- Conditions
- Psychosis, First Episode Psychosis, Clinical High Risk for Psychosis
- Interventions
- Not listed
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 15 Years to 30 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
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Showing 1–24
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- Conditions
- First-Episode Psychosis
- Interventions
- Financial Incentive and Text-Messages
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 3
- States / cities
- Raleigh, North Carolina • Philadelphia, Pennsylvania • Philadephia, Pennsylvania
- Conditions
- Schizophrenia
- Interventions
- Cognitive remediation training (CT), Healthy behavior training (HBT), Risperidone, administered orally (Oral Ris), Risperidone, administered via injection (RLAI)
- Behavioral · Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2013
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Clinical High Risk, Early Psychosis, First Episode Psychosis
- Interventions
- Digital nudge
- Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 12 Years to 29 Years
- Enrollment
- 25,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder Not Otherwise Specified
- Interventions
- long-acting injectable risperidone
- Drug
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 15 Years to 40 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2013
- U.S. locations
- 2
- States / cities
- Brooklyn, New York • Glen Oaks, New York
- Conditions
- Schizophrenia, Psychotic Disorders, Mental Health, Mental Disorders
- Interventions
- Olanzapine, risperidone
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 16 Years to 40 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2005
- U.S. locations
- 24
- States / cities
- Stanford, California • Miami, Florida • Atlanta, Georgia + 21 more
- Conditions
- Schizoaffective Disorders, Bipolar Disorder With Psychotic Features, Schizophrenia Disorders, Major Depressive Disorder With Psychotic Features, Psychosis NOS
- Interventions
- Transition Care Team
- Behavioral
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Harvey, Illinois
- Conditions
- Psychotic Disorders, Schizophrenia
- Interventions
- Graduated Recovery Intervention Program (GRIP), Treatment as usual (TAU)
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Schizophrenia, Schizoaffective Disorder, Depressive Type, Schizophreniform Disorder
- Interventions
- Aripiprazole Lauroxil, ARI-ORAL, AL-NCD
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Interventions
- Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST), Chorus Participatory Text Messaging Program, Healthy Living Group (HLG)
- Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Schizophrenia (Recent-onset)
- Interventions
- paliperidone palmitate, risperidone
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 146 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2021
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- First Episode Psychosis (FEP), Clinical High Risk for Psychosis (CHR)
- Interventions
- Screening Method (SM), Screening and Communication Method (SCM)
- Behavioral
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 12 Years to 30 Years
- Enrollment
- 912 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorder, Unspecified or Other Psychotic Disorders
- Interventions
- Horyzons USA
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Psychosis, Schizophrenia, First-episode Psychosis
- Interventions
- Normobaric Oxygen, Placebo
- Device
- Lead sponsor
- Nicholas Breitborde
- Other
- Eligibility
- 15 Years to 35 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Schizophrenia
- Interventions
- I-CAT Therapy
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Schizophrenia, Psychosis, Schizoaffective Disorder, Schizophreniform Disorders, Psychosis NOS, Depression Psychotic Feature, Bipolar Disorder With Psychotic Features, Unspecified Psychosis
- Interventions
- Targeted Cognitive Training, General Cognitive Exercises, Coordinated Specialty Care for First Episode Psychosis
- Device · Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Schizophrenia, First-Episode Psychosis
- Interventions
- mHealth Intervention
- Other
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 16 Years to 30 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 4
- States / cities
- Buffalo, New York • New York, New York
- Conditions
- Bipolar I Disorder, Schizoaffective Disorder, Psychosis
- Interventions
- Ketogenic diet
- Other
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Schizophrenia
- Interventions
- Any FDA approved antipsychotic agent, aripiprazole long acting injectable formulation
- Drug
- Lead sponsor
- Vanguard Research Group
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 489 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 39
- States / cities
- Tucson, Arizona • Granada Hills, California • Palo Alto, California + 35 more
- Conditions
- Psychosis, Schizoaffective Disorder, Schizophrenia
- Interventions
- OnTrack>TheGame (OTG), Recovery Videos (RV)
- Behavioral
- Lead sponsor
- Center for Social Innovation, Massachusetts
- Other
- Eligibility
- 16 Years to 30 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- First Episode Psychosis, Schizophrenia
- Interventions
- Social Network Meetings
- Behavioral
- Lead sponsor
- Lisa Dixon
- Other
- Eligibility
- 16 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Yonkers, New York
- Conditions
- Schizophrenia
- Interventions
- Clozapine, Haloperidol
- Drug
- Lead sponsor
- Harvard Medical School (HMS and HSDM)
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 2003
- U.S. locations
- 1
- States / cities
- Jamaica Plain, Massachusetts
- Conditions
- First Episode Psychosis
- Interventions
- Stakeholder feedback, Data infrastructure
- Other
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 2,100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia
- Interventions
- Neuroadaptive cognitive training, Computer games
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 12 Years to 35 Years
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2015
- U.S. locations
- 2
- States / cities
- Sacramento, California • San Francisco, California