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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Free Air in Abdomen Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Device to Assist With Abdominal Access During Laparoscopic Surgery

NCT04392635
View directory record Official record
Conditions
Laparoscopic Surgery
Interventions
TauTona Pneumoperitoneum Assist Device (TPAD), Standard of Care (SOC)
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 23, 2026, 8:18 AM EDT
Withdrawn Not applicable Interventional

Warm and Humidified vs Cold and Dry Carbon Dioxide (CO2) Pneumoperitoneum

NCT03330067
View directory record Official record
Conditions
Pneumoperitoneum
Interventions
Cold and dry CO2 pneumoperitoneum, Warm and humidified CO2 pneumoperitoneum
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2023 · Synced Jul 23, 2026, 8:18 AM EDT
Recruiting Not applicable Interventional

Short Title: Standard vs. Lower Pressure Pneumoperitoneum

NCT06338865
View directory record Official record
Conditions
Laparoscopic Surgery
Interventions
Carbon dioxide, Bupivacaine, Oxycodone
Other · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Jul 23, 2026, 8:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Point of Care Ultrasound for Diagnosis of Abdominal Free Air

NCT03719872
View directory record Official record
Conditions
Free Air in Abdomen
Interventions
Pre-Operative Transabdominal Ultrasound, Post-Operative Transabdominal Ultrasound
Diagnostic Test
Lead sponsor
David Blehar
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Lower Pneumoperitoneum Pressure During Laparoscopic and Robotic Hysterectomy

NCT04125173
View directory record Official record
Conditions
Hysterectomy, Pneumoperitoneum
Interventions
Pneumoperitoneum pressure = 15mmHg, Pneumoperitoneum pressure = 12mm Hg, Pneumoperitoneum pressure = 10mmHg
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional Results available

Study of Carbon Dioxide Exchange Patterns During Robotic Prostatectomies

NCT02114164
View directory record Official record
Conditions
Prostate Cancer, Pneumoperitoneum
Interventions
AirSeal System, Standard Endopath
Device
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older · Male only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Jul 23, 2026, 8:18 AM EDT
Completed No phase listed Observational

Intraperative Assessment of Renal Perfusion Using Infrared Imaging

NCT00595179
View directory record Official record
Conditions
Kidney Transplantation
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2012 · Synced Jul 23, 2026, 8:18 AM EDT
Not listed Not applicable Interventional

Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.

NCT00286286
View directory record Official record
Conditions
Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity, Pneumoperitoneum
Interventions
Intraperitoneal Aerosolization System, IntraMyst
Device
Lead sponsor
Northgate Technologies
Industry
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
2
States / cities
Elk Grove Village, Illinois • Hoffman Estates, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 10, 2007 · Synced Jul 23, 2026, 8:18 AM EDT
Terminated Not applicable Interventional Results available

Ultralow Versus Standard Pneumoperitoneum Pressure

NCT03630393
View directory record Official record
Conditions
Prostate Cancer
Interventions
Pneumoperitoneum Pressure 6 mmHg, Pneumoperitoneum Pressure 15 mmHg
Other
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older · Male only
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional

Pneumoperitoneum Management With SurgiQuest AirSeal at Low vs. Higher Pressure ( PRESSURE )

NCT02541448
View directory record Official record
Conditions
Shoulder Pain
Interventions
SurgiQuest AIRSEAL® Insufflation System (AIS)
Device
Lead sponsor
Cynthia Harris
Industry
Eligibility
18 Years to 80 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Jul 23, 2026, 8:18 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Randomized Trial of Moderate vs Deep Neuromuscular Blockade During Laparoscopic Ventral Hernia Repair

NCT03201744
View directory record Official record
Conditions
Hernia, Ventral, Neuromuscular Blockade, Pneumoperitoneum
Interventions
Patients will be randomized to moderate (TOF 1-2) or deep (post tetanic count 1-2) relaxation. Low pressure insufflation (start pressure set at 8 mm Hg)
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 23, 2026, 8:18 AM EDT
Completed No phase listed Observational

