Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:25 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 803 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Extremity Injuries Lower Clear all

Conditions: Ankle Sprains
Interventions: High Velocity Low Amplitude mobilization, Exercise protocol; Other
Lead sponsor: Shenandoah University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Fayetteville, North Carolina • Winchester, Virginia

Conditions: Ankle Injuries, Foot Injury
Interventions: Monster Screw System; Device
Lead sponsor: Paragon 28; Industry
Eligibility: Not listed
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Jackson, Michigan

Conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
Interventions: Anterior cruciate ligament reconstruction (ACLR), Lateral extra-articular tenodesis (LET); Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 14 Years to 25 Years
Enrollment: 1,272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 14
States / cities: Redwood City, California • San Francisco, California • Orlando, Florida + 11 more

Conditions: Hip Fractures
Interventions: Tranexamic Acid Injectable Solution, Placebo; Drug · Other
Lead sponsor: Lancaster General Hospital; Other
Eligibility: 65 Years and older
Enrollment: 283 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Hip Fractures, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
Interventions: My Anesthesia Choice-HF Model; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 50 Years and older
Enrollment: 1,881 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 6
States / cities: Gainesville, Florida • Detroit, Michigan • Lebanon, New Hampshire + 3 more

Conditions: Knee Dislocation
Interventions: Compass Universal Hinge External Fixator, Non-invasive External Knee Brace; Device · Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2008
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Valgus Deformity, Not Elsewhere Classified, Knee, Injury, Knee
Interventions: Single-Leg Drop Vertical Jump, Combined Focus of Attention Instruction, External Focus of Attention Instruction, No instruction; Other
Lead sponsor: Bahçeşehir University; Other
Eligibility: 18 Years to 30 Years · Female only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Lower Extremity Musculoskeletal Injury
Interventions: Shear wave elastography and microvascular flow imaging.; Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Eugene, Oregon • Portland, Oregon

Conditions: Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
Interventions: App for in-bed conditioning exercises, Usual care; Device · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury, Hip Injuries, Liver Injury, Spleen Injury, Renal Injury, Diaphragm Injury, Aortic Rupture, Aortic Dissection, Bowel Disease, Vascular System Injuries, Sacral Fracture
Interventions: There are no interventions associated with this study; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: Not listed
Enrollment: 12,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis, Femoral Neck Fractures, Trochanteric Fractures, Surgery
Interventions: Insignia uncemented Hip Stem; Device
Lead sponsor: Stryker Orthopaedics; Industry
Eligibility: 18 Years and older
Enrollment: 313 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2034
U.S. locations: 11
States / cities: Phoenix, Arizona • San Francisco, California • Chicago, Illinois + 8 more

Conditions: Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
Interventions: Metformin, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 45 Years
Enrollment: 512 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 9
States / cities: Atlanta, Georgia • Iowa City, Iowa • Lexington, Kentucky + 6 more

Conditions: Ankle Fracture
Interventions: Exparel; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
Interventions: Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation; Device · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 35 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Chapel Hill, North Carolina

Conditions: Ankle Fracture
Interventions: Fracture union; Other
Lead sponsor: University of Florida; Other
Eligibility: 55 Years to 85 Years
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Ankle Injuries
Interventions: Topical IBU twice daily, Placebo twice daily, Topical IBU three times daily, Placebo three times daily; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 12 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 19
States / cities: Sheffield, Alabama • Tucson, Arizona • Anaheim, California + 11 more

Conditions: Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
Interventions: Auricular acupuncture; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: ACL Injury
Interventions: Blood Flow Restriction (BFR) therapy, Standard REHAB; Other
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 15 Years to 45 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis, Dislocation, Hip, Femoral Neck Fractures, Trochanteric Fractures, Revision Surgeries
Interventions: G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2037
U.S. locations: 6
States / cities: Little Rock, Arkansas • Jersey City, New Jersey • New York, New York + 3 more

Conditions: Ankle Fractures
Interventions: Long-Acting Local Anesthesia, Regional Anesthesia; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Somatic Dysfunction of Sacral Region, Somatic Dysfunction of Both Sacroiliac Joints, Somatic Dysfunction of Bilateral Lower Extremities
Interventions: Osteopathic Assessment; Other
Lead sponsor: The Touro College and University System; Other
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Ankle Injuries, Syndesmotic Injuries, Ankle Fractures
Interventions: Arthrex Tightrope, Synthes Fibulink; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Distal Femur Fractures
Interventions: Placement of RSA beads; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Foot Surgery, Ankle Surgery
Interventions: Not listed
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: Not listed
Enrollment: 1,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Effect of Mobilization in Conjunction With Exercise in Participants With a History of Chronic Ankle Instability

Monster Screw System Post-Market Clinical Follow-Up Study

STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon

Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population

Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)

Compass Hinge Stabilization of Knee Dislocations: A Randomized Trial

External vs Combined Focus Effects on Landing in Female Athletes

Evaluation of Lower Extremity Athletic Injuries and Response to Treatment Using SWE and MFI

Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

Insignia™ Hip Stem Outcomes Study

Preventing Injured Knees From osteoArthritis: Severity Outcomes

Exparel and Ankle Surgery

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

Ankle Fracture Treatment in the Elderly

5% Topical Ibuprofen (IBU) for Ankle Sprain

Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture

BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft

G7 Dual Mobility With Vivacit-E or Longevity PMCF

Randomized Controlled Trial for Ankle Fracture Pain Control

An Osteopathic Assessment of Lower Extremity Somatic Dysfunction in Runners

Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures

Pre-post Spinal Popliteal Block