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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:53 AM EDT

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Showing 1–24 of 205 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: GI Symptoms Clear all
Completed Phase 1 Interventional

A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

NCT02128581
View directory record Official record
Conditions
Obesity, Diabetes, Roux-en-Y Gastric Bypass
Interventions
Exendin-9,39, Saline
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radicle GI Health 24: A Study of Health and Wellness Products on GI Health and Related Health Outcomes

NCT06376695
View directory record Official record
Conditions
Abdominal Pain, GI Disorders, Digestion
Interventions
Radicle GI Health Placebo Control Form 1, Radicle GI Health Active Study Product 1.1 Usage, Radicle GI Health Placebo Control Form 2, Radicle GI Health Active Study Product 2.1 Usage, Radicle GI Health Placebo Control Form 3, Radicle GI Health Active Study Product 3.1 Usage, Radicle GI Health Placebo Control Form 4, Radicle GI Health Active Study Product 4.1 Usage, Radicle GI Health Placebo Control Form 5, Radicle GI Health Active Study Product 5.1 Usage, Radicle GI Health Placebo Control Form 7, Radicle GI Health Active Study Product 7.1 Usage, Radicle GI Health Placebo Control 7.2, Radicle GI Health Active Study Product 7.2.1 Usage, Radicle GI Health Placebo Control 7.3.0, Radicle GI Health Active Study Product 7.3.1 Usage, Radicle GI Health Placebo Control 7.4.0, Radicle GI Health Active Study Product 7.4.1 Usage
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
4,607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 24, 2026, 4:53 AM EDT
Terminated No phase listed Observational

Evaluation of Gastrointestinal Symptoms and Quality of Life in Patients With Sphincter of Oddi Dysfunction

NCT01410071
View directory record Official record
Conditions
Sphincter of Oddi Dysfunction, Abdominal Pain
Interventions
Not listed
Lead sponsor
Wisconsin Center for Advanced Research
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 4, 2011 · Synced Oct 24, 2026, 4:53 AM EDT
Not listed No phase listed Observational

Pediatric Acute Gastrointestinal Bleeding Registry

NCT03090945
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Interventions
This is an obsevational cohort study
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Chicago, Illinois • Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 24, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

NCT07421596
View directory record Official record
Conditions
Gastrointestinal Symptoms, Digestive Health, Gut Health
Interventions
PhytoPower 1 and PhytoPower 2
Dietary Supplement
Lead sponsor
SF Research Institute, Inc.
Network
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Detection of Blood in the GI Lumen With HemoPill Acute

NCT07868068
View directory record Official record
Conditions
Upper GI Bleeding
Interventions
HemoPill acute
Device
Lead sponsor
Stony Brook University
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Phase 2Phase 3 Interventional Results available

NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies

NCT04955730
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Negative Pressure Wound Therapy
Device
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Radicle GI Health™ RFY: A Study Assessing the Impact of DAO Supplementation on Gastrointestinal and Other Histamine Intolerance Symptoms

NCT07835776
View directory record Official record
Conditions
GI Health
Interventions
Active GI Health Product 1, Placebo GI Health Control
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Multistrain Probiotic for Functional Constipation

NCT01618617
View directory record Official record
Conditions
Functional Constipation
Interventions
High dose Multistrain probiotic, 100 billion cfu/day, Low dose Multistrain probiotic, 15 billion cfu/day
Dietary Supplement
Lead sponsor
Renew Life Formulas Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2012 · Synced Oct 24, 2026, 4:53 AM EDT
Recruiting Phase 2 Interventional

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

NCT07795749
View directory record Official record
Conditions
Esophageal Carcinoma, Gastric Cancer (Diagnosis), Colorectal Adenocarcinoma, Appendiceal Adenocarcinoma, Small Bowel Adenocarcinoma, Hepatobiliary Carcinoma in Situ
Interventions
Paclitaxel Q2W, Paclitaxcel Q3W
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers Results available

The Efficacy of Probiotics to Reduce Antepartum Group B Streptococcus Colonization.

