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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: First Trimester Pregnancy Clear all
Completed No phase listed Observational Accepts healthy volunteers

Assessment of the Number of Umbilical Cord Vessels at the Time of Nuchal Translucency Screening

NCT01367132
View directory record Official record
Conditions
Umbilical Cord
Interventions
Doppler ultrasound
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Jul 21, 2026, 5:31 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion

NCT03508804
View directory record Official record
Conditions
Pain
Interventions
Lidocaine-Prilocaine Cream, Placebo Cream, 1% Lidocaine Paracervical Block
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Blood Loss at the Time of First Trimester Surgical Abortion in Anticoagulated Women

NCT00614432
View directory record Official record
Conditions
Blood Loss
Interventions
Not listed
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Honolulu, Hawaii • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 17, 2022 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional Results available

Hydrocodone For Pain Control in First Trimester Surgical Abortion

NCT01330459
View directory record Official record
Conditions
Pain
Interventions
Hydrocodone/acetaminophen, Placebo, Ibuprofen, Lorazepam, Lidocaine
Drug
Lead sponsor
Elizabeth Micks
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acupuncture for Pain Management During Uterine Aspiration

NCT03391986
View directory record Official record
Conditions
Pain Acute, Acupuncture
Interventions
SEIRIN® Pyonex™ Acupuncture Needles, 12 mm Plasters
Device · Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational

First Trimester Prediction of Preeclampsia and Fetal Growth Restriction

NCT02379494
View directory record Official record
Conditions
Preeclampsia, Fetal Growth Restriction
Interventions
Not listed
Lead sponsor
Fetal Medicine Foundation
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions

NCT01011634
View directory record Official record
Conditions
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Interventions
Intravenous moderate sedation versus oral medication
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality Experience in First Trimester D&C

NCT03533036
View directory record Official record
Conditions
First Trimester Abortion, Virtual Reality
Interventions
applied VR headset
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Refining Paracervical Block Techniques for Pain Control in First Trimester Surgical Abortion

NCT01466491
View directory record Official record
Conditions
Pain
Interventions
Paracervical block technique with lidocaine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage

NCT01595282
View directory record Official record
Conditions
Pain
Interventions
Ketorolac, Ibuprofen
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Versus Intracervical Lidocaine

NCT00816751
View directory record Official record
Conditions
Abortion, Induced, Pain
Interventions
Paracervical block, Intracervical, Buffered Lidocaine, vasopressin, sodium bicarbonate
Procedure · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)

NCT00337792
View directory record Official record
Conditions
Undesired Pregnancy
Interventions
oxycodone + lorazepam versus fentanyl + midazolam
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Iron Parameters in Non-anemic First Trimester Gravidas

NCT03670537
View directory record Official record
Conditions
Iron Deficiency (Without Anemia), Pregnancy
Interventions
Iron parameters
Diagnostic Test
Lead sponsor
Auerbach Hematology Oncology Associates P C
Other
Eligibility
Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Use of Music for Pain and Anxiety Control During Abortion

NCT01013363
View directory record Official record
Conditions
Pain, Anxiety
Interventions
iPod Nano digital music player
Other
Lead sponsor
Columbia University
Other
Eligibility
Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2012 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)

NCT01549587
View directory record Official record
Conditions
Gingivitis, Pregnancy
Interventions
0.243% sodium fluoride, toothbrush, dental floss, 0.454% stannous fluoride, 0.07% Cetylpyridinium chloride
Drug · Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older · Female only
Enrollment
746 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Birmingham, Alabama • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT03925129
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
high frequency TENS treatment, Sham TENS treatment
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial

NCT02447029
View directory record Official record
Conditions
Pregnancy, Unwanted
Interventions
vaginal 2% Xylocaine, standard lidocaine paracervical block
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management of First Trimester Surgical Abortion

NCT02096575
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Nitrous oxide administration
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Randomized Study of Cervical Priming With Misoprostol Prior to Elective First Trimester Pregnancy Termination

NCT00310921
View directory record Official record
Conditions
Abortion, Therapeutic
Interventions
Misoprostol
Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2007 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional Results available

Pain Control In First Trimester Medical Abortion: A Randomized Trial

NCT01457521
View directory record Official record
Conditions
Pain
Interventions
Ibuprofen
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Paracervical Block for Pain Control in First Trimester Abortion

NCT01094366
View directory record Official record
Conditions
Legal Abortion With Complication, Pain
Interventions
Paracervical Block, Sham Paracervical Block
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Performance Evaluation of the Artificial Intelligence (AI)/ Machine Learning (ML) Technologies Utilized by the Origin Medical EXAM ASSISTANT

NCT06952439
View directory record Official record
Conditions
To Validate the Clinical Performance of AI/ML Technologies in First-trimester Pregnant Participants, First Trimester Pregnancy
Interventions
Images and cines captured through the capture card (ICC)
Device
Lead sponsor
Origin Medical Systems, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
551 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
15
States / cities
Apple Valley, California • Indio, California • Murrieta, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Educating Women About Pelvic Floor Disorders During Pregnancy

NCT05440539
View directory record Official record
Conditions
Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Written Handouts, Interactive Workshop
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational

Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia

NCT00583635
View directory record Official record
Conditions
Preeclampsia, Pregnancy Loss
Interventions
Not listed
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Jul 21, 2026, 5:31 PM EDT