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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:19 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 396 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Foot Ulcers, Diabetic Clear all

Conditions: Venous Leg Ulcers, Diabetic Foot Ulcers
Interventions: PICO System, tNPWT System; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 15
States / cities: Carlsbad, California • Fresno, California • Martinez, California + 12 more

Conditions: Diabetic Foot Ulcer
Interventions: Alert for temperature delta; Device
Lead sponsor: DAPS Health LLC; Other
Eligibility: 35 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Annapolis, Maryland

Conditions: Chronic Diabetic Foot Ulcers
Interventions: CHAM, Control; Biological · Other
Lead sponsor: Osiris Therapeutics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 18
States / cities: Tucson, Arizona • Carlsbad, California • Castro Valley, California + 15 more

Conditions: Diabetic Foot Ulcers
Interventions: PRP Concepts Fibrin Bio-Matrix, Usual and Customary Practice; Device · Other
Lead sponsor: PRP Concepts, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Diabetic Foot Ulcers
Interventions: AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers; Other
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 8
States / cities: Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more

Conditions: Chronic Diabetic Foot Ulcers, Diabetic Neuropathic Ulcers, Non Healing Wound
Interventions: Timolol, Non biologically active gel; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer, Venous Ulcer
Interventions: Debritom; Device
Lead sponsor: Stephanie Wu; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: North Chicago, Illinois

Conditions: Non-healing Wounds
Interventions: Natrox Topical Oxygen Therapy; Device
Lead sponsor: Inotec AMD Limited; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Diabetic Foot Ulcer
Interventions: PEP (Purified Exosome Product) / TISSEEL; Biological
Lead sponsor: Rion Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Blue Ash, Ohio

Conditions: Diabetic Foot Ulcer
Interventions: 3C Patch; Device
Lead sponsor: Reapplix; Other
Eligibility: Not listed
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 6
States / cities: Phoenix, Arizona • Natchitoches, Louisiana • Opelousas, Louisiana + 3 more

Conditions: Diabetic Foot Ulcer
Interventions: Folinic acid calcium salt; Combination Product
Lead sponsor: Joseph Boykin, MD; Federal
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Wound Heal, Diabetic Foot Ulcer
Interventions: EDX110; Device
Lead sponsor: ConvaTec Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 9
States / cities: Phoenix, Arizona • Los Angeles, California • Santa Ana, California + 6 more

Conditions: Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions: Not listed
Lead sponsor: Dynamic Medical Services dba Acesso Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 2
States / cities: Novi, Michigan • Murfreesboro, Tennessee

Conditions: Diabetic Foot Ulcer
Interventions: HO/03/03 10µg, Placebo; Drug
Lead sponsor: HealOr; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 19
States / cities: Phoenix, Arizona • Castro Valley, California • Long Beach, California + 14 more

Conditions: Diabetic Foot Ulcer
Interventions: Dressing Application, Offloading; Procedure · Device
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Tulsa, Oklahoma • Roanoke, Virginia

Conditions: Diabetic Foot Ulcer (DFU)
Interventions: Xcell Amnio Matrix, Standard of Care (SOC); Biological · Drug
Lead sponsor: New Horizon Medical Solutions; Network
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 3
States / cities: Fresno, California • San Diego, California • Dallas, Texas

Conditions: Diabetic Foot Ulcer
Interventions: Tenex TXB MicroTip Ultrasound system plus SOC, Standard of Care for diabetic foot ulcer; Device · Other
Lead sponsor: Tenex Health Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Mobile, Alabama • St. George, Utah

Conditions: Diabetic Foot, Varicose Ulcer, Pressure Ulcer
Interventions: Versajet Hydrosurgery System, Conventional surgical debridement techniques; Device · Procedure
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 1
States / cities: Belleville, New Jersey

Conditions: Peripheral Arterial Disease, Peripheral Artery Disease, Peripheral Vascular Diseases, Diabetic Foot, Diabetic Foot Ulcer, Diabetic Foot Infection, Diabetic Peripheral Neuropathy
Interventions: Telemedicine specialty consultation; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Diabetic Foot Infection
Interventions: Topical pexiganan cream 0.8%, Topical placebo cream, Standard wound care; Drug · Other
Lead sponsor: Dipexium Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 39
States / cities: Phoenix, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 36 more

Conditions: Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
Interventions: ENERGI-F703 GEL, ENERGI-F703 matched vehicle; Drug
Lead sponsor: Energenesis Biomedical Co., Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 230 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 10
States / cities: Miami, Florida • Palmetto Bay, Florida • Columbus, Georgia + 4 more

Conditions: Diabetic Foot Ulcers, Diabetic Foot Wounds
Interventions: Santyl, Control; Biological · Procedure
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 7
States / cities: Phoenix, Arizona • Tucson, Arizona • Southfield, Michigan + 3 more

Conditions: Diabetic Foot Ulcer (DFU)
Interventions: OneStep Foot Scanner; Device
Lead sponsor: Bluedrop Medical Limited; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: North Port, Florida • Monroeville, Pennsylvania

Conditions: Diabetic Foot Ulcers
Interventions: ofloxacin, MSI-78; Drug
Lead sponsor: Abeona Therapeutics, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 584 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Seattle, Washington

Search by objective public record fields.

Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)

A Predictive Technology for Prevention of Diabetic Foot Ulcers

Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers

A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Non-Healing Diabetic Foot Ulcers

Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers

Beta Adrenergic Antagonist for the Healing of Chronic DFU

Debritom - Micro Water Jet Technology and Wound Healing

Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

3C Patch® Medicare Claims Study

Evaluation of a Folic Acid Wound Treatment (FAWT) for Chronic, Early-Stage Diabetic Foot Ulcer (DFU) Healing

EDX110 Randomized Control Trial for Treatment of DFUs

HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU

Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers

DHACM vs Other Commercially Available Treatments

A Prospective Clinical Study to Evaluate the Effectiveness and Safety of Xcell Amnio MatrixTM (XAM) in the Management of Chronic Non-healing DFUs

Prospective, Multicenter, RCT of the Tenex Ultrasound System

Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower Limb Ulcers

Implementation of Telemedicine for Patient With Lower Extremity Wounds

Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers

A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer

Using Santyl on Diabetic Foot Ulcers

Remote Temperature and Visual Monitoring To Help Manage Diabetic Foot Ulcers

MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers