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ClinicalTrials.gov public records Last synced Oct 24, 2026, 3:15 AM EDT

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Showing 97–120 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Functional Aging Clear all
Not listed Not applicable Interventional

Noise-Enhanced Sensory Function in Elders at Risk for Falls

NCT00421759
View directory record Official record
Conditions
Aging, Somatosensory Deficit
Interventions
Vibrating Insoles
Device
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
70 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2009 · Synced Oct 24, 2026, 3:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health Outcomes After Participating in Exercise (HOPE)

NCT03430115
View directory record Official record
Conditions
Weight Loss, Obesity, Aging
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive

NCT00328055
View directory record Official record
Conditions
Aging
Interventions
AD-Easy (Advance Directive-Easy), AD-Standard (Advance Directive-Standard)
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2011 · Synced Oct 24, 2026, 3:15 AM EDT
Not yet recruiting Not applicable Interventional

Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women

NCT07406243
View directory record Official record
Conditions
Aging, Postmenopause
Interventions
Mitoquinone (MitoQ), Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
60 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physical Activity and Cognitive Function in Older Adults: A Novel Role for GPLD1

NCT04645134
View directory record Official record
Conditions
Aging, Cognitive Dysfunction
Interventions
Brain Health Assessments
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
65 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Oct 24, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Aging With a Ketone Ester for Function in Frailty

NCT06645847
View directory record Official record
Conditions
Frail Elderly, Aging, Immune Function, Muscle Function
Interventions
Ketone ester, Placebo Comparator: Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Novato, California • Farmington, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Aerobic Exercise and Cerebrovascular Function

NCT03803904
View directory record Official record
Conditions
Aging
Interventions
Spin
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
View directory record Official record
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Strengthening Skills Behavioral Intervention for Adults With Autism Spectrum Disorder

NCT04802434
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Strengthening Skills Program, PEERS Social Skills Program
Behavioral
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
21 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly

NCT00298558
View directory record Official record
Conditions
Aging, Healthy
Interventions
Cognitive Training
Behavioral
Lead sponsor
Carelon Research
Other
Eligibility
65 Years and older
Enrollment
2,832 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2010
U.S. locations
7
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 24, 2026, 3:15 AM EDT
Not yet recruiting Not applicable Interventional

Improving Functioning Among Aging Women Veterans

NCT06580470
View directory record Official record
Conditions
Menopause
Interventions
Tailored Cognitive Behavioral Therapy for Menopause
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Perry Point, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Study of Exercise and Memory Function

NCT02057354
View directory record Official record
Conditions
Aging
Interventions
Aerobic Exercise, Non-Aerobic Exercise
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 85 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults

NCT04074941
View directory record Official record
Conditions
Hypertension, Physical Disability, Aging
Interventions
Dietary intervention
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

NCT00608062
View directory record Official record
Conditions
Arterial Stiffening, Aging, Menopause
Interventions
GnRHant - Ganirelix acetate, Transdermal estradiol patch, Transdermal placebo patch
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 24, 2026, 3:15 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Tau PET Imaging in the NACC Study Cohort

NCT03189485
View directory record Official record
Conditions
Normal Controls, MCI
Interventions
the radiotracer 18F-AV-1451
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
60 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life

NCT01030419
View directory record Official record
Conditions
Aging
Interventions
Home-based, DVD-delivered physical activity, Usual care/Wait list
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years to 85 Years
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)

NCT07204444
View directory record Official record
Conditions
Older Adults, Mental Health, Depression, Loneliness, Social Isolation, Suicide Ideations, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness, Help-Seeking Behavior, Suicide Risk
Interventions
standardized and manualized warm calls from providers trained in the BE training, standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
671 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00427193
View directory record Official record
Conditions
Aging
Interventions
Caloric Restriction (CR), Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 50 Years
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate and Exercise Performance in Middle to Older Aged Adults

NCT03371966
View directory record Official record
Conditions
Aging
Interventions
High Nitrate Beetroot Juice, Low Nitrate Beetroot Juice
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
40 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Oct 24, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

NCT05000515
View directory record Official record
Conditions
Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
High-resistance inspiratory muscle strength training, Aerobic exercise
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS

NCT05996575
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
55 Years to 85 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Carlsbad, California • Costa Mesa, California • Escondido, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Nicotine and Attention on Frequency Tuning in Auditory Cortex

NCT05018117
View directory record Official record
Conditions
Aging
Interventions
Nicotine gum, Placebo gum
Drug · Other
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 24, 2026, 3:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

NCT03473145
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Health Coaching, activPAL inclinometer, Tools to Prompt Standing or Prompt Sit-to-Stand Transitions.
Behavioral · Device · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 24, 2026, 3:15 AM EDT