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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fecal Immunochemical Test Clear all
Terminated Phase 1 Interventional Accepts healthy volunteers

Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam

NCT03013855
View directory record Official record
Conditions
Fecal Immunochemical Test
Interventions
FIT-SOC, FIT-DRE
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional

Incomplete Follow Up After Positive FIT or Stool DNA Testing: A Multimethod Approach

NCT03817905
View directory record Official record
Conditions
Positive FIT or Stool DNA Testing Follow up
Interventions
Patient navigator
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
40 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Colonoscopy Outreach for Rural Communities Aim 2

NCT05453630
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Patient Navigation, Usual Care Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
45 Years to 915 Months
Enrollment
527 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions to Improve Colon Cancer Screening in Poor Rural Iowa Counties

NCT01477814
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Physician chart reminder, chart reminder, educational mat'ls, FIT, CR,ed mat'ls, FIT, phone call
Behavioral
Lead sponsor
Barcey T. Levy
Other
Eligibility
52 Years to 79 Years
Enrollment
743 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 23, 2017 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Behavioral Science to Improve Colorectal Cancer Screening Rates With Mailed FIT Kits

NCT04746469
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Delayed automated phone call
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates

NCT05115916
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
Interventions
MyChart Priming Message
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
51 Years to 75 Years
Enrollment
3,880 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Jul 20, 2026, 1:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES)

NCT03906110
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES) Materials, Contact Message, Personalized One on One Education, Fecal Immunochemical Test (FIT)
Behavioral · Diagnostic Test
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
327 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Jul 20, 2026, 1:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Bundled Cancer Screening and Genetic Services Navigation

NCT07228000
View directory record Official record
Conditions
Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
Interventions
Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral, Pretest education + usual care genetics referral
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
45 Years to 74 Years · Female only
Enrollment
820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Newark, Delaware • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional

Additional Mailed FIT Kits

NCT06805370
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Mailed Additional FIT Kit, Usual Care
Behavioral · Other
Lead sponsor
University of Southern California
Other
Eligibility
60 Years to 74 Years
Enrollment
1,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Letters Promoting Colorectal Cancer Testing

NCT04548765
View directory record Official record
Conditions
Cancer Colorectal
Interventions
Letter, Loss Frame and Fear Appeals, Transparency, Default Effect and Presentation of Alternatives, Enhanced Fear Appeals and Decoy Effect
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
14,644 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Jul 20, 2026, 1:07 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Behavioral Nudge in Colorectal Cancer Screening

NCT06796049
View directory record Official record
Conditions
Improving Fecal Immunochemical Test (FIT) Completion Rates
Interventions
Information pamphlet + social norm driver, Information pamphlet
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial

NCT06822530
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Educational Intervention, Electronic Health Record Review, Interview, Supportive Care, Survey Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
45 Years to 75 Years
Enrollment
682 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional

Geographically Clustered Mailing of Fecal Immunochemical Test (FIT) Kits

NCT03718221
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Usual Care FIT Screening Strategy, GeoMail FIT Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 64 Years
Enrollment
8,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Jul 20, 2026, 1:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening and Risk Factors of Colon Neoplasia

NCT01647776
View directory record Official record
Conditions
Colon Cancer
Interventions
Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
30 Years to 80 Years
Enrollment
3,315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Jul 20, 2026, 1:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)

NCT01239082
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Colonoscopy, FIT
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 75 Years
Enrollment
50,126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2028
U.S. locations
45
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Fresno, California + 42 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional

Randomized Trial of Follow-up to Mailed FIT Kits

NCT06805383
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Phone call, Mailed FIT Kit
Behavioral · Other
Lead sponsor
University of Southern California
Other
Eligibility
45 Years to 59 Years
Enrollment
2,135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Enrolling by invitation Not applicable Interventional

Head to Head Trial of Mailed Cologuard to Mailed FIT

NCT06931860
View directory record Official record
Conditions
Colorectal Cancer Screening, Fecal Immunochemical Test, Multi-target Stool DNA, Colorectal Cancer (CRC)
Interventions
Cologuard, Fecal Immunochemical Test
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 49 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Maximizing Yield of the Fecal Immunochemical Test for Colorectal Cancer Screening

NCT01634126
View directory record Official record
Conditions
Colorectal Cancer
Interventions
1 FIT kit, 2 FIT kit
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
50 Years to 75 Years
Enrollment
2,761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Jul 20, 2026, 1:07 AM EDT
Withdrawn No phase listed Observational

Assessment of Septin9 Biomarker for Detection of Colorectal Cancer in Patients With Positive Fecal Immunochemical Test

NCT01574677
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Not listed
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
49 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Atlanta, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 3, 2014 · Synced Jul 20, 2026, 1:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reminder Modality for CRC Screening

NCT05012007
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Reminder Phone, Reminder Text
Other
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
45 Years to 75 Years
Enrollment
2,653 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Jul 20, 2026, 1:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

mPATH-Cloud for Colorectal Cancer Screening

NCT06441487
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mobile Health Decision Support, Usual care
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
45 Years to 73 Years
Enrollment
1,062 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Recruiting Not applicable Interventional

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

NCT05612347
View directory record Official record
Conditions
Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer, Digestive System Disease
Interventions
FIT, Colonoscopy
Diagnostic Test
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years to 82 Years
Enrollment
8,946 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2035
U.S. locations
18
States / cities
Birmingham, Alabama • Tucson, Arizona • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 20, 2026, 1:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The PRIME-CRC Trial to Promote CRC Screening in Rural Communities

NCT04313114
View directory record Official record
Conditions
Colorectal Cancer
Interventions
health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
45 Years to 75 Years
Enrollment
804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
Bastrop, Louisiana • Marion, Louisiana • Saint Joseph, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Jul 20, 2026, 1:07 AM EDT
Not listed Not applicable Interventional

Augmentation of Screening Colonoscopy With Fecal Immunochemical Testing

NCT00892593
View directory record Official record
Conditions
Colon Cancer
Interventions
Fecal Immunochemical Testing
Device
Lead sponsor
Forsyth Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
3
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Jul 20, 2026, 1:07 AM EDT