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ClinicalTrials.gov public records Last synced Oct 22, 2026, 12:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fine Lines and Wrinkles Clear all

Conditions: Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines, Skin Elasticity, Hair Thinning, Skin Pigmentation, Skin Texture
Interventions: Autologous Adipose Cells Therapy; Biological
Lead sponsor: CERM INC.; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Lewes, Delaware • Newark, Delaware

Conditions: Skin Aging, Skin Wrinkling
Interventions: PrabotulinumtoxinA-Xvfs, IncobotulinumtoxinA, saline solution (placebo); Drug
Lead sponsor: Kalpna Kay Durairaj, MD, FACS; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Pasadena, California

Conditions: Fine Lines and Wrinkles, Skin Health, Skin Tone
Interventions: Light emitting diode treatment; Device
Lead sponsor: Therabody, Inc.; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Purchase, New York

Conditions: Fine Lines, Wrinkles, Laxity; Skin
Interventions: Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30; Other
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Richardson, Texas

Conditions: Wrinkle
Interventions: Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer; Dietary Supplement
Lead sponsor: Saie Beauty; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Fine Lines, Wrinkle, Facial Laxity, Volume Loss
Interventions: Obagi® Saypha® MagIQ™ Injectable Hyaluronic Acid; Other
Lead sponsor: Goldman, Butterwick, Fitzpatrick and Groff; Other
Eligibility: 30 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Wrinkle, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Stretch Mark, Loose Skin
Interventions: RadioFrequency Microneedling Device; Device
Lead sponsor: Cynosure, Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Westford, Massachusetts

Conditions: Fine Lines, Wrinkles, Photoaging
Interventions: Facial cleanser, Facial moisturizer, Sunscreen; Combination Product
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Manhattan Beach, California

Conditions: Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
Interventions: Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30; Other
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Teaneck, New Jersey

Conditions: Fine Lines, Contour, Sagging Skin, Dark Spots, Wrinkles, Firmness, Skin Tone, Radiance/Luminosity
Interventions: LED Light Treatment, Vibration Only; Device
Lead sponsor: Therabody, Inc.; Industry
Eligibility: 35 Years to 65 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Piscataway, New Jersey

Conditions: Photoaging, Wrinkle, Sun Damaged Skin
Interventions: Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug); Combination Product
Lead sponsor: Vitality Institute Medical Products; Industry
Eligibility: 30 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Rancho Mirage, California

Conditions: Skin
Interventions: Lumenato; Dietary Supplement
Lead sponsor: LycoRed Ltd.; Industry
Eligibility: 35 Years to 55 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fairfield, New Jersey

Conditions: Wrinkle, Photoaging, Acne, Skin Inflammation
Interventions: Aria Trio complete Facial System; Other
Lead sponsor: Trophy Skin; Industry
Eligibility: 25 Years to 65 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Wrinkle, Photoaging, Fine Lines
Interventions: Gentle Cleansing Lotion, Revision Skincare, Aveeno Face Milk SPF 40+; Other
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 65 Years · Female only
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Richardson, Texas

Conditions: Wrinkle, Fine Lines, Crepey Skin, Acne Scars, Acne, Enlarged Pores, Stretch Marks, Loose Skin
Interventions: Potenza; Device
Lead sponsor: Cynosure, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 4
States / cities: Sacramento, California • Hunt Valley, Maryland • Westford, Massachusetts + 1 more

Conditions: Wrinkles, Photoaging, Fine Lines
Interventions: Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer, Sunscreen; Procedure · Combination Product
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Fort Lauderdale, Florida • Coralville, Iowa • Columbus, Ohio

Conditions: Wrinkle
Interventions: Skinvive; Device
Lead sponsor: Goldman, Butterwick, Fitzpatrick and Groff; Other
Eligibility: 25 Years to 50 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Wrinkle, Elastic Skin, Collagen Degeneration
Interventions: Straberi Epistamp Microneedling Treatment; Device
Lead sponsor: Universal Skincare Institute; Other
Eligibility: 21 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
Interventions: Gentle Cleansing Lotion, Revision Skincare; Other
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Solana Beach, California • Greenwood Village, Colorado • Nashville, Tennessee

Conditions: Wrinkles, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Loose Skin
Interventions: RF Device (Potenza™); Device
Lead sponsor: Cynosure, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: West Hollywood, California

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Autologous Adipose Cells Therapy

Effects of Microtox on Facial Skin Quality, Fine Wrinkles, and Texture

Efficacy of an LED Mask

A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation

Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections

Assess Injectable Hyaluronic Acid Gel for the Treatment of Volume Loss, Skin Laxity and Fine Lines

Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions

A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines

A 12 Week Study to Evaluate the Efficacy of an Eye Cream

Evaluation of the Efficacy of a Cosmetic Light Mask

Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles

A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects

An Exploratory Investigation of a Novel Skincare Regimen

An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream

Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions

Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines

Assess Impact of Microdroplet Hyaluronic Acid Filler on Skin Quality in Patients on Glucagon-like Peptide-1 Agonists

Straberi Epistamp Needling Treatment For Skin Rejuvenation

A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging

Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device