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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:10 AM EDT

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Showing 361–384 of 1,012 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Fractures, Bone Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Function Focused Care: Fracture Care at Home

NCT03147222
View directory record Official record
Conditions
Fractures, Bone, Dementia
Interventions
Fracture Care at Home
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 22, 2026, 4:10 AM EDT
Not listed Not applicable Interventional

Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study

NCT02032966
View directory record Official record
Conditions
Ankle Fracture, Malleolus Fracture, Medial Malleolus Fracture, Bimalleolar Fracture, Trimalleolar Fracture
Interventions
Nonsurgical, Surgical
Procedure
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 22, 2026, 4:10 AM EDT
Terminated Not applicable Interventional Results available

Novel Use of an Enhanced Fluoroscopic Imaging Device to Reduce Radiation Exposure and Operative Time During Intramedullary Nailing of Hip Fractures

NCT02856828
View directory record Official record
Conditions
Radiation Exposure
Interventions
DIE
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 22, 2026, 4:10 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

NCT05883241
View directory record Official record
Conditions
Bone Fracture, Fresh Fracture
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Trumbull, Connecticut • Lansdowne, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional Results available

A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures

NCT00718302
View directory record Official record
Conditions
Ankle Injuries
Interventions
Antiglide Plate, Lateral Plate
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
9
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Grand Rapids, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 22, 2026, 4:10 AM EDT
Terminated Not applicable Interventional

Prevention of Infection in Closed Fractures: Cefazolin Versus Vancomycin

NCT02027532
View directory record Official record
Conditions
Infection, Closed Fractures
Interventions
Cefazolin, Vancomycin
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 85 Years
Enrollment
430 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 22, 2026, 4:10 AM EDT
Completed No phase listed Observational

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage

NCT01496014
View directory record Official record
Conditions
Open Fracture
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 64 Years
Enrollment
646 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
40
States / cities
San Diego, California • San Francisco, California • Denver, Colorado + 34 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Phase 3 Interventional

Tobramycin Injection to Prevent Infection in Open Fractures

NCT04964947
View directory record Official record
Conditions
Wound Infection, Fractures, Open, Surgical Site Infection
Interventions
Tobramycin Injection
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Lexington, Kentucky • Boston, Massachusetts • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 22, 2026, 4:10 AM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 22, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Investigating Periprosthetic Fracture Cultures in Arthroplasty

NCT06952738
View directory record Official record
Conditions
Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions
Not applicable- observational study
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 22, 2026, 4:10 AM EDT
Completed No phase listed Observational

Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy

NCT02155595
View directory record Official record
Conditions
Osteoporosis, Atypical Femoral Fractures, Prodromal Bone Deterioration
Interventions
500 without BP treatment, 500 with BP treatment
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
50 Years and older · Female only
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2019 · Synced Oct 22, 2026, 4:10 AM EDT
Terminated No phase listed Observational

Effectiveness of Automated Inpatient Endocrinology Consultation for Osteoporotic Hip Fracture

NCT00643175
View directory record Official record
Conditions
Osteoporosis
Interventions
Automated follow up
Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2009 · Synced Oct 22, 2026, 4:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Trial of Ultrasound Guidance for Reduction of Pediatric Forearm Fractures

NCT03097757
View directory record Official record
Conditions
Forearm Fracture, Ultrasound
Interventions
Ultrasound - guided fracture reduction, Standard of care fracture reduction
Radiation · Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
Up to 21 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Oct 22, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Gait and Bone Health in SMA

NCT07400198
View directory record Official record
Conditions
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Interventions
Not listed
Lead sponsor
Jacqueline Montes
Other
Eligibility
8 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional

Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

NCT04028414
View directory record Official record
Conditions
Rehabilitation
Interventions
Early Weight Bearing
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years and older
Enrollment
435 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
17
States / cities
Birmingham, Alabama • San Francisco, California • Indianapolis, Indiana + 14 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Phase 2 Interventional Results available

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

NCT00848393
View directory record Official record
Conditions
Tetralogy of Fallot (TOF), Ventricular Septal Defects (VSD), Atrioventricular Septal Defects (AVSD)
Interventions
Fentanyl (High Dose), Fentanyl (Low Dose), Fentanyl (Low Dose) + Dexmedetomidine
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
1 Month to 3 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2018 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional

Pericapsular Nerve Group Block for Hip Fractures

NCT04882384
View directory record Official record
Conditions
Hip Fractures, Pain, Acute
Interventions
Pericapsular Nerve Group Block
Procedure
Lead sponsor
Jacobi Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 22, 2026, 4:10 AM EDT
Recruiting Not applicable Interventional

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

NCT05792189
View directory record Official record
Conditions
Distal Femur Fracture
Interventions
Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture, Koos Jr assesment on subjects with DFR of distal femur fracture
Other
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Does Omeprazole Decrease Intestinal Calcium Absorption?

NCT00582972
View directory record Official record
Conditions
Osteoporosis, Achlorhydria, GERD, Hip Fracture
Interventions
Omeprazole
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional Results available

Comparison of Operating Room Time Length With the Use of Virtual Surgical Planning Versus Conventional Treatment of Mandible Fractures

NCT04283981
View directory record Official record
Conditions
Mandibular Fractures
Interventions
Control group without use of VSP, Treatment Group with use of VSP
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Phase 4 Interventional

Accuracy of Navigation in Placement of Sacroiliac Screw

NCT00955565
View directory record Official record
Conditions
Hip Fracture
Interventions
Navigated, Conventional
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2010 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional Results available

Zoledronic Acid for Osteoporosis in the Elderly

NCT00558012
View directory record Official record
Conditions
Osteoporosis, Bone Loss, Fragility Fractures
Interventions
Intravenous zoledronic acid, Vitamin D 800 IU/daily, Calcium 1200 mg/daily
Drug · Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 31, 2015 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Phase 3 Interventional

Osteoporosis Prevention After Heart Transplant

NCT00000412
View directory record Official record
Conditions
Osteoporosis, Cardiac Transplantation
Interventions
Alendronate, Calcitriol, Placebo Alendronate, Placebo Calcitriol
Drug
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 70 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2015 · Synced Oct 22, 2026, 4:10 AM EDT
Completed Not applicable Interventional

A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma

NCT03405610
View directory record Official record
Conditions
Musculoskeletal Injury, Fracture
Interventions
The Toolkit for Optimal Recovery after Injury
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 22, 2026, 4:10 AM EDT