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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Foot Fusion Clear all
Completed Phase 1Phase 2 Interventional Results available

Study of Tumor Necrosis Factor Receptor Fusion Protein Etanercept (Enbrel) in Psoriasis of the Hands and/or Feet

NCT00585650
View directory record Official record
Conditions
Psoriasis
Interventions
Etanercept, Placebo injections
Biological · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
3
States / cities
Irvine, California • Winston-Salem, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Jul 22, 2026, 8:12 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Wright Foot & Ankle Post-Market Observational Study

NCT04118894
View directory record Official record
Conditions
Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury, Fusion of Joint
Interventions
Foot and Ankle Devices
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Hamilton, New Jersey • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jul 22, 2026, 8:12 AM EDT
Terminated Not applicable Interventional Results available

Pericapsular Exparel for Pain Relief in Bunionectomy and Related Procedures

NCT02499575
View directory record Official record
Conditions
Bunion, Hallux Rigidus
Interventions
0.5% ropivacaine, Exparel
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Jul 22, 2026, 8:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Weight Bearing Tarsometatarsal Fusion Study

NCT03812237
View directory record Official record
Conditions
Hallux Valgus
Interventions
(EWB) Early Weight Bearing (2 Weeks Post-op)
Other
Lead sponsor
Orthopaedic Associates of Michigan, PC
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Jul 22, 2026, 8:12 AM EDT
Completed Not applicable Interventional Results available

Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions

NCT00583375
View directory record Official record
Conditions
Foot Fusion
Interventions
Augment® Bone Graft, Standard of Care
Device · Procedure
Lead sponsor
BioMimetic Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
414 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
31
States / cities
Tucson, Arizona • San Francisco, California • Santa Cruz, California + 27 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Jul 22, 2026, 8:12 AM EDT
Completed No phase listed Observational

Evaluation of Trinity Evolution in Patients Undergoing Foot and Ankle Fusion

NCT00988338
View directory record Official record
Conditions
Tibiotalar Arthrodesis, Subtalar Arthrodesis, Calcaneocuboid Arthrodesis, Talonavicular Arthrodesis, Double Arthrodesis (i.e. Calcaneocuboid and Talonavicular), Triple Arthrodesis (i.e. Subtalar, Calcaneocuboid, and Talonavicular)
Interventions
Trinity Evolution
Biological
Lead sponsor
Orthofix Inc.
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
10
States / cities
Hollywood, Florida • Baltimore, Maryland • Albuquerque, New Mexico + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Jul 22, 2026, 8:12 AM EDT
Not listed No phase listed Observational

The Use of a Dynamic Sustained Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis

NCT04831645
View directory record Official record
Conditions
Ankle Arthritis, Arthritis Foot
Interventions
DynaNail, Tibiotalocalcaneal Arthrodesis
Device · Procedure
Lead sponsor
MedShape, Inc
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Worthington, Ohio
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Jul 22, 2026, 8:12 AM EDT
Completed Early Phase 1 Interventional

Does Supplementing Vitamin D Deficiency Affect Fusion Healing Rates in Elective Foot and Ankle Surgery?

NCT04450199
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D2, Placebo
Drug · Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Jul 22, 2026, 8:12 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

NCT04715139
View directory record Official record
Conditions
Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle, Lisfranc Arthrodesis, Mono or Bi-cortical Osteotomies in the Forefoot, First Metatarsophalangeal Arthrodesis, Akin Osteotomy, Midfoot and Hindfoot Arthrodeses or Osteotomies, Fixation of Osteotomies for Hallux Valgus Treatment (Scarf and Chevron), Arthrodesis of the Metatarsocuneiform Joint to Reposition and Stabilize Metatarsus Primus Varus, Osteotomy Fixation of Hallux Valgus Repair (Such as Scarf and Chevron Etc.), Medial Ankle Stabilization, Tibiotalocalcaneal Arthrodesis
Interventions
Products listed in Group/Cohort Description
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
2 Years and older
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
5
States / cities
Sacramento, California • Chicago, Illinois • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 22, 2026, 8:12 AM EDT
Active, not recruiting Early Phase 1 Interventional

Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery

NCT04772196
View directory record Official record
Conditions
Ankle Arthrodesis, MTP Arthrodesis
Interventions
Vitamin D3
Drug
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years to 99 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Charleston, South Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 8:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Investigating Auto Adjusting Dynamic AFO

NCT04623853
View directory record Official record
Conditions
Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
Interventions
Variable Stiffness AFO
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 8:12 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries

NCT04518462
View directory record Official record
Conditions
Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion, Midfoot Fusion, Hindfoot Fushion, Total Ankle Arthroplasty
Interventions
Exparel, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
5
States / cities
Phoenix, Arizona • Pasadena, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2022 · Synced Jul 22, 2026, 8:12 AM EDT
Not listed No phase listed Observational

Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft

NCT02879149
View directory record Official record
Conditions
Ankle and Hindfoot Arthrodesis
Interventions
AUGMENT® Bone Graft, Standard of Care
Device · Procedure
Lead sponsor
BioMimetic Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
21
States / cities
Tucson, Arizona • Capitola, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Jul 22, 2026, 8:12 AM EDT
Terminated Not applicable Interventional

TMT Fusion Plate vs. Two Crossed Screws

NCT02096146
View directory record Official record
Conditions
Clinical Indication for First Metatarsal Joint Arthrodesis
Interventions
TMT Fusion plate, Two crossed screws
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
East Lansing, Michigan • Woodbury, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Jul 22, 2026, 8:12 AM EDT
Not listed No phase listed Observational

Burst Biologics Foot and Ankle Registry

NCT03077256
View directory record Official record
Conditions
Foot and Ankle Disorders, Ankle Fusion, Osteotomy
Interventions
BioBurst Fluid, Burst Allograft
Device
Lead sponsor
Burst Biologics
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 27, 2019 · Synced Jul 22, 2026, 8:12 AM EDT
Enrolling by invitation Phase 4 Interventional

Periarticular Injection Versus Popliteal Block

NCT04575688
View directory record Official record
Conditions
Foot Surgery, Ankle Surgery
Interventions
Exparel, Bupivicaine
Drug
Lead sponsor
Campbell Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 22, 2026, 8:12 AM EDT