NCT03696953
View directory record Official record
Conditions
Group B Streptococcus Carrier in Childbirth, Gastrointestinal Symptoms
Interventions
Florajen3
Biological
Lead sponsor
Marquette University
Other
Eligibility
18 Years and older · Female only
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 24, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Radicle GI HealthTM VNB: A Study Assessing the Impact of Health and Wellness Products on Constipation and Related Health Outcomes

NCT07713810
View directory record Official record
Conditions
Constipation
Interventions
Placebo GI Health Control, Active GI Health Product
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Study Evaluating the Impact of a Prebiotic Soda on Gastrointestinal Symptoms in Users of GLP-1 Agonists

NCT07744360
View directory record Official record
Conditions
GI Symptoms
Interventions
Prebiotic Soda
Other
Lead sponsor
Olipop, PBC
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional

A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders

NCT01116388
View directory record Official record
Conditions
Autism, Gastrointestinal Symptoms
Interventions
GFCF product with GFCF diet, product containing gluten and casein (milk protein) with GFCF diet
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.

NCT01477320
View directory record Official record
Conditions
Gastrointestinal Hemorrhage, Clostridium Difficile Colitis
Interventions
Pantoprazole 40 mg IV daily and tube feed., Placebo and tube feed
Drug · Other
Lead sponsor
Mohamed Saad
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 24, 2026, 4:53 AM EDT
Completed No phase listed Observational

Neurohumoral Control of Intestinal Electrical and Mechanical Activity

NCT00852553
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2012
U.S. locations
2
States / cities
Sacramento, California • Reno, Nevada
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 24, 2026, 4:53 AM EDT
Terminated No phase listed Observational

Left Atrial Appendage Closure With WATCHMAN FLX Device in Recurrent Gastrointestinal Bleeding: The GI-FLX Registry

NCT06052358
View directory record Official record
Conditions
Atrial Fibrillation, GI Bleeding
Interventions
LAAC with Watchman FLX device
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Overland Park, Kansas • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Capsule Endoscopy for HEmorrhage in the ER

NCT03458000
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding
Interventions
PillCam UGI, Standard of Care
Device · Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional

A Study to Evaluate the Effects of a Fiber Supplement on Gut Health

NCT07755735
View directory record Official record
Conditions
Gut Health, Bloating, Irregular Bowel Movements, Gastrointestinal Symptoms
Interventions
Active Supplement, Placebo Comparator
Dietary Supplement
Lead sponsor
Belli Welli Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Phase 1 Interventional Results available

Safety Study of Octreotide Injection to Prevent GI Bleeding in Patients With Left Ventricular Assist Device (LVAD)

NCT01707225
View directory record Official record
Conditions
Gastrointestinal Bleeding
Interventions
Octreotide LAR Depot
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC)

NCT00390182
View directory record Official record
Conditions
Gastrointestinal Neoplasms, Ovarian Neoplasms
Interventions
Gemcitabine
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 24, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Validating M.D. Anderson Symptom Inventory (MDASI-GI) in GI Cancer Patients Under Chemotherapy

NCT00849979
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
Questionnaire, Interview
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 24, 2026, 4:53 AM EDT
Withdrawn Not applicable Interventional

Pendulum D2D Glucose Control for Adults With Type 2 Diabetes

NCT04228003
View directory record Official record
Conditions
Type2 Diabetes, Gastrointestinal Symptoms
Interventions
Pendulum Glucose Control formulation for T2D
Dietary Supplement
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 24, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Psychological Prehabilitation for Complex Gastrointestinal Surgery

NCT07865052
View directory record Official record
Conditions
Post-traumatic Stress Symptoms, Anxiety, Depression Disorder, Gastrointestinal Disease
Interventions
PREPARE-GI
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 24, 2026, 4:53 AM EDT