Trendelenburg Study

NCT01979575
View directory record Official record
Conditions
Comparison of Non-invasive Monitors of Cardiac Function
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Jul 23, 2026, 8:18 AM EDT
Not listed Not applicable Interventional

Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial

NCT04858438
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Insufflation during surgery
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

AirSeal®Insufflation Trocar/CO2 Absorption Study

NCT02654808
View directory record Official record
Conditions
Gynecologic Diseases
Interventions
AirSeal trocar, Standard trocar
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 23, 2026, 8:18 AM EDT
Not yet recruiting Not applicable Interventional

Low Gas Pressure vs Standard Gas Pressure in Weight-Loss Surgery

NCT07710352
View directory record Official record
Conditions
Obesity & Overweight, Robotic Surgery, Pneumoperitoneum
Interventions
AirSeal Robotic Solution, Standard-pressure pneumoperitoneum (15 mmHg)
Device · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional Results available

A Comparative Study Between AirSeal, an Integrated Insufflation System, and Conventional Insufflation

NCT02075658
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
AirSeal® System-Interventional, Conventional Insufflator and Trocar
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jul 23, 2026, 8:18 AM EDT
Not yet recruiting Not applicable Interventional

Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair

NCT06737068
View directory record Official record
Conditions
Hernia, Hiatal, Pneumoperitoneum, Postoperative Pain, Shoulder Pain
Interventions
Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Jul 23, 2026, 8:18 AM EDT
Completed No phase listed Observational

Donor Recipient Kidney Function Following Open Surgical vs. Laparoscopic Kidney Donation

NCT00100516
View directory record Official record
Conditions
Kidney Transplantation
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 23, 2026, 8:18 AM EDT
Recruiting Not applicable Interventional

Low Pressure Pneumoperitoneum and Postoperative Ileus

NCT05344417
View directory record Official record
Conditions
Postoperative Ileus, Gastrointestinal Dysfunction
Interventions
Pneumoperitoneum Pressure, Neuromuscular blockade, Pneumoperitoneum insufflation device, Neuromuscular blockade reversal
Procedure · Device · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology

NCT02853591
View directory record Official record
Conditions
Pain, Pneumoperitoneum, Inflammation, Quality of Life
Interventions
Pneumoinsufflator mode and setting
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Jul 23, 2026, 8:18 AM EDT
Not listed Not applicable Interventional

The Impact of Low Pressure Pneumo in RARP II

NCT04394676
View directory record Official record
Conditions
Prostate Cancer
Interventions
Pressure applied during RARP
Procedure
Lead sponsor
Metro Health, Michigan
Other
Eligibility
40 Years and older · Male only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Jul 23, 2026, 8:18 AM EDT
Completed Not applicable Interventional

The Impact of Low Pressure Pneumo in RARP

NCT03370016
View directory record Official record
Conditions
Prostate Cancer
Interventions
Amount of Pneumoperitoneum Pressure applied during RARP
Procedure
Lead sponsor
Metro Health, Michigan
Other
Eligibility
40 Years and older · Male only
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Jul 23, 2026, 8:18 AM EDT
Not listed Not applicable Interventional

SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study)

NCT02262884
View directory record Official record
Conditions
Subcutaneous Emphysema
Interventions
SurgiQuest AirSeal Insufflation System (AIS), Conventional Insufflation System (CIS)
Device
Lead sponsor
SurgiQuest, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
St Louis, Missouri • Hackensack, New Jersey • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2016 · Synced Jul 23, 2026, 8:18 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Maneuvers to Reduce Laparoscopic Pain

NCT07583433
View directory record Official record
Conditions
Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
Interventions
Smoke Evacuation Group, Recruitment Breath Group, Control Group
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 23, 2026, 8:18 AM EDT