Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 23, 2026, 4:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Free Flap Reconstruction Clear all
Recruiting No phase listed Observational

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

NCT04098146
View directory record Official record
Conditions
Mandibular Reconstruction, Segmental Mandibular Defects
Interventions
Surgical Resection and Reconstruction
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2022 – 2030
U.S. locations
5
States / cities
Jacksonville, Florida • Chicago, Illinois • New Hyde Park, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Jul 23, 2026, 4:04 AM EDT
Not listed No phase listed Observational

Skin Flap Visible Light Spectroscopy (VLS) Oximetry for Monitoring Free-Flap Ischemia During Breast Reconstruction and Recovery

NCT01173133
View directory record Official record
Conditions
Ischemia
Interventions
Not listed
Lead sponsor
Spectros Corporation
Industry
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2011 · Synced Jul 23, 2026, 4:04 AM EDT
Completed No phase listed Observational

Leg Function and ADL After ALT Reconstruction for Head and Neck Cancer

NCT02332161
View directory record Official record
Conditions
Free Tissue Flaps, Head and Neck Neoplasms
Interventions
surveys, evaluative tests for leg function
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Not applicable Interventional

Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps

NCT03340038
View directory record Official record
Conditions
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Carcinoma, Trauma
Interventions
Non-ICU Specialty ward
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Jul 23, 2026, 4:04 AM EDT
Completed No phase listed Observational

Monitoring of Tissue Transfer Flaps by Modulated Imaging (MI) Spectroscopy

NCT00633503
View directory record Official record
Conditions
Reconstructive Surgical Procedures, Tissue Transplantation
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
2
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Phase 4 Interventional Results available

Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management

NCT04284930
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Depobupivacaine, OnQ pump, 0.25% Bupivacaine
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Jul 23, 2026, 4:04 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Regional Anesthesia Block in Fibula Free Flap Reconstruction

NCT03906838
View directory record Official record
Conditions
Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative, Head and Neck Neoplasms
Interventions
Ropivacaine injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Jul 23, 2026, 4:04 AM EDT
Withdrawn Not applicable Interventional

Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy

NCT04063410
View directory record Official record
Conditions
Mammoplasty Patient
Interventions
Angiography, MRI-Based Angiogram, Quality-of-Life Assessment
Procedure · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction

NCT04777591
View directory record Official record
Conditions
Postoperative Pain, Breast Reconstruction
Interventions
Liposomal bupivacaine TAP block, Bupivacain
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Withdrawn Not applicable Interventional

Integrated Imaging System for In Vivo Visualization of Free Flap Perfusion Using Indocyanine Dye

NCT03625765
View directory record Official record
Conditions
Breast Reconstruction
Interventions
SmartGoggles
Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Not listed No phase listed Observational

Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03872544
View directory record Official record
Conditions
Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds and Injuries, Wounds, Disturbance of Wound Healing, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Jul 23, 2026, 4:04 AM EDT
Not listed No phase listed Observational

Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03880188
View directory record Official record
Conditions
Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing, Disturbance of Wound Healing, Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Jul 23, 2026, 4:04 AM EDT
Recruiting Not applicable Interventional

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

NCT04003038
View directory record Official record
Conditions
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
Interventions
Negative Pressure Wound Therapy, Wound Care Management
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Not applicable Interventional

Pain Management Following TRAM Flap for Breast Reconstruction

NCT00500565
View directory record Official record
Conditions
Breast Cancer
Interventions
Saline, Bupivicaine
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 10, 2013 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Phase 4 Interventional Results available

Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction

NCT03700970
View directory record Official record
Conditions
Breast Reconstruction, Anesthesia, Transverse Abdominis Plane Block
Interventions
Liposomal bupivacaine, Regular bupivacaine
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 23, 2022 · Synced Jul 23, 2026, 4:04 AM EDT
Completed No phase listed Observational

Functional and Aesthetic Outcomes After Mandible Reconstruction With Fibula Osteomyocutaneous Free Flaps

NCT02572869
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
physical exam, questionnaires
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
25 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Basking Ridge, New Jersey • Harrison, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jul 23, 2026, 4:04 AM EDT
Recruiting Phase 4 Interventional

Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction

NCT06784999
View directory record Official record
Conditions
Free Flap Reconstruction
Interventions
sufentanil, methadone
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Phase 4 Interventional Results available

Multimodal Pain Study in Free Flap Patients

NCT04246697
View directory record Official record
Conditions
Head and Neck Cancer, Analgesia
Interventions
Tylenol, Oxycodone, Morphine, Gabapentin, toradol, Bupivacaine
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 23, 2026, 4:04 AM EDT
Terminated Phase 3 Interventional

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

NCT04176419
View directory record Official record
Conditions
Postoperative Pain Control, Opioid Consumption
Interventions
Ketamine, Placebo Ketamine, Lidocaine, Placebo Lidocaine, Acetaminophen, Placebo Acetaminophen, Gabapentin, Placebo Gabapentin, Celecoxib, Placebo Celecoxib
Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Not listed Phase 4 Interventional

Role of TXA in Patients Undergoing Breast Free Flap Reconstruction

NCT06428682
View directory record Official record
Conditions
Breast Cancer, Blood Loss, Surgical
Interventions
Tranexamic acid, Placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Not listed Not applicable Interventional

Early Feeding After Oral Cavity Reconstruction

NCT04787939
View directory record Official record
Conditions
Head and Neck Cancer, Free Tissue Transfer
Interventions
Early Feeding
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Recruiting Not applicable Interventional

A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

NCT05889091
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
HRQOL instruments, LENT SOMA instrument
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 23, 2026, 4:04 AM EDT
Terminated Not applicable Interventional

Free Flap Breast Reconstruction Using Virtual Surgical Planning and 3-D Modeling

NCT03949491
View directory record Official record
Conditions
Breast Reconstruction
Interventions
3D medical models
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Jul 23, 2026, 4:04 AM EDT
Completed Phase 3 Interventional Results available

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

NCT02601027
View directory record Official record
Conditions
Breast - Female
Interventions
Transversus Abdominis Plane (TAP) block, Nimbus Infusion Pump IV Administration, Bupivacaine infusion, Acetominophen, Hydromorphone, Oxycodone, Ondansetron
Procedure · Device · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Jul 23, 2026, 4:04 AM EDT