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Showing 25–47 of 23 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: First Trimester Abortion Clear all
Completed Phase 4 Interventional Results available

Evaluation of Oral Midazolam in First-trimester Surgical Abortions

NCT01830881
View directory record Official record
Conditions
Pain, Anxiety, Nausea
Interventions
Midazolam, Ibuprofen, Placebo-Cherry syrup, Lidocaine
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 24, 2018 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions

NCT02756403
View directory record Official record
Conditions
First Trimester Abortion
Interventions
Azithromycin, Doxycycline, Metronidazole, Placebo
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 4 Interventional Results available

Hydrocodone For Pain Control in First Trimester Surgical Abortion

NCT01330459
View directory record Official record
Conditions
Pain
Interventions
Hydrocodone/acetaminophen, Placebo, Ibuprofen, Lorazepam, Lidocaine
Drug
Lead sponsor
Elizabeth Micks
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion

NCT05320432
View directory record Official record
Conditions
Abortion in First Trimester, Pain
Interventions
Transcutaneous electrical nerve stimulation (TENS), Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Refining Paracervical Block Techniques for Pain Control in First Trimester Surgical Abortion

NCT01466491
View directory record Official record
Conditions
Pain
Interventions
Paracervical block technique with lidocaine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Immediate Start of Progestin Contraceptives in Medical Abortion

NCT01902485
View directory record Official record
Conditions
Contraception
Interventions
Timing of Contraceptive Initiation in Medical Abortion
Other
Lead sponsor
Gynuity Health Projects
Other
Eligibility
Female only
Enrollment
937 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
6
States / cities
Chula Vista, California • Eureka, California • Stamford, Connecticut + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

CCT-102 or Expectant Management in Delayed Pregnancy Loss

NCT06121063
View directory record Official record
Conditions
Early Pregnancy Loss, Delayed Pregnancy Loss
Interventions
CCT-102 A and CCT-102 B
Combination Product
Lead sponsor
Conceptra Biosciences, LLC
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
15
States / cities
Tucson, Arizona • San Fernando, California • Panama City, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 22, 2026, 10:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Understanding Women's Contraceptive Expectations at the Time of a First Trimester Surgical Abortion

NCT01807715
View directory record Official record
Conditions
Contraception, Abortion
Interventions
survey
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 10:39 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)

NCT00337792
View directory record Official record
Conditions
Undesired Pregnancy
Interventions
oxycodone + lorazepam versus fentanyl + midazolam
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Jul 22, 2026, 10:39 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion

NCT03508804
View directory record Official record
Conditions
Pain
Interventions
Lidocaine-Prilocaine Cream, Placebo Cream, 1% Lidocaine Paracervical Block
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Paracervical Block in First Trimester Surgical Abortions

NCT00617097
View directory record Official record
Conditions
Pain, Surgical Abortion
Interventions
lidocaine, ketorolac and lidocaine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality Experience in First Trimester D&C

NCT03533036
View directory record Official record
Conditions
First Trimester Abortion, Virtual Reality
Interventions
applied VR headset
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Jul 22, 2026, 10:39 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions

NCT01011634
View directory record Official record
Conditions
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Interventions
Intravenous moderate sedation versus oral medication
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lidocaine and Pain Management in First Trimester Abortions

NCT00613821
View directory record Official record
Conditions
Pain
Interventions
Lidocaine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT03925129
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
high frequency TENS treatment, Sham TENS treatment
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Jul 22, 2026, 10:39 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks

NCT05119439
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone + 2 doses of misoprostol 800 mcg
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 55 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Hilo, Hawaii • Honolulu, Hawaii • Saint Paul, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Jul 22, 2026, 10:39 AM EDT
Recruiting Not applicable Interventional

Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion

NCT07288047
View directory record Official record
Conditions
Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction, Satisfaction With Care, Anxiety After Surgery
Interventions
VR headset, Usual Care
Device · Other
Lead sponsor
Study Investigator
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 22, 2026, 10:39 AM EDT
Completed No phase listed Observational

Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia

NCT00583635
View directory record Official record
Conditions
Preeclampsia, Pregnancy Loss
Interventions
Not listed
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of an Algorithm to Determine IV Sedation Dosing During First-trimester Surgical Abortion

NCT01994317
View directory record Official record
Conditions
Pregnancy, Unplanned
Interventions
Algorithm, Standard care
Other
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2015 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Misoprostol for Non-Viable Pregnancies

NCT00426491
View directory record Official record
Conditions
Abortifacient Agents, Nonsteroidal, Abortion, Incomplete, Misoprostol, Pregnancy
Interventions
Misoprostol
Drug
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2006
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2008 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional

Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks

NCT03079622
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Electric Vacuum Aspiration, Manual Vacuum Aspiration
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Not applicable Interventional

Non-Pharmacologic Patient Centered Pain Control Adjuncts During First Trimester Abortion

NCT02590146
View directory record Official record
Conditions
Pregnancy Termination, Pain Management
Interventions
Non-pharmacologic pain control adjuncts
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Jul 22, 2026, 10:39 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion

NCT03480009
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Dextromethorphan Hydrobromide, Avicel PH101 (Microcrystalline Cellulose NF) for Compounding, Oxycodone
Drug
Lead sponsor
Study Investigator-Sponsor
Other
Eligibility
18 Years and older · Female only
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Jul 22, 2026, 10:39 AM EDT