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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fracture Humerus Clear all
Active, not recruiting No phase listed Observational

Affixus Natural Nail System Humeral Nail PMCF

NCT05019664
View directory record Official record
Conditions
Humeral Fractures, Proximal, Humeral Fractures
Interventions
humeral fracture
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Results available

Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

NCT03261830
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Post Operative Wound Infection
Interventions
Cefazolin, Clindamycin, Saline
Drug
Lead sponsor
Sumit Gupta
Other
Eligibility
Up to 13 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Results available

Exparel for Postoperative Pain Management in Shoulder Surgery

NCT02472314
View directory record Official record
Conditions
Fracture of Shoulder and Upper Arm
Interventions
1.3% Liposomal Bupivacaine, 0.125% Bupivacaine
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 4 Interventional Results available

Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management

NCT06187584
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
5 Years to 9 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Phase 4 Interventional

Supracondylar Post-Operative Pain Study

NCT03759028
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Ibuprofen, Oxycodone, Acetaminophen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Comparison of Bracing With Co-aptation Splinting for the Initial Treatment of Acute Humeral Shaft Fractures: The COBRAS Trials

NCT05118087
View directory record Official record
Conditions
Humeral Fractures
Interventions
Webril Padded Plaster Splint, Pre-Fabricated Fracture Brace
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Garden City, New York • New York, New York • Queens, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Proximal Humerus Fractures: A Retrospective Analysis

NCT03637608
View directory record Official record
Conditions
Proximal Humeral Fracture
Interventions
Not listed
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Jul 21, 2026, 10:21 PM EDT
Withdrawn Phase 2 Interventional

Efficacy of Tranexamic Acid (TXA) in Humerus ORIF

NCT05802238
View directory record Official record
Conditions
Fracture Humerus
Interventions
Tranexamic acid (TXA), Saline
Drug · Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture

NCT06869343
View directory record Official record
Conditions
Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
Interventions
Physical Therapy
Other
Lead sponsor
University of Virginia
Other
Eligibility
50 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed No phase listed Observational Results available

A Clinical Investigation of the Discovery™ Elbow System

NCT00698867
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis, Humeral Fractures
Interventions
Not listed
Lead sponsor
Biomet Orthopedics, LLC
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
4
States / cities
Tampa, Florida • Indianapolis, Indiana • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Phase 4 Interventional Results available

NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures

NCT04905563
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Acetaminophen-Hydrocodone, Acetaminophen and Ibuprofen
Drug
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
4 Years to 13 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Enrolling by invitation Not applicable Interventional

Anxiety Surrounding Supracondylar Pin Removal in Children: A Randomized Controlled Trial

NCT05501834
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Anxiety
Interventions
Supracondylar Pin Removal After Imaging With VR, Supracondylar Pin Removal Before Imaging, Supracondylar Pin Removal Before Imaging With VR
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 10 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting No phase listed Observational

Duration of Immobilization After Reverse Total Arthroplasty for Proximal Humerus Fractures

NCT06133920
View directory record Official record
Conditions
Proximal Humeral Fracture, Reverse Total Shoulder Arthroplasty
Interventions
Early Range of Motion, Immobilization
Other
Lead sponsor
The Cooper Health System
Other
Eligibility
60 Years and older
Enrollment
40 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty

NCT03617107
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
Interventions
reverse total shoulder arthroplasty
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Not applicable Interventional

Humeral Compression/Distraction Device

NCT02861495
View directory record Official record
Conditions
Humeral Fractures
Interventions
Humeral Compression/Distraction (CD) Nail
Device
Lead sponsor
Florida Orthopaedic Institute
Network
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Not applicable Interventional

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

NCT02597972
View directory record Official record
Conditions
Closed Fracture Proximal Humerus, Four Part
Interventions
Fracture repair, Fracture repair with joint replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Not applicable Interventional Results available

Progressive Splinting Status Post Elbow Fractures and Dislocations

NCT00580866
View directory record Official record
Conditions
Upper Extremity Fracture, Upper Extremity Dislocation, Fractures, Comminuted, Elbow Fracture, Elbow Dislocation
Interventions
JAS Brace
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 6, 2016 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 2 Interventional

A Study of rhBMP-2/CPM in Closed Fractures of the Humerus

NCT00384852
View directory record Official record
Conditions
Fractures
Interventions
rhBMP-2/CPM
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
9
States / cities
Little Rock, Arkansas • Aurora, Colorado • Denver, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2013 · Synced Jul 21, 2026, 10:21 PM EDT
Completed No phase listed Observational

Operative Versus Nonoperative Treatment of Humeral Shaft Fractures: A Prospective Cohort Comparison Study

NCT01363518
View directory record Official record
Conditions
Closed Fracture of Shaft of Humerus
Interventions
Not listed
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 65 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
7
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Burlington, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting No phase listed Observational

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

NCT01480440
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3-and 4-part Proximal Humeral Fractures, Avascular Necrosis, Gross Rotator Cuff Deficiency, Revision Total Shoulder Arthroplasty
Interventions
Trabecular Metal Reverse Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • Egg Harbor, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Acute Management of Humeral Shaft Fractures: Sling vs. Splint

NCT01869322
View directory record Official record
Conditions
Fracture of Shaft of Humerus
Interventions
Sling and Swathe, Coaptation Splint
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

NCT03626038
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Psoriatic Arthritis, Proximal Humeral Fracture
Interventions
A.L.P.S. Proximal Humerus Plating System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Effect of Occupational Therapy on the Function and Mobility of Elbow Fractures

NCT00871793
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Occupational therapy
Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
5 Years to 12 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 1, 2012 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Phase 4 Interventional Results available

Post-operative Pain Management in Children With Supracondylar Humerus Fractures

NCT05640674
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 21, 2026, 10:21 PM EDT