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ClinicalTrials.gov public records Last synced Oct 18, 2026, 4:12 AM EDT

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Showing 1–24 of 126 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Fat Reduction Clear all
Completed Not applicable Interventional

Study of the Carbon Dioxide Treatment for Fat Reduction

NCT00974415
View directory record Official record
Conditions
Overweight
Interventions
CO2, Sham
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional

Clinical Investigation of Non Invasive Fat Reduction

NCT01842802
View directory record Official record
Conditions
Subcutaneous Fat
Interventions
Diode Laser, YAG laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
20 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Single Blind, Randomized, Placebo-controlled, Phase 2a, 2-cohort Study for the Evaluation of Safety and Efficacy of RZL-012 for Submental Fat Reduction in Healthy Volunteers.

NCT04086823
View directory record Official record
Conditions
Submental Fat
Interventions
RZL-012, Placebo
Drug
Lead sponsor
Raziel Therapeutics Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance

NCT00264251
View directory record Official record
Conditions
HIV Infections, Insulin Resistance, Obesity
Interventions
Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
Behavioral · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
20 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2007 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional

Healthy Eating Through Reduction Of Excess Sugar

NCT02948647
View directory record Official record
Conditions
NAFLD
Interventions
Standard of care plus sugar-reduction education
Other
Lead sponsor
University of Southern California
Other
Eligibility
12 Years to 18 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Craving and Lifestyle Management Through Mindfulness Study

NCT01250509
View directory record Official record
Conditions
Obesity
Interventions
Craving and Lifestyle Management through Mindfulness
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fat Reduction in the Submandibular/Submental Area

NCT02700165
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

UltraShape Power for Abdominal Fat and Circumference Reduction

NCT02748928
View directory record Official record
Conditions
Excess Abdominal Fat
Interventions
UltraShape Power
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 60 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
8
States / cities
Sacramento, California • Jacksonville Beach, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction

NCT04012814
View directory record Official record
Conditions
Adipose Tissue Atrophy
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Altos, California • Sacramento, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-level Laser and Lifestyle Modifications

NCT05083442
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Low Level Laser Therapy, Sham (placebo)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 18, 2026, 4:12 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Effects of a Red/Gold/IR LED Combination Light on Reduction of Fat

NCT04525573
View directory record Official record
Conditions
Body Image, Diabetes Mellitus, Type 2
Interventions
LLLT Combination Red/Gold/IR Therapy
Device
Lead sponsor
Ward Photonics LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Schaumburg, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outer Thigh Study With Varied Treatment Parameters

NCT02081209
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Marina del Rey, California • Pleasanton, California
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 18, 2026, 4:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Feasibility of Producing the Appearance of a Gluteal Lift Post Cryolipolysis

NCT04553627
View directory record Official record
Conditions
Subcutaneous Fat
Interventions
ZELTIQ thermoelectric device
Device
Lead sponsor
Riverchase Dermatology
Other
Eligibility
22 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen

NCT05540080
View directory record Official record
Conditions
Fat Burn
Interventions
BTL-899
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Sacramento, California • Greenwood Village, Colorado • Marietta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)

NCT04897412
View directory record Official record
Conditions
Subcutaneous Fat
Interventions
CBL-514 Injection, Placebo
Drug · Other
Lead sponsor
Caliway Biopharmaceuticals Co., Ltd.
Industry
Eligibility
18 Years to 64 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
4
States / cities
Chicago, Illinois • Omaha, Nebraska • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Trusculpt (Radio Frequency) Device For Thigh Circumference Reduction

NCT01665118
View directory record Official record
Conditions
Body Fat
Interventions
Trusculpt (Radio Frequency) Device
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
Brisbane, California • Montclair, New Jersey • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VelaShape III Device in Comparison to Cryolipolysis for Circumferential Reduction

NCT02143960
View directory record Official record
Conditions
Abdominal Fat
Interventions
VelaShape III, CoolSculpt
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Metairie, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area

NCT01426373
View directory record Official record
Conditions
Moderate or Severe Submental Fullness
Interventions
Deoxycholic acid injection
Drug
Lead sponsor
Kythera Biopharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
18
States / cities
Beverly Hills, California • La Jolla, California • San Juan Capistrano, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Factors Affecting Caloric Regulation in Human Feeding

NCT00108784
View directory record Official record
Conditions
Obesity
Interventions
Reduced-energy-density diet
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
20 Years to 60 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tissue Optimization on Cryolipolysis Procedures for Fat Layer Reduction

NCT01728857
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study to Assess Non-Invasive Subcutaneous Fat Reduction in the Submental, Inner Thigh and Back/Bra Areas With the CoolSculpting Elite System

NCT07122583
View directory record Official record
Conditions
Non-Surgical Fat Reduction
Interventions
CoolSculpting Elite System
Device
Lead sponsor
AbbVie
Industry
Eligibility
22 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Vista, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Body Fat Reducing Effect and Safety of Enzymatically Modified Isoquercitrin in Overweight and Obese Subjects

NCT02818699
View directory record Official record
Conditions
Overweight, Obese
Interventions
Placebo, EMIQ
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

An Evaluation of the Safety and Efficacy of LIPO-102 for the Reduction of Subcutaneous Abdominal Adiposity

NCT01096979
View directory record Official record
Conditions
Subcutaneous Abdominal Adiposity
Interventions
LIPO-102, Placebo
Drug
Lead sponsor
Neothetics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Anaheim, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 18, 2026, 4:12 AM EDT
Completed Phase 3 Interventional Results available

Patient Experience Study of Deoxycholic Acid Injection

NCT02007434
View directory record Official record
Conditions
Moderate or Severe Submental Fullness
Interventions
Deoxycholic Acid Injection, Placebo, Cold Compress, Lidocaine / Epinephrine, Loratadine, Ibuprofen, Compression Chin Strap
Drug · Other
Lead sponsor
Kythera Biopharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Oct 18, 2026, 4:12 AM EDT