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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:38 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 396 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Foot Ulcers, Diabetic Clear all

Conditions: Wound Heal, Ulcer
Interventions: InnovaMatrix® AC; Device
Lead sponsor: ConvaTec Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 21
States / cities: Fresno, California • Los Angeles, California • San Diego, California + 16 more

Conditions: Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Chronic Non Healing Wound, Surgical Wound Dehiscence
Interventions: Cellular and tissue based products; Biological
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 50,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Foot Ulcer, Diabetic
Interventions: NuShield, Affinity, Standard of Care; Other
Lead sponsor: NuTech Medical, Inc; Industry
Eligibility: 19 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 7
States / cities: Fresno, California • Indianapolis, Indiana • Opelousas, Louisiana + 4 more

Conditions: Diabetic Foot, Pedal Ulcers
Interventions: Optimal Medical Therapy Debridement + Toad Brace, Optimal Medical Therapy - Debridement; Device · Other
Lead sponsor: Toad Medical Corporation; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2013
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diabetic Foot Ulcers, Diabetic Foot Wounds
Interventions: Collagenase SANTYL® Ointment, Hydrogel (if needed) and foam dressing; Biological
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 22
States / cities: Mesa, Arizona • Carlsbad, California • Castro Valley, California + 19 more

Conditions: Diabetic Foot Ulcer
Interventions: Vaporous Hyperoxia Therapy; Device
Lead sponsor: Vaporox; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Castle Rock, Colorado • Denver, Colorado

Conditions: Neuropathic Diabetic Ulcer - Foot
Interventions: RedDress Wound Care System (RD1); Device
Lead sponsor: RedDress Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 4
States / cities: Miami, Florida • North Miami Beach, Florida • Pittsburgh, Pennsylvania + 1 more

Conditions: Diabetic Foot Ulcers (DFUs)
Interventions: E-GRAFT ™, FIBRACOL™; Other · Device
Lead sponsor: Skye Biologics Holdings, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Diabetes, Diabetic Foot Ulcer, Peripheral Neuropathy, Peripheral Arterial Disease
Interventions: Electrical Stimulation - Active, Electrical Stimulation - Sham; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 85 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Diabetic Foot Ulcers
Interventions: The Provant Therapy System; Device
Lead sponsor: Regenesis Biomedical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Diabetic Foot Ulcer, Surgical Wound
Interventions: Natrox® Oxygen Wound Therapy; Device
Lead sponsor: Inotec AMD Limited; Industry
Eligibility: 18 Years and older
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 19
States / cities: Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more

Conditions: Neuropathic Diabetic Foot Ulcers
Interventions: Placebo, UTTR1147A; Drug
Lead sponsor: Genentech, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 10
States / cities: Mesa, Arizona • San Francisco, California • Durango, Colorado + 7 more

Conditions: Diabetic Foot Ulcer
Interventions: Weekly application of EpiFix plus standard of care, Biweekly application of EpiFix plus standard of care; Other
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Roanoke, Virginia • Salem, Virginia

Conditions: Diabetic Foot, Ulcer Foot
Interventions: Human split thickness skin allograft, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing; Other
Lead sponsor: Professional Education and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 5
States / cities: San Francisco, California • O'Fallon, Illinois • Youngstown, Ohio + 2 more

Conditions: Diabetic Foot Ulcer
Interventions: ProgenaMatrix Keratin graft, standard of care; Device · Other
Lead sponsor: ProgenaCare Global, LLC; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Puyallup, Washington

Conditions: Diabetic Foot Ulcer
Interventions: OptiPulse™, Standard of Care offloading device; Device
Lead sponsor: Compedica Inc; Industry
Eligibility: 18 Years and older
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 18
States / cities: Phoenix, Arizona • Los Angeles, California • Vista, California + 12 more

Conditions: Critical Limb Ischemia
Interventions: Oxygenesys(TM) Dissolved Oxygen Dressing; Device
Lead sponsor: Halyard Health; Industry
Eligibility: 21 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Diabetic Foot Infection
Interventions: Topical pexiganan cream 0.8%, Topical placebo cream, Standard wound care; Drug · Other
Lead sponsor: Dipexium Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 30
States / cities: Birmingham, Alabama • Glendale, Arizona • Mesa, Arizona + 27 more

Conditions: Diabetic Foot Ulcers
Interventions: DermaPure™, Standard care; Other
Lead sponsor: TRx Wound Care Limited; Industry
Eligibility: 19 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 7
States / cities: Phoenix, Arizona • Miami, Florida • New York, New York + 3 more

Conditions: Diabetic Foot Ulcers
Interventions: AutoloGel; Device
Lead sponsor: Cytomedix; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Arcadia, California • Cumming, Georgia

Conditions: Diabetic Foot
Interventions: GAM501, Placebo, Standard of care; Biological · Other
Lead sponsor: Tissue Repair Company; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 29
States / cities: Montgomery, Alabama • Mesa, Arizona • Phoenix, Arizona + 24 more

Conditions: Diabetic Foot Ulcers (DFUs)
Interventions: Antimicrobial agent; Drug
Lead sponsor: Lakewood-Amedex Inc; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 6
States / cities: Los Angeles, California • Doral, Florida • Margate, Florida + 3 more

Conditions: Diabetic Foot, Quality of Life, Mental Health Wellness 1, Ulcer Foot, Diabetes Complications
Interventions: No intervention, this is an observational study; Other
Lead sponsor: Podimetrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Diabetic Foot, Leg Ulcer, Decubitus Ulcer
Interventions: Not listed
Lead sponsor: Southwest Regional Wound Care Center; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2018
U.S. locations: 1
States / cities: Lubbock, Texas

Search by objective public record fields.

IDEAL: Efficacy of Porcine Placental Extracellular Matrix Augmented Plus Standard of Care (SOC) Versus SOC Alone for the Management of Diabetic Foot Ulcers

Cellular and Tissue Based Therapy Registry

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

Randomized, Prospective Evaluation of the Toad Brace in Plantar Ulcer Off-loading and Healing

Santyl Applications to Diabetic Foot Ulcers

Effectiveness of Vaporous Hyperoxia Therapy (VHT) in the Treatment of Chronic Diabetic Foot Ulcers

Safety Trial of the RedDress Wound Care System (RD1) in Management of Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.

Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care

Electrical Stimulation to Accelerate Wound Healing

A Pilot Study of the Provant Therapy System in Subjects With Diabetic Foot Ulcers

The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UTTR1147A in Participants With Neuropathic Non-Healing Diabetic Foot Ulcers

Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers

Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers

Efficacy of ProgenaMatrix™ in the Management of DFUs

A Clinical Investigation Evaluating Wound Closure With OptiPulse™ Versus SOC in the Treatment of Non-Healing DFU's

Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia

Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers

A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers

Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers

Phase 2b Study of GAM501 in the Treatment of Diabetic Ulcers of the Lower Extremities

Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFU

Patient Empowerment Study

Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study