pilon Fracture
Interventions: ankle or distal tibia surgery; Procedure
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 3
States / cities: Jacksonville, Florida • New York, New York

Conditions: Hip Fractures
Interventions: Tranexamic acid, Normal Saline; Drug
Lead sponsor: Community Memorial Health System; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Ventura, California

Conditions: Ankle Injuries
Interventions: bupivacaine hydrochloride and betamethasone sodium phosphate, bupivacaine hydrochloride; Drug
Lead sponsor: Sanford Health; Other
Eligibility: 16 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain, Phantom Pain Following Amputation of Lower Limb, Phantom Pain Following Amputation of Upper Limb, Amputation, Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist, Upper Limb Amputation Below Elbow (Injury), Upper Limb Amputation Above Elbow (Injury), Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation at Ankle (Injury)
Interventions: Coapt Phantom Limb Pain Management System; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Rupture of Anterior Cruciate Ligament
Interventions: cryotherapy, TENS; Other
Lead sponsor: University of Virginia; Other
Eligibility: 15 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Ankle Injuries, Ankle Inversion Sprain
Interventions: External focus of attention visual feedback, External focus of attention auditory feedback, Internal focus of attention video feedback, No feedback; Other
Lead sponsor: University of North Carolina, Charlotte; Other
Eligibility: 18 Years to 40 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Femoral Fractures
Interventions: Abaloparatide, Placebo; Drug
Lead sponsor: Daniel Horwitz; Other
Eligibility: 65 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Danville, Pennsylvania

Conditions: Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions: Blood Flow Restriction (BFR) Therapy, Physical Therapy; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Anterior Cruciate Ligament Tear
Interventions: Delfi, Standard rehabilitation; Device · Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 30 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 27 Years to 89 Years · Male only
Enrollment: 4,549 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Femoral Neck Fractures
Interventions: Hip arthroplasty, Internal fixation; Procedure
Lead sponsor: University of Southern California; Other
Eligibility: 60 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 22
States / cities: Irvine, California • Los Angeles, California • San Francisco, California + 16 more

Conditions: Hip Fractures
Interventions: Energy absorbing and distributing trochanteric pad; Device
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 66 Years and older
Enrollment: 546 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2006
U.S. locations: 4
States / cities: Baltimore, Maryland • Boston, Massachusetts • St Louis, Missouri

Conditions: Knee Dislocations, Multiple Ligament Knee Injuries
Interventions: Early Surgery, Delayed Surgery, Early Rehab, Delayed Rehab; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 16 Years to 55 Years
Enrollment: 690 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: ACL, Anterior Cruciate Ligament Injuries
Interventions: Genicular Nerve Block with bupivacaine and preservative free dexamethasone; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Distal Femur Fractures
Interventions: DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw); Device
Lead sponsor: AO Innovation Translation Center; Other
Eligibility: 21 Years to 120 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 5
States / cities: Sacramento, California • Columbia, Missouri • St Louis, Missouri + 2 more

Conditions: INCOMPLETE SPINAL CORD INJURY (ASIA D), Able Bodied
Interventions: Acute Intermittent Hypoxia (AIH); Other
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Boulder, Colorado

Search by objective public record fields.

MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains

Clinical Outcome Following Arthroscopic Knee Surgery

Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial

Distal Targeter vs Free-hand

The Effect of Five-Toed Socks on Postural Control Among Active Individuals Who Have Chronic Ankle Instabilities

Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction

Sport Cord Test Following ACL Reconstruction

Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention

Trauma Expectation Factor Trauma Outcome Measure

Blood Loss After Early TXA in Hip Fractures.

Investigation of Corticosteroid Versus Placebo Injection in Patients With Syndesmotic Ligament Injury or High Ankle Sprain

VR to Evaluate Phantom Limb Pain

Quadriceps Function Prior to Anterior Cruciate Ligament Reconstruction

External Versus Internal Feedback in Patients With Chronic Ankle Instability

Supracondylar Distal Femur Fractures and Abaloparatide

BFR After Biceps Tendon Repair and MPFLR

Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction

Longitudinal Study of Weight Change Following Lower Limb Amputation

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

The HIP Impact Protection Program (HIP PRO)

STaR Trial: Multiple Ligament Knee Injuries

Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery

Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation

Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function