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ClinicalTrials.gov public records Last synced Sep 22, 2026, 10:06 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Eyeglasses Clear all
Completed Not applicable Interventional Results available

Trial of Overminus Spectacle Therapy for Intermittent Exotropia

NCT02807350
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Overminus treatment, Non-overminus treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 10 Years
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
59
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional

The Effect Of Virtual Reality Glasses On The Behavior Of Children With Autism Spectrum Disorder

NCT03853265
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Simulated dental office visit
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
5 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Peripheral Prism Glasses for Hemianopia

NCT00494676
View directory record Official record
Conditions
Homonymous Hemianopia
Interventions
High power (57 prism diopter) peripheral prism glasses, Low power sham peripheral prism glasses
Device
Lead sponsor
Alexandra Bowers
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
12
States / cities
Birmingham, Alabama • Palo Alto, California • Jupiter, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses

NCT00585026
View directory record Official record
Conditions
Refractive Error, Presbyopia, Asthenopia, Eyeglasses
Interventions
D-28 bifocal lenses and frame, Progressive addition computer lenses and frame
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 14, 2011 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional

Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria

NCT00785135
View directory record Official record
Conditions
Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
Interventions
Lenses containing prismatic correction, Lenses not containing prismatic correction
Device
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
14 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Birmingham, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Glasses for Adolescent Delayed Sleep-Wake Phase Disorder

NCT04378933
View directory record Official record
Conditions
Delayed Sleep-Wake Phase Disorder
Interventions
Amber Glasses, Clear Lens Glasses
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
14 Years to 17 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Blue Wavelength Light-blocking Glasses in ADHD-Insomnia

NCT01557595
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Delayed Sleep Phase Type Circadian Rhythm Sleep Disorder
Interventions
Polarized glasses designed to filter out blue light
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 22, 2026, 10:06 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Comparison Between Spectacles and Contact Lenses

NCT06905912
View directory record Official record
Conditions
Photophobia
Interventions
Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

NCT04827147
View directory record Official record
Conditions
Homonymous Hemianopia
Interventions
Multi-Periscopic Prism (MPP) glasses, Fresnel Peripheral Prism (FPP) glasses
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
7 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Denver, Colorado • Palm Springs, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia

NCT02687581
View directory record Official record
Conditions
Amblyopia
Interventions
IO-therapy Glasses, patch
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 8 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Phase 3 Interventional

An Evaluation of Treatment of Amblyopia in Children 7 To <18 Years Old

NCT00094692
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, spectacles, atropine
Device · Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
7 Years to 17 Years
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
View directory record Official record
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 22, 2026, 10:06 PM EDT
Recruiting Phase 2 Interventional

Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome

NCT07490444
View directory record Official record
Conditions
Refractive Error Correction, Visual Acuity
Interventions
Metric-optimized spectacles, Routine Clinical Spectacles
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional

Visual Performance of Highly Aspherical Lenslet Spectacles in Children (Ancillary to WS10246)

NCT07668102
View directory record Official record
Conditions
Myopia
Interventions
HAL spectacle lens, Single Vision spectacle lens
Device
Lead sponsor
Essilor International
Industry
Eligibility
6 Years to 12 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
7
States / cities
San Diego, California • Longwood, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Accuracy of an Automated Refractor to Provide Well-tolerated Eyeglass Prescriptions

NCT06883032
View directory record Official record
Conditions
Refractive Errors
Interventions
AR Eyeglasses first, SR Eyeglasses second, SR Eyeglasses first, AR Eyeglasses second
Other
Lead sponsor
PlenOptika, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Results available

Feasibility of EnChroma Use in the Emergency Department Setting

NCT04021914
View directory record Official record
Conditions
Color Vision Defects
Interventions
EnChroma glasses
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Gunnar Computer Glasses on Viewing Comfort and Performance

NCT02925884
View directory record Official record
Conditions
Dry Eye, Eye Strain, Visual Acuity, Color Perception
Interventions
Gunnar OTC Glasses
Device
Lead sponsor
Pacific University
Other
Eligibility
18 Years to 42 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Forest Grove, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Results available

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Child and Adolescent Patients With Migraine

NCT01942486
View directory record Official record
Conditions
Migraine Disorders, Photophobia
Interventions
Investigational Coating
Device
Lead sponsor
University of Utah
Other
Eligibility
7 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients

NCT03811249
View directory record Official record
Conditions
Presbyopia
Interventions
VisAbility™ Micro Insert
Device
Lead sponsor
Refocus Group, Inc.
Industry
Eligibility
45 Years to 60 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
13
States / cities
Orange, California • San Diego, California • Honolulu, Hawaii + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 22, 2026, 10:06 PM EDT
Completed Phase 1 Interventional

Rehabilitation Glasses for the Treatment of Hemispatial Neglect

NCT02695927
View directory record Official record
Conditions
Hemispatial Neglect
Interventions
Computer rehabilitation glasses
Device
Lead sponsor
Chun Lim
Other
Eligibility
21 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Sep 22, 2026, 10:06 PM EDT
Terminated Not applicable Interventional Results available

Comparison of AmblyzTM Glasses and Patching for Amblyopia

NCT01973348
View directory record Official record
Conditions
Amblyopia
Interventions
4-hour AmblyZ glasses, 12-hour AmblyZ glasses, 2-hour patching, 6-hour patching
Device
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 8 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Sep 22, 2026, 10:06 PM EDT
Recruiting Phase 3 Interventional

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

NCT04378790
View directory record Official record
Conditions
Amblyopia
Interventions
Patching, Glasses
Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
68
States / cities
Birmingham, Alabama • Glendale, Arizona • Phoenix, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 22, 2026, 10:06 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spectacle Lens Visual Acuity Assessments Study

NCT05650190
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
9 Years to 14 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 22, 2026, 10:06 PM EDT