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Showing 1–24 of 236 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Distal Femur Fracture
Interventions
Distal femur plates
Device
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
3
States / cities
Sacramento, California • Houston, Texas • Fairfax, Virginia
Completed Phase 3 Interventional Results available

Effect of Teriparatide on Hip Fracture Healing

NCT01473589
Conditions
Femur Neck Fracture
Interventions
Teriparatide, Placebo, Calcium supplementation, Vitamin D supplementation
Drug · Dietary Supplement
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
50 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
24
States / cities
Phoenix, Arizona • Tucson, Arizona • La Mesa, California + 21 more
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Muscle Function After Ankle Surgery

NCT00060970
Conditions
Muscle Atrophy, Muscle Weakness, Fractures
Interventions
Physical Therapy
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2000
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Tibial Plateau Fractures
Interventions
Bupivacain
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Tibial Fractures, Pain
Interventions
600 mg Ibuprofen
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
13
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Cambridge, Massachusetts + 9 more
Completed No phase listed Observational Accepts healthy volunteers

Insole Sensor to Determine Optimal Limb Loading

NCT02170493
Conditions
Lower Extremity Fractures
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Femur Fracture
Interventions
Spica casting
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Years to 6 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Intramedullary Nailing of Tibia Fractures

NCT01797640
Conditions
Tibial Fractures, Malleolar Fractures
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 95 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture, Pelvic Fracture
Interventions
DuraPrep, ChloraPrep
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
8,485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
24
States / cities
Irvine, California • Los Angeles, California • San Jose, California + 20 more
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Conditions
Muscle Wasting (Atrophy) After Hip Fracture Surgery
Interventions
bimagrumab, placebo
Drug · Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
60 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Phoenix, Arizona • El Cajon, California • Denver, Colorado + 3 more
Conditions
Unstable Pelvic Ring Fracture, Unstable Acetabulum Fracture, Femur Fracture
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
16 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Terminated Not applicable Interventional Results available

Light Therapy in the Treatment of Leg Pain

NCT00253981
Conditions
Tibial Fractures, Leg Injuries
Interventions
Monochromatic Near-Infrared Light Energy (MIRE)
Device
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
El Paso, Texas
Conditions
Pain, Postoperative, Ankle Fractures
Interventions
Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Osteoporosis, Lower Limb Fracture
Interventions
OPTIONS, Enhanced usual care
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
1,344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland • Boston, Massachusetts
Recruiting Not applicable Interventional

Geriatric Distal Femur

NCT07237191
Conditions
Articular Fractures
Interventions
Single Implant Fixation, Dual Implant Fixation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlotte, North Carolina
Terminated Not applicable Interventional Results available

VeraFlo With Prontosan® and Wound and Fracture Healing.

NCT02621073
Conditions
Infection
Interventions
VeraFlo with Prontosan, V.A.C Ulta System
Drug · Device
Lead sponsor
Brett Crist
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Hip Fracture
Interventions
Femoral Nerve Catheterization, Intravenous Opioids
Procedure
Lead sponsor
Leslie Thomas
Other
Eligibility
50 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Active, not recruiting No phase listed Observational

Fragility Fractures of the Pelvis (FFP)

NCT04182776
Conditions
Pelvic Fracture
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
65 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Medial Malleolus Fractures
Interventions
Fixation by Acutrak headless screw, Fixation by headed screws, plates, and or wires
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
Palo Alto, California • Sacramento, California • Boston, Massachusetts
Conditions
Hip Fractures, Femoral Shaft Fractures
Interventions
Standard of Care, Distal targeting device technique of distal screw placement
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Hip Fracture, Disability
Interventions
Enhanced Strong for Life, cardiovascular nutrition education
Behavioral
Lead sponsor
Boston University
Other
Eligibility
60 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
Interventions
Manual Therapy Group, Control Group
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Ankle Fracture, Pilon Fracture
Interventions
ankle or distal tibia surgery
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
3
States / cities
Jacksonville, Florida • New York, New York