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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:04 AM EDT

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Showing 1–24 of 60 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Firefighter Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Pre-malignant States to Hematologic Malignancies in Firefighters

NCT06870760
View directory record Official record
Conditions
Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder
Interventions
Monoclonal Gammopathy, Complete Blood Count with differential (CBC w/ diff), Clonal hematopoiesis (CHIP)
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 49 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Rapid Heat Stress on Firefighters Musculoskeletal Injury Risk

NCT06442956
View directory record Official record
Conditions
Occupational Injuries, Heat Stress, Leg Injury, Back Injuries
Interventions
Rapid Heat Condition, Gradual Heat Condition
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 57 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Cognitive Training for Firefighters With Tinnitus

NCT01458821
View directory record Official record
Conditions
Tinnitus
Interventions
Brain Fitness Program - Tinnitus
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 18, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Pork Protein on Recovery Following Simulated Fireground Activity

NCT07819565
View directory record Official record
Conditions
Exercise Recovery, Physical Performance Parameters, Muscle Damage, Cognition, Blood Biomarkers, Stress
Interventions
Pork-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals, Carbohydrate-Focused Lower-Protein Ready-to-Eat Meals
Other
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Fort Worth, Texas • Huntsville, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise & Diet Effects on CV Risk in Firefighters

NCT03344198
View directory record Official record
Conditions
Cardiovascular Risk Factor, Blood Pressure, Exercise, Diet Modification, Health Promotion
Interventions
Circuit Training exercise & Modified Mediterranean diet
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Oct 18, 2026, 2:04 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Firefighter Collaborative Research Project

NCT05869747
View directory record Official record
Conditions
Exposure, Cardiopulmonary
Interventions
Blood Donation, Plasma Donation, Zone 2 Training, Intermittent Fasting, Surveys
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
7
States / cities
Gilbert, Arizona • Green Valley, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementing Good Nutrition to Improve, Transform, and Enhance (IGNITE) Firefighters' Health

NCT06567561
View directory record Official record
Conditions
Cancer, Inflammation, Microbiome, Immune Function
Interventions
Whole Foods Plant-Based Diet, Usual Firehouse Diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The Impact of Self-assessment on Hydration

NCT06954909
View directory record Official record
Conditions
Hydration Status
Interventions
Hydration education and self-assessment
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities

NCT07822048
View directory record Official record
Conditions
Physical Performance Parameters, Exercise Recovery, Cognition, Muscle Damage, Blood Biomarkers, Stress
Interventions
Beef-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals
Other
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Fort Worth, Texas • Huntsville, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

NCT06042270
View directory record Official record
Conditions
Body Temperature Changes, Body Water Dehydration, Inflammation
Interventions
Betaine, Placebo
Dietary Supplement
Lead sponsor
Michael J. Ormsbee
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 18, 2026, 2:04 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Observational Study of Exposure to Environmental Toxicants Among Firefighters

NCT05643014
View directory record Official record
Conditions
Healthy
Interventions
Sample collection
Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters

NCT07846371
View directory record Official record
Conditions
Environmental Exposure, PFAS Exposure
Interventions
Streptococcus salivarius 46-SL1, Placebo
Dietary Supplement
Lead sponsor
Cambiotics ApS
Industry
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Influence of a Corrective Exercise Training Program on Measures of Functional Movement Among Active-Duty Firefighters

NCT02672735
View directory record Official record
Conditions
Functional Movement Quality
Interventions
Corrective Exercise Programming
Other
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2016 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Nutritional Supplementation on Occupational Performance in Firefighters

NCT06172543
View directory record Official record
Conditions
Fatigue
Interventions
Creatine Monohydrate, Control
Dietary Supplement
Lead sponsor
Ward Dobbs
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First Twenty for Volunteer Firefighters

NCT03181321
View directory record Official record
Conditions
Obesity, Cardiovascular Diseases, Occupational Injuries
Interventions
The First Twenty
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
419 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EaseAlert: Tactile Firefighter Alerting System

NCT05641194
View directory record Official record
Conditions
Heart Rate, Sleep Habit, Sleep
Interventions
Legacy Alerting System, Intervention 2: EaseAlert Standalone
Device
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Blue Springs, Missouri • Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation

NCT01066923
View directory record Official record
Conditions
Heat Stress Disorders
Interventions
Daily aspirin (ASA), Active cooling, Acute aspirin (ASA), Passive cooling, Daily placebo, Acute placebo
Drug · Other
Lead sponsor
Dave Hostler
Other
Eligibility
18 Years to 49 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Phase 3 Interventional Results available

Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)

NCT00860847
View directory record Official record
Conditions
Coronary Atherosclerosis, Coronary Artery Calcification, Coronary Stenosis
Interventions
Aged garlic extract and Coenzyme Q10
Dietary Supplement
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
35 Years to 84 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2015 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits

NCT02941757
View directory record Official record
Conditions
Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
Interventions
Mediterranean diet Intervention
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years and older
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Train-the-Trainer Delivered Exercise Intervention in Firefighters

NCT05287594
View directory record Official record
Conditions
Firefighter, High Intensity Interval Training
Interventions
Integrated Exercise Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smokeless Tobacco Cessation Intervention for Firefighters

NCT05111041
View directory record Official record
Conditions
Smokeless Tobacco Cessation
Interventions
#EnufSnuff.TXT- First Responder, Enough Snuff Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First 20 Fire Academy Recruits Exercise Training Program

NCT03319394
View directory record Official record
Conditions
Physical Fitness
Interventions
The First Twenty, Comparison
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 18, 2026, 2:04 AM EDT
Recruiting Phase 1Phase 2 Interventional

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

NCT07226440
View directory record Official record
Conditions
Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
Interventions
Colesevelam, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 18, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Study of Cognitive Behavioral Therapy - Insomnia (CBT-I) Among Professional Firefighters

NCT05087121
View directory record Official record
Conditions
Insomnia, Shift-Work Related Sleep Disturbance
Interventions
Cognitive Behavioral Therapy for Insomnia for Firefighters (CBT-I-F), Fitbit Inspire HR Wrist Worn Device (NCT04176926)
Behavioral · Device
Lead sponsor
Pacific University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Forest Grove, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Oct 18, 2026, 2:04 AM EDT