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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:16 AM EDT

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Showing 289–312 of 1,046 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Fatigue Symptom Clear all
Recruiting Early Phase 1 Interventional

Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

NCT06472622
View directory record Official record
Conditions
Fatigue Syndrome, Chronic
Interventions
Thermal Pain Stimulation, Physical Effort Stimulation
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

NCT07225088
View directory record Official record
Conditions
Solid Tumor, Solid Tumor, Adult
Interventions
DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 100 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Time-Restricted Eating to Address Persistent Cancer-Related Fatigue

NCT05256888
View directory record Official record
Conditions
Neoplasms, Therapy, Fatigue, Diet Therapy, Time, Survivorship, Fasting, Intermittent
Interventions
Time-restricted eating, Healthy lifestyle education
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Not listed Not applicable Interventional

Evaluate Impact of Exercise Program on Fatigue in Breast Cancer During Chemotherapy

NCT05704842
View directory record Official record
Conditions
Breast Cancer
Interventions
Exercise
Behavioral
Lead sponsor
Virtua Health, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Guided Imagery for a Nonprofit's Employees

NCT02191345
View directory record Official record
Conditions
Focus of Study, Stress
Interventions
Guided Imagery
Behavioral
Lead sponsor
FrontLine Service
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 22, 2026, 1:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dorsolateral Prefrontal Cortex Transcranial Direct Current and Muscle Fatigue Stimulation on Muscle Fatigue

NCT06389162
View directory record Official record
Conditions
Fatigue
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place

NCT03853148
View directory record Official record
Conditions
Pain, Chronic, Fatigue Syndrome, Chronic, Aging
Interventions
Otago, Gentle yogic breathing, Behavioral Activation, Caregiver Gentle yogic breathing
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2022 · Synced Oct 22, 2026, 1:16 AM EDT
Terminated Phase 2 Interventional

Infliximab in Treating Cancer-Related Fatigue in Postmenopausal Women Who Have Undergone Treatment for Breast Cancer

NCT00112749
View directory record Official record
Conditions
Breast Cancer, Fatigue
Interventions
infliximab, Clinical Assessment, Self-report questionnaires, Immune Assessment
Biological · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 22, 2026, 1:16 AM EDT
Enrolling by invitation Not applicable Interventional

Pain & Reward Neuromodulation of CNS Circuits

NCT07525063
View directory record Official record
Conditions
Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed No phase listed Observational

Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer

NCT00950144
View directory record Official record
Conditions
Colorectal Cancer, Depression, Fatigue, Liver Cancer, Pain, Pancreatic Cancer
Interventions
medical chart review, questionnaire administration, study of socioeconomic and demographic variables, quality-of-life assessment
Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Phase 2Phase 3 Interventional

Use of Armodafinil for Fatigue in Sarcoidosis

NCT00555347
View directory record Official record
Conditions
Sarcoidosis, Fatigue, Sleepiness
Interventions
Armodafinil, Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 22, 2026, 1:16 AM EDT
Active, not recruiting Phase 3 Interventional

Relaxation for Women With Breast Cancer Undergoing Radiotherapy

NCT01202851
View directory record Official record
Conditions
Breast Cancer
Interventions
Relaxation Program, Questionnaires, Saliva Testing
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
681 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional

Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled Trial

NCT04620486
View directory record Official record
Conditions
Infections, Bacterial, Sepsis, Alert Fatigue, Health Personnel
Interventions
Epic Best Practice Alert
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effects of Palmar Cooling on Repeated Sprinting Ability

NCT06356142
View directory record Official record
Conditions
Exercise Induced Fatigue
Interventions
Palmar Cooling, Placebo Palmar Cooling
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 30 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 22, 2026, 1:16 AM EDT
Active, not recruiting Phase 2 Interventional

Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer

NCT06295588
View directory record Official record
Conditions
Fatigue, Inflammation
Interventions
Fucoidan extracted from F. Vesiculosus, Fucoidan extracted from U. Pinnatifida
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Withdrawn Phase 2 Interventional

Testosterone for Fatigue in Men With MS

NCT03000127
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
AndroGel 1 % Topical Gel, Placebos
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Los Angeles, California • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Oct 22, 2026, 1:16 AM EDT
Suspended Phase 1 Interventional Accepts healthy volunteers

Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.

NCT03807973
View directory record Official record
Conditions
Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
Interventions
[Zr-89]Oxine-labeled leukocytes PET/MRI
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Light Therapy as Treatment for Fatigue in Multiple Sclerosis

NCT03060759
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Light Therapy box
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Phase 4 Interventional Results available

Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue

NCT03621761
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Telephone-based Cognitive Behavioral Therapy, Modafinil
Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Mindfulness-Based Stress Reduction for Gulf War Syndrome

NCT01267045
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Mindfulness-based stress reduction
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 7, 2015 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Phase 2 Interventional Results available

Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

NCT03844412
View directory record Official record
Conditions
Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome, Migraines, Tension Headache, Endometriosis, Interstitial Cystitis, Back Pain, Chronic Fatigue Syndrome
Interventions
5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline, Placebo cream, Placebo pill
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II

NCT02922439
View directory record Official record
Conditions
Fatigue, Depression, Pain, Sleep Wake Disorders, Chronic Disease
Interventions
Tailored Intervention, Control Intervention
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
40 Years and older
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 22, 2026, 1:16 AM EDT
Recruiting Not applicable Interventional

Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

NCT07151677
View directory record Official record
Conditions
Aphasia Following Cerebral Infarction, Stroke Ischemic, Fatigue Symptom
Interventions
tDCS (active), Attention-focused sentence comprehension treatment, Sentence comprehension treatment, tDCS (sham)
Device · Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Ann Arbor, Michigan • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 1:16 AM EDT
Completed Phase 1Phase 2 Interventional

Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV)

NCT00478465
View directory record Official record
Conditions
Chronic Fatigue Syndrome
Interventions
valganciclovir
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 22, 2026, 1:16 AM EDT