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ClinicalTrials.gov public records Last synced Sep 16, 2026, 2:42 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Flap Reconstruction Clear all
Completed Not applicable Interventional Results available

Robotic Harvest of the Latissimus Dorsi (LD) Muscles

NCT02274493
View directory record Official record
Conditions
Other Reconstructive Surgery, Failure of Muscle Graft, Cancer, Complications, Surgical Procedure, Unspecified
Interventions
da Vinci® Robotic Surgical System, LD muscle flap harvest procedure, Reconstructive surgery, Questionnaires
Device · Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional

Feasibility and Safety of Single-Port Robotic-Assisted Deep Inferior Epigastric Pedicle Flap Harvest

NCT07222514
View directory record Official record
Conditions
DIEP Flap Breast Reconstruction
Interventions
Single-Port Robotic System
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional

WashU DIEP Flap Video and Patient Understanding Improvement

NCT06864754
View directory record Official record
Conditions
Breast Cancer
Interventions
WashU DIEP Flap Video
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 16, 2026, 2:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Intraoperative Pathway in DIEP Flap Breast Reconstruction

NCT00543764
View directory record Official record
Conditions
Breast Cancer
Interventions
pathway
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 16, 2026, 2:42 PM EDT
Not listed Not applicable Interventional

The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability

NCT01554267
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Mastectomy
Interventions
Laser-Assisted ICG Dye Angiography (SPY System)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2014 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Early Phase 1 Interventional

Objective Flap Assessment During Reconstructive Surgery

NCT00952107
View directory record Official record
Conditions
Cancer
Interventions
FLARE imaging system
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Sep 16, 2026, 2:42 PM EDT
Active, not recruiting Not applicable Interventional

A Study of Near-Infrared Fluorescence Imaging With ICG During Reconstructive Gynecologic Surgery

NCT05071976
View directory record Official record
Conditions
Gynecologic Surgery
Interventions
ICG-NIR angiography
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 16, 2026, 2:42 PM EDT
Withdrawn Not applicable Interventional

Integrated Imaging System for In Vivo Visualization of Free Flap Perfusion Using Indocyanine Dye

NCT03625765
View directory record Official record
Conditions
Breast Reconstruction
Interventions
SmartGoggles
Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Phase 4 Interventional

Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction

NCT01258296
View directory record Official record
Conditions
Postoperative Pain After Breast Reconstruction With Abdominal Flap
Interventions
Fentanyl, Inactive patch
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Phase 1 Interventional

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

NCT07264790
View directory record Official record
Conditions
Breast Reconstruction, Perfusion; Complications, High Risk for Breast Cancer, Genetic Predisposition
Interventions
Minoxidil, Hair mousse
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 16, 2026, 2:42 PM EDT
Terminated Not applicable Interventional

Sensory Restoration After DIEP Flap Neurotization

NCT04533373
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Sensory Restoration
Interventions
DIEP Flap Neurotization
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting No phase listed Observational

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

NCT04098146
View directory record Official record
Conditions
Mandibular Reconstruction, Segmental Mandibular Defects
Interventions
Surgical Resection and Reconstruction
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2022 – 2030
U.S. locations
5
States / cities
Jacksonville, Florida • Chicago, Illinois • New Hyde Park, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Phase 3 Interventional Results available

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

NCT02601027
View directory record Official record
Conditions
Breast - Female
Interventions
Transversus Abdominis Plane (TAP) block, Nimbus Infusion Pump IV Administration, Bupivacaine infusion, Acetominophen, Hydromorphone, Oxycodone, Ondansetron
Procedure · Device · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Sep 16, 2026, 2:42 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Regional Anesthesia Block in Fibula Free Flap Reconstruction

NCT03906838
View directory record Official record
Conditions
Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative, Head and Neck Neoplasms
Interventions
Ropivacaine injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Phase 1 Interventional

Topical CBD Scar Healing Study

NCT06129591
View directory record Official record
Conditions
Paramedian Forehead Flap
Interventions
Vantage Hemp CBD Isolate + Silicone patch, Silicone patch
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 16, 2026, 2:42 PM EDT
Withdrawn No phase listed Observational

Mohs Micrographic Surgery and Reconstruction in the Optum Insurance Claims Database

NCT04117373
View directory record Official record
Conditions
Skin Cancer, Mohs Micrographic Surgery, Interpolated Flap Repair
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Year to 99 Years
Timeline
2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction

NCT04777591
View directory record Official record
Conditions
Postoperative Pain, Breast Reconstruction
Interventions
Liposomal bupivacaine TAP block, Bupivacain
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 16, 2026, 2:42 PM EDT
Not listed No phase listed Observational

Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03872544
View directory record Official record
Conditions
Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds and Injuries, Wounds, Disturbance of Wound Healing, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Phase 4 Interventional Results available

Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management

NCT04284930
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Depobupivacaine, OnQ pump, 0.25% Bupivacaine
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

NCT04003038
View directory record Official record
Conditions
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
Interventions
Negative Pressure Wound Therapy, Wound Care Management
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 16, 2026, 2:42 PM EDT
Not yet recruiting Not applicable Interventional

ORASIS in Breast Reconstruction

NCT07670754
View directory record Official record
Conditions
DIEP Flap, Breast Reconstruction, Breast Cancer
Interventions
Use of ORASIS Device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 16, 2026, 2:42 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050
View directory record Official record
Conditions
Perfusion; Complications
Interventions
Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg), No treatment
Drug · Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 16, 2026, 2:42 PM EDT
Completed Not applicable Interventional

CT-Angiography Prior to DIEP Flap Breast Reconstruction

NCT02883387
View directory record Official record
Conditions
Breast Cancer
Interventions
Preoperative CT angiography, No Preoperative Imaging
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Sep 16, 2026, 2:42 PM EDT
Recruiting Phase 4 Interventional

Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction

NCT06784999
View directory record Official record
Conditions
Free Flap Reconstruction
Interventions
sufentanil, methadone
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 16, 2026, 2:42 PM EDT