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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 493 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Gastroesophageal Reflux Disorder Clear all

Conditions: Barretts Esophagus With Dysplasia
Interventions: Alginates; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Non-acid Reflux Disease
Interventions: anti-reflux surgery; Procedure
Lead sponsor: United States Naval Medical Center, Portsmouth; Federal
Eligibility: 17 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Portsmouth, Virginia

Conditions: Gastroesophageal Reflux, Esophageal Reflux, Gastroesophageal Reflux Disease, GERD
Interventions: Laparoscopic Hill Repair, Laparoscopic Nissen Repair; Procedure
Lead sponsor: Swedish Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Barrett's Esophagus, Gastroesophageal Reflux Disease
Interventions: Not listed
Lead sponsor: Midwest Biomedical Research; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Dysphagia, Gastroesophageal Reflux
Interventions: Not listed
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Non-erosive Reflux Disease, Gastroesophageal Reflux
Interventions: Proton Pump Inhibitor (PPI) Therapy, Sucralfate; Drug
Lead sponsor: LCMC Health; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: New Orleans, Louisiana

Conditions: Cerebral Palsy, GERD
Interventions: Baclofen, placebo; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Apparent Life Threatening Event, Gastroesophageal Reflux, Aspiration
Interventions: Rice cereal, Enfamil AR; Dietary Supplement
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 0 Years to 1 Year
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoporosis, Achlorhydria, GERD, Hip Fracture
Interventions: Omeprazole; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Heartburn, Gastroesophageal Reflux Disease
Interventions: Dexlansoprazole; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Eosinophilic Esophagitis, Gastroesophageal Reflux Disease, EE, GERD
Interventions: Esomeprazole, Budesonide; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Gastroesophageal Reflux Disease, Eosinophilic Esophagitis
Interventions: Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms; Drug
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: Rabeprazole sodium, Esomeprazole; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 1,397 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 85
States / cities: Huntsville, Alabama • Tucson, Arizona • Little Rock, Arkansas + 73 more

Conditions: Nasal Polyps, Gastroesophageal Reflux
Interventions: lansoprazole; Drug
Lead sponsor: Head and Neck Surgery Associates; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Vesicoureteral Reflux
Interventions: Not listed
Lead sponsor: Stanford University; Other
Eligibility: 3 Years to 16 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Stanford, California

Conditions: Varicose Veins
Interventions: Bright Tip Laser Fiber, Bare Tip Laser Fiber; Device
Lead sponsor: Vascular Solutions LLC; Industry
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 7
States / cities: Dothan, Alabama • Scottsdale, Arizona • Hollywood, Florida + 4 more

Conditions: Gastroesophageal Reflux
Interventions: pantoprazole sodium enteric-coated spheroid; Drug
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer; Industry
Eligibility: 1 Year to 5 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 36
States / cities: Mobile, Alabama • Phoenix, Arizona • Oakland, California + 32 more

Conditions: GERD, Acid Reflux, Treatment
Interventions: Omega-Cuff; Device
Lead sponsor: Aplos Medical; Industry
Eligibility: 22 Years to 74 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Scottsdale, Arizona • Los Angeles, California • Austin, Texas

Conditions: Non-erosive Reflux Disease, Erosive Esophagitis
Interventions: BLI5100; Drug
Lead sponsor: Braintree Laboratories; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 60
States / cities: Huntsville, Alabama • Phoenix, Arizona • Tucson, Arizona + 48 more

Conditions: Gastro Esophageal Reflux
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 50 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Laryngopharyngeal Reflux, Hypertrophy of Lingual Tonsil
Interventions: dexlansoprazole; Drug
Lead sponsor: Advanced Center for Specialty Care; Other
Eligibility: 18 Years to 59 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obese Patients, Tobacco Use, Veterans, Family History of Esophageal Cancer, Barrett Esophagus
Interventions: Enrolled participants will complete Esocheck/Esoguard and diagnostic upper endoscopy.; Diagnostic Test
Lead sponsor: Louis Stokes VA Medical Center; Federal
Eligibility: 40 Years to 85 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: Rabeprazole ER, Ranitidine; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 4
States / cities: Moline, Illinois

Conditions: Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions: TIF Procedure; Procedure
Lead sponsor: EndoGastric Solutions; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 278 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 14
States / cities: Safford, Arizona • Tempe, Arizona • Englewood, Colorado + 11 more

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The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus

Prospective Evaluation of Symptom Resolution in Acid Versus Non-acid Reflux Disease Following Anti-reflux Surgery

Comparison of Laparoscopic Hill and Laparoscopic Nissen Anti-Reflux Procedures

Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux Disease

Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin

Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection

Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy

A Trial of Thickened Feeds to Treat Gastroesophageal Reflux in Children Admitted After Choking Spell

Does Omeprazole Decrease Intestinal Calcium Absorption?

Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn

The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis

The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)

Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease

Determination of Voiding Patterns of Children With Vesicoureteral Reflux

The BRILLIANT Study

Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)

Omega Cuff for GERD Feasibility Study

A Study to Evaluate the Long-Term Safety of BLI5100 in Patients With Gastroesophageal Reflux Disease

Efficacy Of Hiatal Closure For GERD

Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy

Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux

Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)

Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD)