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Showing 217–240 of 322 matching trials from the live ClinicalTrials.gov search.
Recruiting No phase listed Observational Accepts healthy volunteers

Apple Health Study

NCT06958523
Conditions
Mental Health, Sleep, Exercise, Hormones, Metabolic Health, Hearing, Aging, Lifestyle Factors, Functional Capacity, Neurological Conditions, General Health, Wellbeing, Women's Health
Interventions
Not listed
Lead sponsor
Apple Inc.
Industry
Eligibility
18 Years and older
Enrollment
500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women

NCT07222111
Conditions
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
Interventions
Dried plums
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
60 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Prediabetes, Healthy (Controls)
Interventions
Ketone Monoester (KE), Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Mind-body Interventions for Healthy Aging

NCT03626532
Conditions
Aging
Interventions
Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
65 Years to 85 Years
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Obesity
Interventions
Vibegron, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

MRI Biomarkers and Exercise

NCT02729428
Conditions
Cerebrovascular Circulation
Interventions
MRI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

A "Stand Up and Move More" Intervention for Older Adults

NCT03412084
Conditions
Sedentary Lifestyle
Interventions
Stand up and move more
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
56 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Aging
Interventions
rapamycin
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
70 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Antonio, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

Human Observatory Study

NCT07646782
Conditions
Aging, Mortality, All-cause Mortality, Life Expectancy, Cardiovascular Diseases, Neoplasms, Cognitive Dysfunction, Metabolic Syndrome, Frailty, Musculoskeletal Disease, Neurodegenerative Disease, Dementia, Activities of Daily Living, Health Related Quality of Life, Environmental Exposure, Occupational Diseases, Health Equity, Social Determinants of Health, Physical Disability
Interventions
Multi-Domain Ecological and Clinical Data Linkage
Other
Lead sponsor
Longevity Metrics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2099
U.S. locations
1
States / cities
Boulder, Colorado
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life

NCT07719088
Conditions
Aging, Longevity, Biomarkers of Aging
Interventions
Psilocybin (Usona Institute)
Drug
Lead sponsor
Charles Raison
Other
Eligibility
60 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Edwards, Colorado
Conditions
Functional Aging, Subjective Cognitive Concerns, Compensation Strategies, Brain Health Activities
Interventions
Intervention
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Recruiting No phase listed Observational Accepts healthy volunteers

Influence of Brain Oscillation-Dependent TMS on Motor Function

NCT03288220
Conditions
Healthy, Stroke, Normal Physiology, Aging
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 120 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals

NCT03595774
Conditions
Aging, Sarcopenia
Interventions
Beet root juice
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
65 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Entorhinal Cortex and Aerobic Exercise in Aging

NCT02775760
Conditions
Aging
Interventions
Cardiovascular endurance, Strength, balance, and flexibility
Behavioral
Lead sponsor
Boston University
Other
Eligibility
60 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Plantar Fasciitis, Chronic
Interventions
minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
Device
Lead sponsor
University of South Florida
Other
Eligibility
50 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Nutritional Strategies for Metabolic Health in Aging

NCT04282603
Conditions
Sarcopenic Obesity
Interventions
Weight Loss and Weight Maintenance
Combination Product
Lead sponsor
University of Alaska Fairbanks
Other
Eligibility
60 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fairbanks, Alaska
Completed Not applicable Interventional Results available

Utilizing Protein During Weight Loss to Impact Physical Function

NCT03074643
Conditions
Obesity, Weight Loss, Diet Modification, Aging, Weight Change, Body, Dietary Habits
Interventions
Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6, Protein supplement for months 0-6, Protein supplement for follow-up months 7-18
Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Brain Injuries, Traumatic, Executive Dysfunction
Interventions
Home-based telehealth GOALS, In-person GOALS
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline

NCT06466655
Conditions
Middle-aged Adults, Major Depressive Disorder
Interventions
MitoTempol, Lactated Ringer's (control)
Drug
Lead sponsor
University of Delaware
Other
Eligibility
40 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Alzheimer Disease, Dementia
Interventions
Brain Safe App, Attention Control App
Other
Lead sponsor
Indiana University
Other
Eligibility
60 Years and older
Enrollment
706 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Community-based Functional Fitness for Adults Aging With Mobility Disability

NCT07283510
Conditions
Mobility Disability, Older Adults
Interventions
Functional Fitness
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
60 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lawrence, Kansas
Recruiting Phase 4 Interventional Accepts healthy volunteers

Bioenergetic Effects of Aging and Menopause (BEAM)

NCT04043520
Conditions
Menopause, Obesity, Abdominal, Aging, Weight Gain
Interventions
GnRH antagonist, Estrogen Product, Placebo estradiol, Placebo GnRH antagonist
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults

NCT05488652
Conditions
Time Restricted Eating
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Not applicable Interventional Accepts healthy volunteers

Functional Assessment and Muscle Evaluation Through Exercise Trial

NCT03166150
Conditions
Urinary Incontinence
Interventions
Multi-modal rehabilitation program, Pelvic Floor Physical therapy
Other
Lead sponsor
Howard University
Other
Eligibility
65 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia