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ClinicalTrials.gov public records Last synced Nov 14, 2026, 3:27 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 188 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fractional Clear all

Conditions: Vestibulodynia
Interventions: Fractional CO2 Laser Treatment, Sham Laser Treatment; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Dyspareunia
Interventions: 4% Topical Lidocaine Gel, CO2RE fractional laser therapy; Drug · Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Skin Laxity
Interventions: Hybrid Fractional Laser; Device
Lead sponsor: Sciton; Industry
Eligibility: 40 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Montclair, New Jersey

Conditions: Improvement of Wrinkles/Elastosis as Well as General Skin Tone
Interventions: M22 ResurFX, M22 ResurFX and QS; Device
Lead sponsor: Lumenis Be Ltd.; Industry
Eligibility: 30 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Stretch Marks
Interventions: Combination treatment, 1550-nm erbium-doped fractionated laser; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Coronary Artery Disease
Interventions: RXi System, Pressure Wire; Device
Lead sponsor: Acist Medical Systems; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 12
States / cities: La Jolla, California • Long Beach, California • Stanford, California + 8 more

Conditions: Pain
Interventions: LMX4, BLT; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Burn Scar, Skin Graft Scar
Interventions: Lidocaine Cream, Triamcinolone Acetonide Cream, Fractional Ablative Laser; Drug · Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: Venus Viva MD; Device
Lead sponsor: Venus Concept; Industry
Eligibility: 22 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Ischemia
Interventions: CT and stress test; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 5
States / cities: Overland Park, Kansas • New York, New York • Columbus, Ohio + 2 more

Conditions: Angina
Interventions: Ranolazine, Sugar pill; Drug
Lead sponsor: North Florida Foundation for Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Skin Laxity
Interventions: Fractional ablative laser; Device
Lead sponsor: Sciton; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Rhytides, Wrinkle
Interventions: Venus Viva; Device
Lead sponsor: Venus Concept; Industry
Eligibility: 22 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Coronary Artery Disease
Interventions: Not listed
Lead sponsor: Volcano Corporation; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Male Pattern Hair Loss, Androgenetic Alopecia, Male Pattern Baldness
Interventions: Post-Laser Minoxidil 2%, At-Home Minoxidil 5%, Laser, Post-laser 5mg minoxidil, Post-laser 10mg minoxidil, Post-laser 20mg minoxidil; Drug · Device
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 65 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Stress Urinary Incontinence, Urinary Incontinence
Interventions: Active fCO2 laser treatment, Sham fCO2 laser treatment; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 75 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Coronary Artery Disease
Interventions: Invasive Cardiac Catheterization (ICA), Coronary Computed Tomographic Angiogram (CCTA), Dynamic Cardiac Positron Emission Tomography (dPET); Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 3
States / cities: Atlanta, Georgia • Roslyn, New York

Conditions: Acne Scars
Interventions: Fraxel Restore, Fractora; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Asthma
Interventions: NIOX MINO® Instrument (09-1100); Device
Lead sponsor: Aerocrine AB; Industry
Eligibility: 7 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 8
States / cities: Blue Bell, Pennsylvania • Collegeville, Pennsylvania • Doylestown, Pennsylvania + 5 more

Conditions: Surgical Incision
Interventions: Fractional Radiofrequency; Device
Lead sponsor: Venus Concept; Industry
Eligibility: 21 Years to 75 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cicatrix
Interventions: Fractional Radiofrequency, 1550-nm Fractional Photothermolysis; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Fractional Calcium Absorption
Interventions: Not listed
Lead sponsor: Cornell University; Other
Eligibility: 53 Years to 65 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: Coronary Artery Stenosis
Interventions: FFR, IVUS, VH, or combination of the three; Procedure
Lead sponsor: Piedmont Healthcare; Other
Eligibility: 21 Years to 85 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Wound Healing
Interventions: Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser; Other · Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

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Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors

Hybrid Fractional Laser for Treatment of Off Face Body Skin Quality

Impact of Synergistic Sequential Treatment (SST)

Fractional Laser and Ultrasound for Striae Distensae

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

Comparison Study on Topical Anesthetic Agents (LMX4 and BLT) Prior to Fractional Skin Resurfacing

Fractional Ablative Laser Treatment for Skin Grafts

Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring

Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques

Ranolazine Among Unrevascularized Chronic Stable Angina Patients

Evaluation of Fractional Ablative Laser Treatment for Skin Conditions

Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles

Fractional Flow Reserve and Intravascular Ultrasound RelationShip STudy

Laser Assisted Delivery of Minoxidil in Androgenetic Alopecia

A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women

Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery

Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin

A Study to Explore the Utility of Fractional Exhaled Nitric Oxide (FeNO) Compared With Methacholine Challenge (MCC) Testing in the Assessment of Patients With Suspected But Undiagnosed Asthma

Fractional Radiofrequency for Reduction of Surgical Scar Formation

A Pilot Study Testing Fractional Radiofrequency Versus Fractional Photothermolysis for the Treatment of Acne Scars

Calcium Absorption in Postmenopausal Thai Women

Validation of Stenosis Assessment by Coronary Artery Computed Tomography Against Invasive Measurements of Fractional Flow Reserve in Patients With Significant Coronary Artery Stenoses

Compression and CO2 Laser for Leg Wounds