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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gait Impairment Clear all
Not yet recruiting Not applicable Interventional

Clinical Efficacy of Exoskeleton Assistance for Individuals Post-Stroke

NCT06064604
View directory record Official record
Conditions
Stroke
Interventions
Control, Hip Exoskeleton, Ankle Exoskeleton
Other · Device
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

NCT06821568
View directory record Official record
Conditions
Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
Interventions
Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years to 90 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Measurement and Training of Dual-Task of Gait in Persons With Multiple Sclerosis

NCT03536299
View directory record Official record
Conditions
Multiple Sclerosis, Gait Disorders, Neurologic, Cognitive Impairment
Interventions
Dual-task gait, Single-task gait
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Randomized Trial to Evaluate Ampyra for Gait Impairment in Parkinson's Disease

NCT01491022
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Ampyra first, then Placebo, placebo first, then Ampyra
Drug
Lead sponsor
University of Miami
Other
Eligibility
45 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Jun 10, 2026, 2:08 PM EDT
Not yet recruiting Not applicable Interventional

Cognitive Integrated Motor Training (CM) to Improve Gait and Balance and Reduce Falls in Older Adults With Mild Cognitive Impairment

NCT06719297
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Personalized cognitive-sensorimotor VR/MR training, Standard of Care
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
65 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

REEV SENSE for Gait Analysis in Post-stroke Gait Impairment (SENS-AG)

NCT06234878
View directory record Official record
Conditions
Stroke, Gait Disorders, Neurologic
Interventions
REEV SENSE, Motion capture system
Device
Lead sponsor
REEV LLC
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Enrolling by invitation Not applicable Interventional

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder

NCT06374264
View directory record Official record
Conditions
Neuromyelitis Optica Spectrum Disorder
Interventions
MR-C-014
Device
Lead sponsor
MedRhythms, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Active, not recruiting Not applicable Interventional

Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

NCT04675398
View directory record Official record
Conditions
Parkinson Disease
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm

NCT03440112
View directory record Official record
Conditions
Parkinson Disease
Interventions
Clarithromycin (Not used as of 4/2020), Placebo (Not used as of 4/2020), Transdermal flumazenil (Added 4/2020), Placebo (Added 4/2020)
Drug
Lead sponsor
Nicolaas Bohnen, MD, PhD
Other
Eligibility
50 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

NCT00526630
View directory record Official record
Conditions
Parkinson's Disease, Gait Impairment
Interventions
Methylphenidate (MPD), Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
35 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Post-stroke Gait Rehab

NCT03666533
View directory record Official record
Conditions
Stroke, Gait Impairment
Interventions
Active transcranial Direct Current Stimulation, Sham transcranial Direct Current Stimulation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional

MINT Conditioning to Improve Gait

NCT07041775
View directory record Official record
Conditions
Stroke, Stroke Gait Rehabilitation
Interventions
myoelectric interface for neurorehabilitation (MINT) conditioning, One muscle myoelectric feedback
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Chicago, Illinois • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional

Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease

NCT06484244
View directory record Official record
Conditions
Alzheimers Disease, Mild Cognitive Impairment
Interventions
5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
Other
Lead sponsor
Emory University
Other
Eligibility
50 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Terminated Not applicable Interventional Results available

A Multisite Exploration of Balance Perturbations With and Without Body Weight Support

NCT05110300
View directory record Official record
Conditions
Stroke, Stroke, Acute, Balance; Distorted, Balance; Impairment, Gait, Unsteady
Interventions
Body weight support system control group, Body weight support system with balance perturbations
Device
Lead sponsor
Gaylord Hospital, Inc
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Wallingford, Connecticut • Washington D.C., District of Columbia • Sandwich, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Active, not recruiting Phase 1 Interventional

Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease

NCT05022147
View directory record Official record
Conditions
Parkinson Disease, Gait Disorders, Neurologic, Disease Progression, Subthalamic Nucleus, Accidental Fall, Deep Brain Stimulation
Interventions
High-Frequency-Only Stimulation, Low-Frequency-Only Stimulation, Alternating, 50 sec High-Frequency, 10 sec Low-Frequency Stimulation, Alternating, 50 sec High-Frequency, 50 sec Low-Frequency Stimulation, Alternating, 10 sec High-Frequency, 50 sec Low-Frequency Stimulation, Alternating, 10 sec High-Frequency, 10 sec Low-Frequency Stimulation, OFF Dopaminergic Medication, ON Dopaminergic Medication
Device · Drug
Lead sponsor
James Liao
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Balancing Act: Impact on Falls in Older Adults With Vision Impairment

NCT02074488
View directory record Official record
Conditions
Postural Balance
Interventions
Balancing Act exercise curriculum, Informational Brochure
Other
Lead sponsor
University of Maine
Other
Eligibility
62 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Biddeford, Maine • Orono, Maine • Portland, Maine
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jun 10, 2026, 2:08 PM EDT
Not yet recruiting Not applicable Interventional

Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity

NCT07554443
View directory record Official record
Conditions
Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, Fatigue, Balance Disorders, Physical Activities
Interventions
External, lower limb sensory prosthesis
Device
Lead sponsor
RxFunction Inc.
Industry
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Not yet recruiting Not applicable Interventional

Engaging Kids With Robotic Exoskeletons and Gamification

NCT06647082
View directory record Official record
Conditions
Genu Recurvatum, Crouch Gait
Interventions
Pediatric Knee Exoskeleton
Device
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
4 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 4 Interventional

Cholinergic Neurotransmission in Mobility and Cognition in Parkinson Disease

NCT03840837
View directory record Official record
Conditions
Parkinson Disease, Parkinson Disease Dementia
Interventions
Rivastigmine transdermal patch
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dopaminergic Dysfunction in Late-Life Depression

NCT04469959
View directory record Official record
Conditions
Late Life Depression, Cognitive Decline, Depressive Disorder, Treatment-Resistant, Levodopa, Gait Impairment
Interventions
L-Dopa, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Treatment of Hemiparetic Gait Impairments Using Telehealth With the Moterum iStride Solution™

NCT04434313
View directory record Official record
Conditions
Telemedicine, Gait, Hemiplegic, Gait Disorders, Neurologic, Stroke, Orthotic Devices, Gait Analysis
Interventions
Delivery of iStride™ device gait treatment using telemedicine
Device
Lead sponsor
Moterum Technologies, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Jun 10, 2026, 2:08 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Wearable Gait Sensors

NCT06628934
View directory record Official record
Conditions
Spinocerebellar Ataxia
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Not yet recruiting Not applicable Interventional

Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors

NCT07250425
View directory record Official record
Conditions
Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic, Post Stroke Fatigue, Motor Recovery, Walking Difficulty, Balance Impairment, Falls Prevention, Hemiparesis, Mobility Limitation
Interventions
Rise&Walk InHome by Healing Innovations
Device
Lead sponsor
Healing Innovations
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jun 10, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Modulation of GABA-A Receptors in Parkinson Disease-Flumazenil Arm

NCT03462641
View directory record Official record
Conditions
Parkinson Disease
Interventions
Flumazenil, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Jun 10, 2026, 2:08 PM EDT