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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Footdrop Clear all
Terminated Not applicable Interventional Results available

The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop

NCT01001390
View directory record Official record
Conditions
Foot Drop, Acute Lymphoblastic Leukemia
Interventions
AFO Device
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
6 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Mobility Interventions in the Real World

NCT04275973
View directory record Official record
Conditions
Lower Limb Amputation, Drop Foot
Interventions
Lower limb prostheses, Orthoses for Drop-foot
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.

NCT02693834
View directory record Official record
Conditions
Stroke, CVA, Hemiplegia, Hemiparesis, Foot Drop
Interventions
Posterior Leaf spring AFO, Double adjustable AFO
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors

NCT01029912
View directory record Official record
Conditions
Stroke, Hemiparesis, Lower Extremity Paresis
Interventions
Electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Jul 22, 2026, 9:02 AM EDT
Terminated Phase 1Phase 2 Interventional

Targeted Lower Extremity Joint Training

NCT00765544
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Anklebot, Lokomat
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 22, 2013 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke

NCT02199795
View directory record Official record
Conditions
Stroke, Hemiparesis, Footdrop
Interventions
Contralaterally Controlled Neuromuscular Electrical Stimulation, Cyclic Neuromuscular Electrical Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Jul 22, 2026, 9:02 AM EDT
Withdrawn Not applicable Interventional

TREAT Foot Drop After Stroke With Ankle Robot

NCT04137809
View directory record Official record
Conditions
Foot Drop, Stroke, Hemiparesis
Interventions
AMBLE
Device
Lead sponsor
NextStep Robotics Inc.
Industry
Eligibility
21 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Jul 22, 2026, 9:02 AM EDT
Withdrawn Not applicable Interventional

Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee Arthroplasty

NCT02856958
View directory record Official record
Conditions
Peroneal Palsy (Foot Drop)
Interventions
Nerve decompression, Non-operative
Procedure · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Functional Electrical Stimulation for Footdrop in Hemiparesis

NCT00148343
View directory record Official record
Conditions
Stroke, Hemiplegia
Interventions
Odstock Dropped-Foot Stimulator (ODFS), Conventional Standard of Care, Traditional Physical Therapy Treatment
Device · Other · Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care

NCT06919289
View directory record Official record
Conditions
Drop Foot
Interventions
Infiltration of papaverine, Lidocaine infiltration
Drug
Lead sponsor
US Neuropathy Centers
Other
Eligibility
Not listed
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jasper, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Ankle Robot to Reduce Foot Drop in Stroke

NCT02483676
View directory record Official record
Conditions
Stroke, Foot Drop
Interventions
Treadmill plus anklebot, Treadmill only
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Jul 22, 2026, 9:02 AM EDT
Terminated Not applicable Interventional

Neuromodulation of Ankle Muscles in Persons With SCI

NCT04238013
View directory record Official record
Conditions
Spinal Cord Injuries, Spastic Gait, Foot Drop
Interventions
Whole Body Vibration (WBV), Electrical Stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities

NCT00906737
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Ankle-bot, Conventional focused ankle therapy
Device · Other
Lead sponsor
Mount Sinai Rehabilitation Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Effect of FES Interventions on Gait Dynamics in Stroke Population

NCT01952613
View directory record Official record
Conditions
Stroke, Foot Drop
Interventions
FES
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Jul 22, 2026, 9:02 AM EDT
Enrolling by invitation Not applicable Interventional

Can the Phoenix Sign be Elicited With D5W

NCT07568470
View directory record Official record
Conditions
Drop Foot
Interventions
Infiltration of D5W
Drug
Lead sponsor
US Neuropathy Centers
Other
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Augmenting Gait in a Population Exhibiting Foot Drop With Adaptive Functional Electrical Stimulation

NCT05346640
View directory record Official record
Conditions
Foot Drop
Interventions
Cionic Neural Sleeve
Device
Lead sponsor
Cionic, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
San Francisco, California • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jul 22, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

Ankle Robotics After Stroke

NCT04594837
View directory record Official record
Conditions
Foot Drop, Stroke, Hemiparesis
Interventions
PTR Physical Therapy while wearing Robot group (Phase II), Physical Therapy Only (Phase II), Cross over group for Physical Therapy n Sub-Acute group. (Phase II), Chronic Stroke Subjects to receive robotic gait training therapy.
Device · Other
Lead sponsor
NextStep Robotics Inc.
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Impact of an Orthotic Intervention in Children With Peripheral Neuropathy

NCT03655587
View directory record Official record
Conditions
Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma, Wilms Tumor
Interventions
Solid ankle foot orthotic, Resting night splint
Device
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
5 Years to 14 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 22, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop

NCT07592221
View directory record Official record
Conditions
Falls, Foot Drop, Post Stroke Recovery
Interventions
Standard protocol for combo of FES and tDCS
Behavioral
Lead sponsor
Saint Joseph's University, Philadelphia
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 22, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

Characterization and Clinical Trial of a Variable Friction Shoe

NCT06234124
View directory record Official record
Conditions
Stroke
Interventions
Variable Friction Shoe Training, Ankle Foot Orthosis (AFO) Training
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop

NCT01138995
View directory record Official record
Conditions
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis, Post-Cerebrovascular Accident (CVA) Hemiparesis
Interventions
Ness L300, Ankle-foot orthosis
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Downey, California • Long Beach, California • San Diego, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Jul 22, 2026, 9:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke

NCT05801744
View directory record Official record
Conditions
Stroke, Post-stroke Hemiparesis, Foot Drop
Interventions
Operant conditioning
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Phase 1Phase 2 Interventional

Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis

NCT00872053
View directory record Official record
Conditions
MS (Multiple Sclerosis)
Interventions
Anklebot, Lokomat
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Jul 22, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator

NCT06637046
View directory record Official record
Conditions
Drop Foot
Interventions
Diagnostic procedures, Lidocaine HCl
Diagnostic Test
Lead sponsor
Stephen Barrett
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Jul 22, 2026, 9:02 AM EDT