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ClinicalTrials.gov public records Last synced Sep 13, 2026, 6:38 PM EDT

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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: First Responders Clear all
Not listed No phase listed Observational Accepts healthy volunteers

COVID-19 CHAMPS Study of Healthcare, First Responder and Service Workers

NCT04370821
View directory record Official record
Conditions
Occupational Exposure to SARS-CoV-2, COVID-19
Interventions
Not listed
Lead sponsor
Villanova University
Other
Eligibility
18 Years and older
Enrollment
2,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Villanova, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Heroes Study

NCT03533023
View directory record Official record
Conditions
Shift Workers' Health, Time Restricted Eating, Fasting
Interventions
Time Restricted Eating + Standard of Care, Standard of Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 13, 2026, 6:38 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Will Hydroxychloroquine Impede or Prevent COVID-19

NCT04341441
View directory record Official record
Conditions
COVID-19, Coronavirus, Coronavirus Infections, SARS-CoV 2
Interventions
Hydroxychloroquine - Daily Dosing, Hydroxychloroquine - Weekly Dosing, Placebo oral tablet, Monitoring Visit - Baseline, Monitoring Visit - Week 4, Monitoring Visit - Week 8, Weekly Assessment
Drug · Other · Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 75 Years
Enrollment
624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Determine the Most Effective Intervention for Hemorrhage Control Readiness for Laypersons: The PATTS Trial

NCT03479112
View directory record Official record
Conditions
Traumatic Hemorrhage
Interventions
Flashcards, Audio-kit, B-Con training, B-Con training retention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional

eTMS for Veterans and First Responders With PTSD

NCT06294106
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Electroencephalogram personalized Transcranial Magnetic Stimulation (eTMS)
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Not applicable Interventional

Online Therapy for Posttraumatic Stress Symptoms in WTC Responders and Survivors

NCT03154151
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Online Cognitive-Behavioral Therapy, Online Supportive Therapy
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
New Haven, Connecticut • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional

Evaluating Evidenced Based Options for PTSD Treatment

NCT06733376
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 13, 2026, 6:38 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effects of Stress & Irregular Shift Hours on First Responders

NCT05659277
View directory record Official record
Conditions
Workplace Stress, Mental Health, HRV, EEG, PTSD
Interventions
Workplace Stress and Irregular shift hours
Other
Lead sponsor
Endominance
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Phase 2 Interventional Results available

Response Adapted Therapy With Bortezomib/Dexamethasone Followed by Addition of Lenalidomide in Non Responders as Initial Treatment for Patients With Multiple Myeloma

NCT01919086
View directory record Official record
Conditions
Multiple Myeloma (MM)
Interventions
Bortezomib, Dexamethasone, Lenalidomide
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
7
States / cities
Hartford, Connecticut • Basking Ridge, New Jersey • Middletown, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Not yet recruiting No phase listed Observational

Using Integrated Care and Wearable Technology to Evaluate Outcomes of the Shields & Stripes Program for Veterans and First Responders

NCT07452900
View directory record Official record
Conditions
Holistic Care, Mental Health, Sleep, PTSD, Depression - Major Depressive Disorder, Anxiety, Resilience, Recovery, Occupation, Biometrics Measurement, Veteran, Quality of Life
Interventions
Not listed
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Not applicable Interventional

Recovery Initiation and Management After Overdose (RIMO) Experiment

NCT03895827
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Recovery Initiation and Management after Overdose (RIMO), Passive Referral to Treatment Control
Behavioral · Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Active, not recruiting Phase 2 Interventional

PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

NCT06853912
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
Psilocybin 25 mg, Maltodextrin (Placebo)
Drug
Lead sponsor
Nathan Brashares Sackett
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional

First Responder Airway & Compression Rate Trial

NCT05969028
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest
Interventions
igel, Compression Rate
Device · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
4,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional

tAN for First Responders

NCT07109349
View directory record Official record
Conditions
Mental Fatigue, Mental Stress
Interventions
Sparrow Link
Device
Lead sponsor
Spark Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional

EEG-based Personalized Transcranial Magnetic Stimulation (eTMS) to Treat Post-Traumatic Stress Disorder

NCT06892028
View directory record Official record
Conditions
Stress Disorder, Post Traumatic
Interventions
EEG-based personalized TMS, Sham Comparator
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
22 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Dayton, Ohio • Pickerington, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 13, 2026, 6:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Function and Oxidative Stress in Emergency Medical Responders

NCT06985394
View directory record Official record
Conditions
Cardiovascular Function in EMTs
Interventions
Antioxidant cocktail, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 13, 2026, 6:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Heartmatters Challenge - First Responders

NCT03322046
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Lifestyle Program
Behavioral
Lead sponsor
Boston Heart Diagnostics
Industry
Eligibility
18 Years to 65 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States

NCT06633835
View directory record Official record
Conditions
COVID-19, Vaccine-Preventable Diseases, SARS CoV 2 Infection
Interventions
protein subunit: Novavax COVID-19 vaccine, Pfizer mRNA COVID-19 vaccine
Biological
Lead sponsor
Novavax
Industry
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 13, 2026, 6:38 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Testing a Novel Attention Based Training Prevention Strategy for First Responders: FirstFocus a Mobile App

NCT07247149
View directory record Official record
Conditions
Wellbeing
Interventions
Attention Bias Modification
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 13, 2026, 6:38 PM EDT
Completed Not applicable Interventional Results available

EEG Personalized Transcranial Magnetic Stimulation (eTMS) for Post-Traumatic Stress Disorder

NCT06081309
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
EEG-based personalized TMS
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
22 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 13, 2026, 6:38 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Daily Coping Toolkit for Medical Personnel and First-Responders During COVID-19 Pandemic

NCT04398277
View directory record Official record
Conditions
Psychological Stress
Interventions
Daily Coping Toolkit
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Akron, Ohio • Kent, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 13, 2026, 6:38 PM EDT
Enrolling by invitation Not applicable Interventional

Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida

NCT06648928
View directory record Official record
Conditions
PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
Interventions
Clinician Supported PTSD Coach, Self Managed PTSD Coach
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 13, 2026, 6:38 PM EDT