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ClinicalTrials.gov public records Last synced Oct 17, 2026, 2:43 PM EDT

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Showing 793–816 of 1,933 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Familial Alzheimer Disease Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Patient-Centered Dementia Care Practice Coaching Intervention

NCT06249204
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Coaching Group
Behavioral
Lead sponsor
Alzheimer's Disease and Related Disorders Association, Inc
Other
Eligibility
18 Years to 100 Years
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 2 Interventional Results available

Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis

NCT01083316
View directory record Official record
Conditions
Amyloidosis
Interventions
Bortezomib, Dexamethasone, Melphalan
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2020 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers

NCT05916664
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia, Frontotemporal Dementia, Mixed Dementia
Interventions
Kinto Care Coaching
Behavioral
Lead sponsor
Kinto
Industry
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 2 Interventional

Nefiracetam in the Treatment of Alzheimer's Disease

NCT00001933
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Nefiracetam
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Not applicable Interventional

Optimizing a Smartphone Application for Individuals With Eating Disorders

NCT02503098
View directory record Official record
Conditions
Eating Disorders, Binge Eating Disorder, Bulimia Nervosa
Interventions
Recovery Record adaptive smartphone application, Recovery Record standard smartphone application
Behavioral
Lead sponsor
Recovery Record Research
Industry
Eligibility
16 Years and older
Enrollment
3,340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
San Francisco, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 17, 2026, 2:43 PM EDT
Active, not recruiting Not applicable Interventional

Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

NCT06940687
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Mild Cognitive Impairment, Peer-bonded Caregiver, Caregiver
Interventions
Pre-recorded Music Session, Live Music Session
Behavioral
Lead sponsor
Yale University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 1 Interventional

Alzheimer's Disease Stem Cells Multiple Infusions

NCT04040348
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Approximately 100 million cells allogeneic hMSC
Biological
Lead sponsor
Bernard (Barry) Baumel
Other
Eligibility
50 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

NCT05374278
View directory record Official record
Conditions
Alzheimer Disease, Frontotemporal Dementia, Dementia
Interventions
[18F]RP-115 PET/MRI or PET/CT and MRI
Drug
Lead sponsor
David Wilson
Other
Eligibility
40 Years to 75 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Not applicable Interventional

Promoting Independence With Compensatory Cognitive Rehabilitation

NCT04820335
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease
Interventions
Structured External Memory Aid Treatment (SEMAT)
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
60 Years to 90 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Not listed Phase 2 Interventional

Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha

NCT00031018
View directory record Official record
Conditions
Memory Disorders, Alzheimer's Disease
Interventions
Aricept, IFN-alpha2A
Drug
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2008 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 3 Interventional Results available

Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type

NCT01922258
View directory record Official record
Conditions
Agitation Associated With, Alzheimer's Disease, Alzheimer's Type, Mental Disorder, Nervous System Diseases
Interventions
Brexpiprazole, OPC-34712
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
55 Years to 90 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
28
States / cities
Imperial, California • Lakewood, California • Long Beach, California + 21 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Alzheimer's Disease Prevention Trial

NCT00000176
View directory record Official record
Conditions
Alzheimer Disease, Memory Disorders
Interventions
Estrogen, Estrogen and Progesterone
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2007
U.S. locations
22
States / cities
Birmingham, Alabama • Irvine, California • Stamford, Connecticut + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2010 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BCT Intervention For Walking Habit Among Caregivers of People With AD/ADRD

NCT06803797
View directory record Official record
Conditions
Inactivity, Physical
Interventions
Behavior Change Technique Package
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

First in Human Study for Safety and Tolerability of AL003.

NCT03822208
View directory record Official record
Conditions
Healthy, Alzheimer Disease
Interventions
AL003, Saline Solution
Biological · Other
Lead sponsor
Alector Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
5
States / cities
Delray Beach, Florida • Lady Lake, Florida • Orlando, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Oct 17, 2026, 2:43 PM EDT
Recruiting Not applicable Interventional

The BRAIN App (Phase 2 SBIR)

NCT06298474
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Vascular Dementia
Interventions
The BRAIN App
Behavioral
Lead sponsor
Hopeful Aging
Industry
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Winchester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 3 Interventional Results available

Rosiglitazone (Extended Release Tablets) As Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease

NCT00428090
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Rosiglitazone
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
50 Years to 90 Years
Enrollment
862 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
41
States / cities
Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 34 more
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 17, 2026, 2:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test

NCT05107882
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia
Interventions
Not listed
Lead sponsor
Optina Diagnostics Inc.
Industry
Eligibility
50 Years to 90 Years
Enrollment
466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
4
States / cities
Miami, Florida • Las Vegas, Nevada • Norfolk, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 17, 2026, 2:43 PM EDT
Active, not recruiting Early Phase 1 Interventional

Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease

NCT03560960
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
Pramlintide challenge test
Drug
Lead sponsor
Boston University
Other
Eligibility
60 Years to 90 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias

NCT04786223
View directory record Official record
Conditions
Lewy Body Dementia (LBD), Alzheimer Dementia (AD)
Interventions
C-11 ER-176, Blood Test
Drug · Diagnostic Test
Lead sponsor
Val Lowe
Other
Eligibility
60 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 2 Interventional Results available

Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease

NCT00722046
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
PF-04360365 0.1 mg/kg, PF-04360365 0.5 mg/kg, PF-04360365 1 mg/kg, Placebo, PF-04360365 3 mg/kg, PF-04360365 8.5 mg/kg
Biological · Drug
Lead sponsor
Pfizer
Industry
Eligibility
50 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
15
States / cities
Peoria, Arizona • Phoenix, Arizona • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 17, 2026, 2:43 PM EDT
Terminated Phase 2 Interventional Results available

Study of ASN51 in Adults With Early Alzheimer's Disease

NCT06677203
View directory record Official record
Conditions
Alzheimer Disease
Interventions
ASN51, Placebo
Drug
Lead sponsor
Asceneuron S.A.
Industry
Eligibility
50 Years to 80 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
7
States / cities
Clermont, Florida • Lady Lake, Florida • Maitland, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2025 · Synced Oct 17, 2026, 2:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Care Planning for a Loved One With Dementia: Knowledge, Preparing for Decisions, and Emotions

NCT05165186
View directory record Official record
Conditions
Dementia, Dementia Frontotemporal, Dementia Alzheimers, Dementia, Mild, Dementia Moderate, Dementia Severe, Caregiver Burnout, Caregiver Stress Syndrome
Interventions
Video Intervention Arm
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2023 · Synced Oct 17, 2026, 2:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

NCT04510168
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
11C-ER176, [F-18]MK-6240, Florbetaben, Magnetic Resonance Imaging
Drug · Other
Lead sponsor
Jose Gutierrez, MD, MPH
Other
Eligibility
50 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 17, 2026, 2:43 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease

NCT02547818
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
ALZT-OP1a, ALZT-OP1b, Placebo ALZT-OP1a, Placebo ALZT-OP1b
Drug · Other
Lead sponsor
AZTherapies, Inc.
Industry
Eligibility
55 Years to 79 Years
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
69
States / cities
Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 17, 2026, 2:43 PM EDT