Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:09 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Femur Fracture
Interventions: Femoral Traction; Procedure
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Injuries, Knee Imlant
Interventions: MicroPort Medial Pivot TKA, DePuy Attune PCR TKA; Device
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 3
States / cities: Las Vegas, Nevada • Knoxville, Tennessee

Conditions: Hip Fractures, Femoral Fractures, Fractures, Bone
Interventions: Application of knowledge; Other
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Wound
Interventions: Fibrillar collagen powder dressing; Device
Lead sponsor: Medline Industries; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Fresno, California

Conditions: Tibial Fractures
Interventions: reamed, interlocking intramedullary nail, locking periarticular plate; Device
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2020
U.S. locations: 27
States / cities: Birmingham, Alabama • Davis, California • San Francisco, California + 22 more

Conditions: Tibial Shaft Fracture, Tibial Plateau Fracture
Interventions: Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome; Procedure
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Surgical Wound Infection
Interventions: Chlorhexidine gluconate (4%), Mupirocin 2% Ointment; Drug
Lead sponsor: Cooper Norcross Health; Other
Eligibility: 18 Years and older
Enrollment: 848 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 1
States / cities: Marlton, New Jersey

Conditions: Femoral Fractures
Interventions: 95-degree Angled Blade Plate, 4.5mm Condylar Locking Plate; Device
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 16 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Femoral Fracture, Tibial Fractures
Interventions: Standard of Care Physical Therapy Program, Speed Walking Intervention; Other
Lead sponsor: Brian W. Noehren; Other
Eligibility: 18 Years to 50 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Lexington, Kentucky • Nashville, Tennessee

Conditions: Hemorrhage, Pelvic Fracture
Interventions: Pelvic Binder; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 64 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Tibia Fracture, Femur Fracture, Humerus Fracture
Interventions: Narcotics alone, Narcotics and NSAIDS; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lower Extremity Weakness Distal, Distorted; Balance
Interventions: Assessment and education, Healthy Steps with Falls Case Management, Healthy Steps in Motion; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years to 100 Years
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Fracture of Distal Femur
Interventions: Not listed
Lead sponsor: Legacy Biomechanics Laboratory; Other
Eligibility: 17 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions: Carbon Fiber Custom Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Leg Ulcer
Interventions: CO2RE® (Syneron Candela Corp, Wayland, MA), Sham laser treatment; Device · Other
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: St Louis, Missouri

Conditions: Tibial Fracture
Interventions: CERAMENT|G, SOC treatment; Device · Procedure
Lead sponsor: BONESUPPORT AB; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 17
States / cities: Birmingham, Alabama • Irvine, California • Los Angeles, California + 12 more

Conditions: Knee Injuries, Knee Injuries and Disorders, Opioid Use
Interventions: Opioid Reduction Program; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain, Achilles Tendon Rupture, Flexor Hallucis Longus on the Left, Flexor Digitorum Longus on the Left, Ankle Sprains, Flexor Hallucis Longus on the Right, Flexor Digitorum Longus on the Right
Interventions: Grappler® Interference Screw System; Device
Lead sponsor: Paragon 28; Industry
Eligibility: Not listed
Enrollment: 50 participants
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Worthington, Ohio

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Operant Conditioning, Control; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 45 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Lower Extremity Injury
Interventions: Platelet Poor Plasma (PPP) Injection; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 3
States / cities: Englewood, Colorado • Atlanta, Georgia • Iowa City, Iowa

Conditions: Skin Carcinoma
Interventions: Best Practice, Educational Intervention, Electronic Health Record Review, Follow-Up Care, Medical Device Usage and Evaluation, Negative Pressure Wound Therapy, Photography, Questionnaire Administration; Other · Procedure
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 19 Years to 79 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Meniscus Tear, Tibial
Interventions: Non-Operative Pain Management, Operative treatment arm will undergo transtibial medial meniscus root repair within 3 weeks of enrollment; Other · Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2030
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Severe Distal Tibia Injury, Severe Ankle Injury, Severe Foot Injury, Major Soft Tissue Loss, Major Bone Articular Surface Loss, Major Ankle Articular Surface Loss
Interventions: Not listed
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 60 Years
Enrollment: 664 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 33
States / cities: Birmingham, Alabama • San Diego, California • San Francisco, California + 26 more

Conditions: Hip Fractures, Surgical Blood Loss
Interventions: Tranexamic Acid, Placebo; Drug · Other
Lead sponsor: Good Samaritan Regional Medical Center, Oregon; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Corvallis, Oregon

Search by objective public record fields.

Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures

In Vivo Kinematics for Subjects Having a MicroPort Medial Pivot or DePuy Attune PCR TKA

Performance Improvement Program on Imaging II

An Evaluation of a Fibrillar Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds

A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures

Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

Plate Fixation of Distal Femur Fractures: A Protocol for a Study of Two Plate Options

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

Pre-hospital Advanced Therapies for Control of Hemorrhage - Pelvis

Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture

Assessment and Referral Versus Exercise in Primary Prevention of Falls: PA Healthy Steps Program

Plating of Distal Femur Fractures by Far Cortical Locking Using MotionLoc Screws

Custom Dynamic Orthoses to Reduce Articular Contact Stress

Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wound Healing

Study Evaluating CERAMENT™|G in Open Diaphyseal Tibial Fractures

Opioid Reduction Program for Total Knee Replacement Patients

Grappler® Interference Screw Post-Market Clinical Follow-Up Study

Operant Conditioning After ACL Reconstruction

Cohort Study of PPP Injections for Athletes With Muscle Injury

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol

Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures