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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

Memantine Treatment Study of Pathological Gambling

NCT00585169
Conditions
Pathological Gambling
Interventions
Memantine Hydrochloride
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Conditions
Gambling, Mental Health
Interventions
Cognitive behavior therapy, Contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Pathological Gambling
Interventions
Ecopipam
Drug
Lead sponsor
Emalex Biosciences Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Los Angeles, California • New Haven, Connecticut • Iowa City, Iowa + 1 more
Completed Phase 2 Interventional Results available

Tolcapone Treatment of Pathological Gambling

NCT00927563
Conditions
Pathological Gambling
Interventions
Tolcapone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional

Gambling and Brief Interventions

NCT00183599
Conditions
Gambling
Interventions
5 Minutes of Simple Advice, Motivational Enhancement Therapy (MET), Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2007
U.S. locations
6
States / cities
Bridgeport, Connecticut • Farmington, Connecticut • Hartford, Connecticut + 3 more
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Drug Treatment for Pathologic Gambling Disorder

NCT00053677
Conditions
Gambling
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Gambling
Interventions
10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Pathological Gambling
Interventions
Motivational Enhancement Therapy (MET), Cognitive-Behavioral Therapy (CBT)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Gambling
Interventions
Referral to Gamblers Anonymous, Cognitive behavioral therapy, Cognitive behavioral self-help manual
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Gambling Problem
Interventions
Text messages
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Phase 2 Interventional Results available

Milk Thistle in Pathological Gambling

NCT02337634
Conditions
Pathological Gambling, Gambling Disorder
Interventions
Placebo, Milk Thistle
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Detecting a Reward Signal in the Motor Cortex

NCT00422071
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Gambling Disorder, Gambling Problem
Interventions
Contingency management, Cognitive behavioral therapy/ treatment as usual
Behavioral
Lead sponsor
East Tennessee State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Johnson City, Tennessee
Conditions
Gambling Disorder
Interventions
mHealth App
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Gambling
Interventions
Cognitive behavioral therapy (CBT), Contingency management (CM), Psychoeducation therapy, Case management, Gamblers Anonymous (GA)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Pathological Gambling
Interventions
CBT, CMBT
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Gambling, Alcohol Consumption, Cannabis
Interventions
Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
17 Years to 24 Years
Enrollment
361 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Impulse Control Disorder, Parkinson Disease
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Susceptibility to Pathological Gambling

NCT01528982
Conditions
Pathological Gambling
Interventions
Mindfulness, Cognition
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 29 Years
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Gambling, Tobacco Use Disorder
Interventions
N Acetyl Cysteine, Sugar Pill
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Recruiting Not applicable Interventional

Change 4 Better (C4B)

NCT06963931
Conditions
Problem Gambling
Interventions
Change4Better (C4B) mobile app
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Denver, Colorado • New Haven, Connecticut • Norwalk, Connecticut + 3 more
Conditions
Healthy
Interventions
Nitrofurantoin Monohydrate/Macrocrystals Capsules 100 mg, Macrobid® Capsules 100 mg
Drug
Lead sponsor
Mylan Pharmaceuticals Inc
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2002
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Pathological Gambling
Interventions
Bupropion, Placebo
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Iowa City, Iowa
Terminated Phase 3 Interventional Results available

Topiramate in the Treatment of Pathological Gambling

NCT00245583
Conditions
Pathological Gambling
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
New York, New York