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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fractures, Compression Clear all
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2010 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Phase 3 Interventional Results available

The Kiva® System as a Vertebral Augmentation Treatment

NCT01123512
View directory record Official record
Conditions
Spinal Fractures, Fractures, Compression, Back Injuries
Interventions
Vertebral augmentation
Device
Lead sponsor
Benvenue Medical, Inc.
Industry
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
15
States / cities
Encinitas, California • Mountain View, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2014 · Synced Sep 5, 2026, 9:01 PM EDT
Completed No phase listed Observational

SpineJack System Postmarket Registry

NCT04795765
View directory record Official record
Conditions
Osteoporotic Vertebral Compression Fractures
Interventions
SpineJack system, Balloon kyphoplasty, Vertebroplasty
Procedure
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years and older
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
12
States / cities
Encinitas, California • Larkspur, California • Stuart, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 5, 2026, 9:01 PM EDT
Withdrawn Phase 2 Interventional

A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women

NCT00787358
View directory record Official record
Conditions
Hip Fracture
Interventions
ZT-031, placebo
Drug · Other
Lead sponsor
Zelos Therapeutics
Industry
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2009 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation

NCT05205616
View directory record Official record
Conditions
Surgical Complication, Paresthesia, Fracture, Nerve Injury, Nerve Entrapments, Mandibular Nerve Injuries, Mandibular Hypoplasia, Mandibular Retrognathism, Mandibular Hyperplasia, Mandibular Prognathism
Interventions
Sonopet ultrasonic saw, Reciprocating saw
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 5, 2026, 9:01 PM EDT
Not listed Not applicable Interventional

Biological Allograft Chain Tissue Implant

NCT04064710
View directory record Official record
Conditions
Vertebral Body Compression Fracture(s)
Interventions
Vertebral Body Augmentation, Manual Surgical Instruments
Procedure · Device
Lead sponsor
Lenoss Medical
Industry
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Denver, Colorado • Manhasset, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs

NCT01871519
View directory record Official record
Conditions
Compression Fracture of Vertebral Body, Osteoporosis, Cancer
Interventions
Balloon kyphoplasty
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
65 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Fremont, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional

The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation

NCT01480167
View directory record Official record
Conditions
Painful Osteoporotic Vertebral Compression Fractures (VCF)
Interventions
Vertebral Augmentation (STABILIT), Non-operative Management
Device · Other
Lead sponsor
DFINE Inc.
Industry
Eligibility
21 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
6
States / cities
St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Phase 4 Interventional Results available

Anderson Circulating Tumor Cell Burden (CTCB) Study

NCT00819832
View directory record Official record
Conditions
Cancer, Spinal Disease, Vertebral Compression Fractures
Interventions
Kyphoplasty, Vertebroplasty, Cavity SpineWand
Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Sep 5, 2026, 9:01 PM EDT
Suspended Not applicable Interventional

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

NCT01693094
View directory record Official record
Conditions
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures, Trigger Finger
Interventions
Decision Aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Results available

THP Hip Fracture Plating System Study

NCT03870477
View directory record Official record
Conditions
Femur Fracture, Femur Fracture Intertrochanteric, Garden Grade I Subcapital Fracture of Femoral Neck, Garden Grade II Subcapital Fracture of Femoral Neck, Garden Grade III Subcapital Fracture of Femoral Neck, Garden Grade IV Subcapital Fracture of Femoral Neck
Interventions
THP Hip Fracture Plating System with telescoping lag screws
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures

NCT02625766
View directory record Official record
Conditions
LC Pelvic Fracture
Interventions
LC fracture surgical fixation, LC fracture non-operative management
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

OsseoFix™ Spinal Fracture Reduction System in Treating Spinal Compression Fracture

NCT00961714
View directory record Official record
Conditions
Vertebral Compression Fractures
Interventions
OsseoFix Spinal Fracture Reduction System
Device
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
50 Years to 105 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
11
States / cities
La Jolla, California • Boulder, Colorado • Littleton, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Phase 3 Interventional Results available

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

NCT01345019
View directory record Official record
Conditions
Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
Interventions
Denosumab, Zoledronic acid, Placebo to Denosumab, Placebo to zoledronic acid, Denosumab (for the open-label treatment phase)
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
1,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
79
States / cities
Tucson, Arizona • Fayetteville, Arkansas • Anaheim, California + 67 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Phase 4 Interventional

FREE Study - Fracture Reduction Evaluation

NCT00211211
View directory record Official record
Conditions
Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
Interventions
Balloon Kyphoplasty
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

NCT03651804
View directory record Official record
Conditions
Vertebral Compression Fracture, Facet Joint Pain
Interventions
Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids
Procedure · Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

CAFE Study - Cancer Patient Fracture Evaluation

NCT00211237
View directory record Official record
Conditions
Cancer, Spinal Fractures
Interventions
Balloon Kyphoplasty, Non Surgical Management
Device · Other
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
9
States / cities
Escondido, California • Boulder, Colorado • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 5, 2026, 9:01 PM EDT
Recruiting No phase listed Observational

Effect of 60-day Peripheral Nerve Stimulation (PNS) in Alleviating Pain and Improving Function After Acute Thoracolumbar Compression Fracture

NCT07079865
View directory record Official record
Conditions
Thoracolumbar Compression Fractures
Interventions
SPRINT PNS modulation system
Device
Lead sponsor
Saint Peters University Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Avenel, New Jersey • Morganville, New Jersey • Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Preliminary Review of Cold and Active Compression Therapy for Traumatic Calcaneus or Ankle Fractures

NCT02498717
View directory record Official record
Conditions
Ankle Fractures
Interventions
GameReady, RICE
Device · Other
Lead sponsor
AdventHealth
Other
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Stress Radiography for Pelvic Ring Injuries

NCT05876871
View directory record Official record
Conditions
Pelvic Fracture
Interventions
Pelvic Binder Radiography
Diagnostic Test
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Results available

Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures

NCT01383616
View directory record Official record
Conditions
Vertebral Compression Fracture
Interventions
Kyphon® Balloon Kyphoplasty (Kyphon Inc; Sunnydale, CA)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 100 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Not applicable Interventional

Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures

NCT03952182
View directory record Official record
Conditions
Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine, Burst Fracture of Thoracic Vertebra, Burst Fracture of Lumbar Vertebra
Interventions
Spinal Orthosis (LSO, TLSO), No orthosis
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Geriatric Lateral Compression 1 Pelvic Fractures

NCT05765669
View directory record Official record
Conditions
Lateral Compression 1 Pelvic Fracture
Interventions
Percutaneous screw fixation, Pain management, Physical therapy
Procedure · Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
60 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Coon Rapids, Minnesota • Saint Louis Park, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 5, 2026, 9:01 PM EDT