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Showing 25–42 of 42 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fluid Imbalance Clear all

Conditions: Wounds and Injuries, Multiple Trauma, Disorder of Fluid Balance
Interventions: Plasmalyte A, Normal Saline; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology), Renal Injury, Electrolyte and Fluid Balance Conditions
Interventions: PR Lotion - AMP Human Performance, Placebo Lotion, AminoVital - Rapid Recovery, Placebo Supplement; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Dehydration
Interventions: Water, Hydration Education; Other
Lead sponsor: PepsiCo Global R&D; Industry
Eligibility: 13 Years to 19 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Dehydration, Dehydration (Physiology), Glucose Abnormalities, Cardiovascular
Interventions: Baseline - week 1, Low Water Intake - week 2, Moderate Water Intake - week 3, Adequate Water Intake - week 4, Washout - week 5, Low fluid intake with non caloric sweeteners - Week 6, Moderate fluid intake with non caloric sweeteners - Week 7, Adequate fluid intake with non caloric sweeteners - Week 8; Other
Lead sponsor: Arizona State University; Other
Eligibility: 20 Years to 65 Years
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Phoenix, Arizona

Conditions: Dehydration
Interventions: Exercise Intervention; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Dehydration
Interventions: Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution; Drug
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Dehydration
Interventions: Distilled water, Medical Food 1, Medical Food 2, Pedialyte, Gatorade; Other
Lead sponsor: W. Larry Kenney; Other
Eligibility: 18 Years to 90 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
Interventions: tolvaptan, Fluid Restriction; Drug · Other
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 56
States / cities: Birmingham, Alabama • Mobile, Alabama • Azusa, California + 46 more

Conditions: Dehydration in Children, Dehydration
Interventions: LifeFlow; Device
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 1 Month to 18 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Ketosis
Interventions: D5 Lactated Ringer's Solution (D5LR), Lactated Ringer's Solution (LR); Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: Female only
Enrollment: 318 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Allentown, Pennsylvania • Bethlehem, Pennsylvania • Hershey, Pennsylvania + 1 more

Conditions: Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change, Heat Exposure, Hyperhydration, Electrolyte and Fluid Balance Conditions
Interventions: PR Lotion - AMP Human Performance, Placebo Lotion; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Dehydration
Interventions: 5% Dextrose (D5) in Normal Saline (NS), Normal Saline (NS); Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Months to 12 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hyponatremia
Interventions: Tolvaptan, Placebo, Hepatic Encephalopathy Assessment, Quality of Life Assessment, Vital signs, Blood laboratory tests, Ascites Evaluation, Edema; Drug · Behavioral · Biological + 1 more
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Hyponatremia With Normal Extracellular Fluid Volume, Hyponatremia With Excess Extracellular Fluid Volume
Interventions: Not listed
Lead sponsor: CardioKine Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 6
States / cities: Lomita, California • Clearewater, Florida • Fleming Island, Florida + 3 more

Conditions: Hyponatremia
Interventions: lixivaptan, Placebo; Drug
Lead sponsor: CardioKine Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 652 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 102
States / cities: Birmingham, Alabama • Mobile, Alabama • Bakersfield, California + 82 more

Conditions: Diabetic Ketoacidosis
Interventions: Two bag system; Other
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Dehydration (Physiology)
Interventions: Placebo, ConcenTrace, ZeroLyte; Dietary Supplement
Lead sponsor: Arizona State University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Electrolyte Imbalance, Hyponatremia, Hypernatremia
Interventions: V2R (Vasopressin 2 receptor); Drug
Lead sponsor: Oakland University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Rochester, Michigan

Search by objective public record fields.

Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients

The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress

Efficacy of Education Versus Education Plus Prescribed Fluid Intake on Hydration Status in High School Athletes

Adequate Hydration and Health Outcomes

Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)

Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A)

Effects of Amino Acid/Electrolyte-based Beverages on Hydration Status

Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia

LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound

A Trial of Intravenous Fluids During Labor

The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration

IV Glucose for Dehydration Treatment

Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia

International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430

THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation

Two Bag System for Diabetic Ketoacidosis

Rehydration With a Trace Mineral Supplement

V2 Receptor Effects on Fluid Regulation and Performance