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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:54 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 99 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fluid Management Clear all

Conditions: Liver Cancer
Interventions: Standard fluid management, Goal directed fluid therapy with the Edwards EV1000 system; Procedure · Device
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: End Stage Renal Failure
Interventions: Lower sodium intervention, Progressive Challenge to Post Dialysis Weight; Behavioral · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Livonia, Michigan

Conditions: Crohn's Disease, Ulcerative Colitis, Rectal Cancer, Colon Cancer, Colon Polyps, Rectal Polyps, Diverticulitis
Interventions: Hextend, Lactated Ringers; Drug
Lead sponsor: Corewell Health West; Other
Eligibility: 18 Years to 80 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Dehydration
Interventions: Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution; Drug
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Infant Acceptance of Medication
Interventions: Rx Medibottle; Device
Lead sponsor: Bronx-Lebanon Hospital Center Health Care System; Other
Eligibility: 2 Days to 24 Months
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Arthroplasty, Replacement, Knee
Interventions: Pre Operative Oral Fluids; Other
Lead sponsor: Colorado Joint Replacement; Other
Eligibility: 18 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Acute Decompensated Heart Failure
Interventions: Reprieve System, furosemide infusion; Device · Drug
Lead sponsor: Reprieve Cardiovascular, Inc; Industry
Eligibility: 22 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 35
States / cities: Irvine, California • Long Beach, California • Sacramento, California + 28 more

Conditions: Pleural Effusion
Interventions: Automatic Continuous Effusion Shunt implantation; Device
Lead sponsor: Pleural Dynamics, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: Hollywood, Florida • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more

Conditions: Cardiac Arrest, Pulseless Electrical Activity
Interventions: High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy; Drug
Lead sponsor: Carol Bernier; Other
Eligibility: 18 Years and older
Enrollment: 342 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Surgery
Interventions: Masimo Pulse CO-Oximeter; Device
Lead sponsor: Masimo Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Dehydration
Interventions: hylenex-facilitated subcutaneous Lactated Ringer's infusion; Drug
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: Lincoln, Nebraska • Neptune City, New Jersey

Conditions: Weight Gain
Interventions: Fluid intake app; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Healthy Subjects
Interventions: TI Inhalation Powder; Drug
Lead sponsor: Mannkind Corporation; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Heart Failure, High Blood Pressure, High Cholesterol, Anemia, Diabetes, Thyroid Diseases, Kidney Diseases, Clotting Disorder, Trauma, Other Disease
Interventions: BVA-200; Diagnostic Test
Lead sponsor: Daxor Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Oak Ridge, Tennessee

Conditions: Acute Kidney Injury, VExUS
Interventions: Fluid Management, No intervention; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Interventions: VExUS score; Diagnostic Test
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Decision Support System, Outcome
Interventions: Routine care, AFM; Procedure · Device
Lead sponsor: Assistance Publique - Hôpitaux de Paris; Other
Eligibility: 18 Years and older
Enrollment: 2,007 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Irvine, California • Los Angeles, California

Conditions: Prostate Cancer
Interventions: Enzalutamide Liquid, Enzalutamide Capsule; Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Neoplasms
Interventions: AVI-4126 Injection (RESTEN-NG®); Drug
Lead sponsor: Sarepta Therapeutics, Inc.; Industry
Eligibility: 18 Years to 64 Years · Male only
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Pain, Pain, Postoperative
Interventions: Acetaminophen 650 mg Oral Tablet, Acetaminophen 650mg Liquid, CADD pump; Drug · Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Device Related Sepsis
Interventions: Lifeflow, Push/Pull, Pressure Bag; Device
Lead sponsor: Yale University; Other
Eligibility: Not listed
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Pain, Acute
Interventions: VTS-K; Drug
Lead sponsor: Antonios Likourezos; Other
Eligibility: 18 Years to 110 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Intraoperative Volume Status, Postoperative Complications
Interventions: Closed Loop; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Orange, California

Conditions: Encephalitis
Interventions: AVI-4065 Injection; Drug
Lead sponsor: Sarepta Therapeutics, Inc.; Industry
Eligibility: 18 Years to 64 Years · Male only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Tacoma, Washington

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Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Liver Resection

Volume,Sodium and Blood Pressure Management in HD

An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy

Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A)

Administration of a Bitter-Tasting Medication: Comparison Between the Rx Medibottle and the Oral Syringe

Traditional vs Oral Fluid Management in Total Knee Arthroplasty

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

The ACES Study for Aseptic Pleural Effusion

Surviving PEA in Roanoke (SPEAR) Study

Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI

Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase

Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis , Full Scale Trial

A Trial to Determine How Long Insulin and FDKP (the Molecule That Forms Technosphere Particles) Stays in the Lungs of Healthy Individuals After Inhalation of Technosphere® Insulin (TI) Powder Using Bronchoalveolar Lavage (BAL)

BVA-200 vs BVA-100 Validation Study

Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness

De-resuscitation Informed by Ultrasound for Patients With Sepsis

Assisted Fluid Management (AFM) System and Postoperative Outcome After High-risk Abdominal Surgery

Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose Administration Under Fasting Conditions in Prostate Cancer

Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid

Patient Controlled Administration of Liquid Acetaminophen

Novel Device for Rapid Fluid Administration

Analgesic Efficacy of Orally Administered VTS-K for Pain Management

Closed-Loop Fluid Administration System Using Hemodynamic Monitors

Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid