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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:33 AM EDT

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Showing 73–96 of 1,046 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Fatigue Symptom Clear all
Not yet recruiting Phase 1 Interventional

A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss

NCT07663630
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC), Cachexia
Interventions
ponsegromab, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Decatur, Illinois • O'Fallon, Illinois • Garland, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional

LoveYourBrain Yoga for Multiple Sclerosis

NCT03827928
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Yoga/meditation
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 21, 2026, 10:33 AM EDT
Terminated No phase listed Observational

Characterizing Fatigue Experienced by Registered Nurses

NCT03789188
View directory record Official record
Conditions
Fatigue
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients

NCT02184494
View directory record Official record
Conditions
Parkinson's Disease, Multiple Sclerosis
Interventions
pro5 AIRdaptive Power Plate (Badhoevedorp, The Netherlands)
Device
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 90 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 21, 2026, 10:33 AM EDT
Not listed No phase listed Observational

Discovering Trends in Chronic Fatigue Syndrome Patients' Clinical Study Experiences

NCT05967494
View directory record Official record
Conditions
Chronic Fatigue Syndrome
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 21, 2026, 10:33 AM EDT
Terminated No phase listed Observational

Role of Beta-Endorphin in Cancer Therapy Fatigue

NCT01113905
View directory record Official record
Conditions
Breast Cancer, Fatigue
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder

NCT01254305
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Levomilnacipran ER, Paroxetine, Sertraline, Citalopram or Fluoxetine., Placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 65 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Cerritos, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional

Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment

NCT00565305
View directory record Official record
Conditions
Breast Cancer
Interventions
Healing Touch, Standard Treatment
Behavioral · Radiation
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Phase 4 Interventional

A Placebo-Controlled Trial of Modafinil (Provigil) Added to Clozapine in Patients With Schizophrenia

NCT00573417
View directory record Official record
Conditions
Schizophrenia
Interventions
modafinil, Placebo
Drug
Lead sponsor
North Suffolk Mental Health Association
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

NCT03211689
View directory record Official record
Conditions
Primary Immune Deficiency Disorder, Common Variable Immunodeficiency, Specific Antibody Deficiency, Hypergammaglobulinemia
Interventions
Exercise Program
Other
Lead sponsor
Stockton University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Galloway, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 21, 2026, 10:33 AM EDT
Recruiting Phase 2 Interventional

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

NCT05869682
View directory record Official record
Conditions
Advanced Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Carcinoma, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
Interventions
Bright White Light Therapy, Combination Drug Therapy, Electronic Health Record Review, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Drug · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
60 Years and older · Male only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional

A Study to Compare Two Ways of Completing Pain and Sleep Questions and to Evaluate a New Daily Questionaire for Assessing Fatigue in Fibromyalgia Patients

NCT00819624
View directory record Official record
Conditions
Fibromyalgia
Interventions
Interactive Voice Response System (IVRS), Personal Digital Assisstant (PDA)
Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
15
States / cities
Roseville, California • Baton Rouge, Louisiana • North Dartmouth, Massachusetts + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2010 · Synced Oct 21, 2026, 10:33 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Iron Aid IPS on Performance, Fatigue and Iron Levels During 12 Weeks of Supplementation and Aerobic Training

NCT03523455
View directory record Official record
Conditions
Iron-deficiency
Interventions
Iron Aid IPS (Iron Protein Succinylate), Sugar Pill
Dietary Supplement · Other
Lead sponsor
University of Mary Hardin-Baylor
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of Onnit Alpha Brain on Cognition and Mood States

NCT07495592
View directory record Official record
Conditions
Cognitive, Mood and Cognitive Performance, Sleep Deprivation, Executive Function (Cognition), Fatigue
Interventions
Alpha Brain proprietary cognitive dietary supplement, Alpha Brain 2.0 proprietary cognitive dietary supplement, Controlled Placebo
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
20 Years to 59 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 21, 2026, 10:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Artemis Sleep Countermeasures

NCT06531733
View directory record Official record
Conditions
Fatigue
Interventions
Sleep Promoting (pink noise), Wake Promoting (blue enriched light plus a nap)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline

NCT02785133
View directory record Official record
Conditions
Quality of Life, Fatigue
Interventions
UVL1000 Treatment Station, Normal Saline Solution, Peripheral Catheterization
Device · Drug
Lead sponsor
UVLrx Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
3,063 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Single Group Study to Evaluate the Effects of a Topical Product on Cramps Associated With the Menstrual Cycle

NCT06939972
View directory record Official record
Conditions
Dysmenorrhea, Menstrual Cramps
Interventions
Topical Analgesic with Camphor and Menthol
Dietary Supplement
Lead sponsor
Rael
Industry
Eligibility
18 Years to 35 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional

Efficacy of Massage for the Treatment of Cancer-Related Fatigue (CRF) in Prostate Cancer Survivors

NCT03187275
View directory record Official record
Conditions
Cancer-related Problem/Condition
Interventions
Swedish Massage Therapy, Light Touch Intervention
Other
Lead sponsor
Emory University
Other
Eligibility
45 Years and older · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 21, 2026, 10:33 AM EDT
Active, not recruiting Not applicable Interventional

Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?

NCT05167227
View directory record Official record
Conditions
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection, Post COVID-19 Condition
Interventions
Extension for Community Healthcare Outcomes
Other
Lead sponsor
Family Health Centers of San Diego
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 21, 2026, 10:33 AM EDT
Recruiting No phase listed Observational

Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors

NCT05073848
View directory record Official record
Conditions
Cancer Remission
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Results available

The JustWalk JITAI Study: A System Identification Experiment to Understand Just-in-Time States of Physical Activity

NCT05273437
View directory record Official record
Conditions
Physical Inactivity, Health Behavior, Healthy Lifestyle
Interventions
System identification experiment for physical activity
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Phase 4 Interventional Results available

Modafinil for Treatment of Fatigue in ALS Patients

NCT00614926
View directory record Official record
Conditions
Fatigue
Interventions
Modafinil, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2012 · Synced Oct 21, 2026, 10:33 AM EDT
Terminated Not applicable Interventional

The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease

NCT02885285
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Spinning Class, Yoga Class, Dance Class, No Exercise Class
Behavioral · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 26, 2017 · Synced Oct 21, 2026, 10:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Standing Desks and Intermittent Walking on Cognitive Fatigue

NCT07576413
View directory record Official record
Conditions
Sitting Position, Overexertion From Maintaining Prolonged Standing Position, Walking
Interventions
Performance of cognitive tasks
Behavioral
Lead sponsor
Clarkson University
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Potsdam, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 21, 2026, 10:33 AM EDT