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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fear Anxiety Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Social Support and Enhanced Fear Extinction

NCT04565041
View directory record Official record
Conditions
Fear, Anxiety
Interventions
Social Support
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Memory and Fear Study (Fear of Memory Loss Study)

NCT04821960
View directory record Official record
Conditions
Anxiety and Fear
Interventions
Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Cannabidiol Effects on Learning and Anxiety

NCT05283382
View directory record Official record
Conditions
Anxiety and Fear
Interventions
Cannabidiol Oral Product, Placebo
Drug · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Results available

Treating Phobia With Multivoxel Neuro-reinforcement

NCT03655262
View directory record Official record
Conditions
Phobia
Interventions
Unconscious Neuro-reinforcement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Jul 22, 2026, 10:21 AM EDT
Withdrawn Phase 4 Interventional

Brief Intervention for OCD Fears

NCT02790710
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Propanolol, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 10:21 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Facing Your Fears: Adolescents With ASD and Intellectual Disability

NCT05131425
View directory record Official record
Conditions
Autism Spectrum Disorder, Intellectual Disability, Anxiety, Emotion Regulation
Interventions
Facing Your Fears: ASD/ID, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

NCT05120635
View directory record Official record
Conditions
Fear, GAD, Emotional Memory, PTSD
Interventions
Deep Brain Stimulation, Virtual and augmented reality tasks
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Los Angeles, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Overgeneralization of Conditioned Fear as a Pathogenic Marker of Anorexia Nervosa

NCT02148042
View directory record Official record
Conditions
Anorexia, Generalized Anxiety
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Stress Salivary Biomarkers in Pediatric Patients Undergoing Dental Procedures

NCT06730425
View directory record Official record
Conditions
Dental Anxiety, Dental Fear, Stress, Pediatric Population
Interventions
Not listed
Lead sponsor
Midwestern University
Other
Eligibility
7 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors

NCT05364450
View directory record Official record
Conditions
Breast Neoplasm, Breast Cancer, Breast Carcinoma, Malignant Neoplasm of Breast, Cancer of Breast, Mammary Neoplasms, Human, Human Mammary Carcinoma, Malignant Tumor of Breast, Mammary Cancer, Mammary Carcinoma, Human, Anxiety, Fear
Interventions
Enhanced Usual Care, Acceptance Commitment Therapy, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Jul 22, 2026, 10:21 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Addressing Anxiety in 2-3-Year-Olds: A Pilot Intervention Study

NCT04039243
View directory record Official record
Conditions
Anxiety Disorder of Childhood, Fear, Shyness
Interventions
Being Brave, Parent Education
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Months to 47 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Withdrawn Not applicable Interventional

Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD)

NCT03385317
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Mindfulness
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 27, 2017 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of rTMS on Anxiety

NCT03993509
View directory record Official record
Conditions
Anxiety, Fear, Anxiety and Fear
Interventions
rTMS to the right dlPFC
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety

NCT02810171
View directory record Official record
Conditions
Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Phobia, Agoraphobia, Panic Disorder, Panic Attack, Anxiety
Interventions
Cognitive Behavioral Therapy, Relaxation Therapy
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
7 Years to 17 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fear Conditioning Using Computer-Generated Virtual Reality

NCT00025844
View directory record Official record
Conditions
Anxiety Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 50 Years
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational

Adaptive Care in the Perioperative Setting

NCT03353129
View directory record Official record
Conditions
Development; Delayed, Mental, Anxiety, Situational Anxiety, Fear of Other Medical Care, Behavior, Coping, Behavior Disorders, Psychological Disorder, Behavior Disorders in Children
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Psychopharmacology of Fear-Potentiated Startle in Humans

NCT00044096
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 45 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting No phase listed Observational

Fear and Anxiety in Anesthesia-Naïve Patients Pre-operatively vs Post-operatively

NCT07559461
View directory record Official record
Conditions
Anxiety, Anesthesia Awareness
Interventions
Survey using a questionnaire.
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Withdrawn Not applicable Interventional

Modulating Context Generalization Through Transcranial Direct Current Stimulation

NCT03374605
View directory record Official record
Conditions
Anxiety and Fear
Interventions
active tDCS, sham tDCS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Jul 22, 2026, 10:21 AM EDT
Terminated No phase listed Observational

Social Anxiety Virtual Reality Study

NCT04288180
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
No intervention
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers

NCT06186960
View directory record Official record
Conditions
Hospice, End of Life, Palliative Care, Pain, Anxiety, Fear of Death
Interventions
Tandem Virtual Reality
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seneca, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

School-based Treatment of Anxiety Research Study (STARS)

NCT01761396
View directory record Official record
Conditions
Anxiety Disorders
Interventions
CBT, UC
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
6 Years to 18 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation and Fear Extinction

NCT03907917
View directory record Official record
Conditions
Anxiety Disorders
Interventions
tDCS
Device
Lead sponsor
Thomas Adams
Other
Eligibility
18 Years to 55 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
New Haven, Connecticut • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944
View directory record Official record
Conditions
Depression, Anxiety and Fear
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Jul 22, 2026, 10:21 AM EDT