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ClinicalTrials.gov public records Last synced Oct 15, 2026, 10:02 AM EDT

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Showing 697–720 of 756 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Foot Disease Clear all
Completed Phase 2 Interventional

Three-Arm Trial of Novel Treatment for Tinea Pedis

NCT03135912
View directory record Official record
Conditions
Tinea Pedis
Interventions
Experimental Drug SESC 01, Placebo, Terbinafine Hydrochloride
Drug
Lead sponsor
South End Skin Care
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Milford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 15, 2026, 10:02 AM EDT
Terminated Phase 2 Interventional Results available

Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer

NCT00751101
View directory record Official record
Conditions
Breast Cancer, Chemotherapeutic Agent Toxicity, Palmar-plantar Erythrodysesthesia
Interventions
Nicotine patch
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 15, 2026, 10:02 AM EDT
Completed No phase listed Observational Results available

MIRODERM H2H DFU Study

NCT03232333
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Biologic wound graft
Device
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Timeline
2017 – 2018
U.S. locations
9
States / cities
Carlsbad, California • Winter Haven, Florida • Avon, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Oct 15, 2026, 10:02 AM EDT
Active, not recruiting Not applicable Interventional

Wearable Insoles for Recurrent Diabetic Ulcer Prevention

NCT07674420
View directory record Official record
Conditions
Diabetes, Peripheral Neuropathy, Diabetic Foot Ulcer
Interventions
Orpyx Sensory Insole System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Not yet recruiting Phase 1 Interventional

Placental Cells for Diabetic Foot Ulcers

NCT07686094
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Placenta Stem Cells
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Stories to Educate Patients With Ankle, Foot, and Knee Injuries

NCT01810523
View directory record Official record
Conditions
Injury
Interventions
Narrative, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Phase 3 Interventional

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

NCT05773846
View directory record Official record
Conditions
Bunion
Interventions
Ropivacaine
Drug
Lead sponsor
PainReform LTD
Industry
Eligibility
18 Years and older
Enrollment
428 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
7
States / cities
Little Rock, Arkansas • Miami, Florida • Dayton, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 15, 2026, 10:02 AM EDT
Recruiting Not applicable Interventional

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

NCT06674980
View directory record Official record
Conditions
Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
Interventions
Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU, Standard of Care - VLU, AM/Single - VLU, AM/Double - VLU
Other
Lead sponsor
C5 Biomedical
Industry
Eligibility
18 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Metairie, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 15, 2026, 10:02 AM EDT
Not listed Not applicable Interventional

Efficacy of a Custom Temporary Foot Orthosis for Plantar Fasciitis Treatment

NCT01882894
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
Custom PFO, Faux orthosis
Device · Other
Lead sponsor
University of Puget Sound
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 21, 2013 · Synced Oct 15, 2026, 10:02 AM EDT
Terminated Phase 4 Interventional Results available

The Relationship of Hemoglobin A1c and Diabetic Wound Healing

NCT01350102
View directory record Official record
Conditions
Diabetes, Type 1, Diabetes, Type 2, Foot Ulcer, Diabetic
Interventions
Bacitracin, AmeriGel®, Vitamin C
Drug · Dietary Supplement
Lead sponsor
Susan Hassenbein
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Oct 15, 2026, 10:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma

NCT00284583
View directory record Official record
Conditions
Morton's Neuroma
Interventions
Injection of Steroid into Foot, Injection of Alcohol into Foot, Injection of Lidocaine into Foot
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 1, 2006 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Not applicable Interventional

CGM and DFU Healing Post-discharge

NCT06054659
View directory record Official record
Conditions
Diabetic Foot, Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown
Interventions
Real Time Continuous Glucose Monitoring (rt-CGM), Fingerstick blood glucose (FBG) monitoring, Diabetes Education
Device · Other · Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Recruiting Phase 4 Interventional

Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

NCT07326553
View directory record Official record
Conditions
Diabete Mellitus, Foot Ulcer Chronic
Interventions
Placental Membrane
Biological
Lead sponsor
BioXTek
Industry
Eligibility
45 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Completed No phase listed Observational

Inflammatory Biomarkers to Diagnose and Monitor Diabetic Foot Osteomyelitis

NCT04025853
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 15, 2026, 10:02 AM EDT
Terminated Not applicable Interventional Results available

Ketorolac Effects on Post-operative Pain and Bone Healing

NCT01133639
View directory record Official record
Conditions
Bunion
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Not applicable Interventional Results available

Cryotherapy for the Prevention of Taxane-Induced Sensory Neuropathy of the Hands and Feet in Breast Cancer Patients

NCT04256512
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Medical Device Usage and Evaluation, Questionnaire Administration
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 15, 2026, 10:02 AM EDT
Recruiting Not applicable Interventional

Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers

NCT07161830
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Omeza® Complete Matrix, Standard of Care
Device · Other
Lead sponsor
Omeza, LLC
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
10
States / cities
Evergreen Park, Illinois • Denham Springs, Louisiana • Leesville, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Phase 2 Interventional Results available

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

NCT06319287
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
PEP (Purified Exosome Product) / TISSEEL
Biological
Lead sponsor
Rion Inc.
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Not applicable Interventional Results available

A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.

NCT05145439
View directory record Official record
Conditions
Diabetic Foot Ulcer, Peripheral Arterial Disease, Wound; Foot
Interventions
VibratoSleeve Therapeutic Ultrasound Device
Device
Lead sponsor
Vibrato Medical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Not applicable Interventional Results available

Larval Debridement Therapy Versus Sharp Debridement to Remove Biofilm

NCT02294175
View directory record Official record
Conditions
Lower Extremity or Diabetic Foot Ulcers, Bacterial Infection
Interventions
Larval Debridement Therapy, Bedside Sharp Debridement
Device · Procedure
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Phase 1 Interventional

EZCast-DFU Study With Portal for Application of Topical Medications

NCT02131961
View directory record Official record
Conditions
Foot Ulcer, Diabetic Foot
Interventions
Collagenase ointment, Modified Contact Cast System
Drug · Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Oct 15, 2026, 10:02 AM EDT
Not listed Not applicable Interventional

Use of AC5® Advanced Wound System in the Treatment of Diabetic Foot Ulcers

NCT06028386
View directory record Official record
Conditions
Non-healing Wound, Diabetic Foot Ulcer
Interventions
AC5® Advanced Wound System, Fibracol Plus Collagen Dressing
Device
Lead sponsor
Arch Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Greenville, North Carolina • Circleville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 15, 2026, 10:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Mobility Interventions in the Real World

NCT04275973
View directory record Official record
Conditions
Lower Limb Amputation, Drop Foot
Interventions
Lower limb prostheses, Orthoses for Drop-foot
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 15, 2026, 10:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Evaluate Safety, of NextraTM in Surgery to Fuse the Proximal-interphalangeal- Joints

NCT01604070
View directory record Official record
Conditions
Foot Diseases
Interventions
Not listed
Lead sponsor
eMedtrain Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
4
States / cities
Cambridge, Massachusetts • Vineland, New Jersey • Alexandria, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Oct 15, 2026, 10:02 AM EDT