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Showing 1–24 of 81 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Flexibility Clear all
Completed No phase listed Observational Accepts healthy volunteers

Impact of Metabolic Flexibility on Changes in Metabolic Health

NCT06340321
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Metabolic flexibility in the fasted state, Metabolic flexibility in euglycemic-hyperinsulinemic clamp, Metabolic flexibility in the metabolic chamber
Diagnostic Test · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Jul 21, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility

NCT07217652
View directory record Official record
Conditions
Schizophrenia, Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions
High-resolution fMRI during working memory, cognitive control, and decision-making tasks
Other
Lead sponsor
Kai Hwang
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Phase 3 Interventional Results available

Comparison of NN1250 With Insulin Glargine in Type 1 Diabetes

NCT01079234
View directory record Official record
Conditions
Diabetes, Diabetes Mellitus, Type 1
Interventions
insulin degludec, insulin glargine, insulin aspart
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
493 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
40
States / cities
Encino, California • Fresno, California • Huntington Beach, California + 34 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Cognition Study

NCT02773121
View directory record Official record
Conditions
Aging
Interventions
Physical Activity
Behavioral
Lead sponsor
Boston University
Other
Eligibility
55 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Jul 21, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes

NCT05540704
View directory record Official record
Conditions
Type 1 Diabetes, Eating Disorders, Disordered Eating Behaviors, Purging (Eating Disorders), Binge-Eating Disorder
Interventions
ACT, Supportive Diabetes Counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
16 Years to 50 Years
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Flexibility, Alcohol Misuse, and Excitation

NCT06634771
View directory record Official record
Conditions
Behavioral Flexibility, Healthy Volunteers, High Risk Alcohol Use
Interventions
10 Hz transcranial alternating current stimulation (tACS), sham transcranial alternating current stimulation (tACS)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
22 Years to 50 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Flexibility of Cognition And Persistent Pain

NCT02579538
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Cocoa and Metabolic Health in Prediabetes

NCT02203240
View directory record Official record
Conditions
Prediabetes
Interventions
Cocoa, Placebo
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validating a Novel Approach to Assess Metabolic Flexibility in a Respiratory Chamber

NCT05110274
View directory record Official record
Conditions
Metabolism
Interventions
Overnight Metabolic Flexibility, Clamp Metabolic Flexibility
Procedure
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Cognitive Flexibility Training in Persistent Pain

NCT03398408
View directory record Official record
Conditions
Chronic Pain
Interventions
Training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Jul 21, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility

NCT06785207
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
3D-printed scoliosis brace
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Houston, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Strive Cardio for Endometrial Cancer Survivors

NCT06534008
View directory record Official record
Conditions
Endometrial Cancer, Cardiovascular Diseases
Interventions
12-week home-based exercise intervention
Behavioral
Lead sponsor
Jess S. Gorzelitz
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Jul 21, 2026, 11:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate and 24-hour Effects of HyperVolt, Body Tempering, and Cupping Compared to Stretching on Hamstring Flexibility

NCT05793242
View directory record Official record
Conditions
Hamstring Contractures, Muscle Tightness
Interventions
Hypervolt, Body Tempering, Dry cupping, Static stretching
Device · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jul 21, 2026, 11:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Improvement of Body Image Flexibility in High School Female Athletes Doing Educational About Nutrition and Body Image

NCT05222360
View directory record Official record
Conditions
Body Image, Nutrition, Healthy
Interventions
Education
Other
Lead sponsor
Rocky Mountain Sports Medicine
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Parker, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Mindful Action for Pain

NCT03800654
View directory record Official record
Conditions
Chronic Pain
Interventions
Mindful Action for Pain, Cognitive Behavioral Therapy for Chronic Pain
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

rTMS-augmented Written Exposure Therapy for PTSD

NCT05149534
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Written Exposure Therapy, repetitive transcranial magnetic stimulation
Behavioral · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Studying Phenotypic Risks for Obesity and Underlying Traits in Young Infants

NCT07096011
View directory record Official record
Conditions
Infant Body Composition and Metabolism, Metabolism, Energy Expenditure, Infant Formula, Human Milk, Breast Milk, Metabolic Flexibility
Interventions
Meal Test - Human Milk, Meal Test - Infant Formula
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
2 Weeks to 16 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Prebiotics, Gut Microbiota, and Cardiometabolic Health

NCT02346838
View directory record Official record
Conditions
Prediabetes
Interventions
Inulin, Placebo
Dietary Supplement
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients

NCT03310099
View directory record Official record
Conditions
Heart Failure With Normal Ejection Fraction, Obesity
Interventions
Increasing daily unsaturated fatty acid consumption
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Exercise, Gut Microbiome, and Breast Cancer: Increasing Reach to Underserved Populations

NCT05000502
View directory record Official record
Conditions
Female Breast Cancer
Interventions
Home-based exercise intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility

NCT03630172
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kensington, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 11:20 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

TANDem-2: Closing the Gap to Interventions for TAND

NCT06879665
View directory record Official record
Conditions
Adult Caregivers of Individuals With TSC, Tuberous Sclerosis Complex (TSC)
Interventions
Well-Beans for Caregivers Program
Behavioral
Lead sponsor
Vrije Universiteit Brussel
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Energy Metabolism and Metabolic Flexibility in Older Men and Women

NCT03701867
View directory record Official record
Conditions
Energy Metabolism
Interventions
Metabolic Flexibility Tests
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
65 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa

NCT02883413
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
CRT + Teach the Parent, CRT + Contact Control
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Jul 21, 2026, 11:20 AM EDT