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ClinicalTrials.gov public records Last synced Sep 11, 2026, 7:12 PM EDT

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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Genetic Predisposition to Cancer Clear all
Completed No phase listed Observational

Genetic Susceptibility to Oncogenic Viruses

NCT00341484
View directory record Official record
Conditions
Liver Neoplasms, HIV Infections
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
2,580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2007
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational

Adherence to Intensive Surveillance for Hereditary Breast Cancer

NCT00582803
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
25 Years and older · Female only
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2009 · Synced Sep 11, 2026, 7:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Detection of GEnetic Risk (EDGE)

NCT04746794
View directory record Official record
Conditions
Genetic Predisposition
Interventions
Population-level screening
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
20,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Billings, Montana • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility Antigens

NCT00001294
View directory record Official record
Conditions
Alcoholism, HIV Infection, Homosexuality, Kaposi's Sarcoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational

Registry of Mastectomy for Breast Cancer Risk Reduction

NCT00555503
View directory record Official record
Conditions
Quality of Life, Mastectomy, Breast Neoplasms, Genetic Predisposition to Disease, Adjustment Disorder
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 70 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2016 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational

Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer

NCT03688204
View directory record Official record
Conditions
Breast Cancer Risk
Interventions
Not listed
Lead sponsor
Ambry Genetics
Industry
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Burbank, California • Orange, California • Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Blood Markers of Early Pancreas Cancer

NCT03568630
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
1,250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Genetic Susceptibility to Lung Cancer in Never Smokers

NCT00597636
View directory record Official record
Conditions
Lung Cancer
Interventions
Questionaire, Blood sample
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

NCT06450171
View directory record Official record
Conditions
Cancer Predisposition Syndrome, Predisposition, Genetic
Interventions
GRAIL Galleri Test
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
22 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

NCT05587439
View directory record Official record
Conditions
Lung Cancer, Genetic Disease, Genetic Predisposition, Hereditary Diseases
Interventions
Data and Specimen Collection
Genetic
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

NCT04774445
View directory record Official record
Conditions
Cancer, Genetic Predisposition
Interventions
MyCancerGene
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

Familial Investigations of Childhood Cancer Predisposition

NCT03050268
View directory record Official record
Conditions
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML, BAP1 Tumor Predisposition Syndrome, Carney Complex, Choroid Plexus Carcinoma, Constitutional Mismatch Repair Deficiency Syndrome, Diamond-Blackfan Anemia, DICER1 Syndrome, Dyskeratosis Congenita, Emberger Syndrome, Familial Acute Myeloid Leukemia, Familial Adenomatous Polyposis, Fanconi Anemia, Familial Cancer, Familial Wilms Tumor, Familial Neuroblastoma, GIST, Hereditary Breast and Ovarian Cancer, Hereditary Paraganglioma-Pheochromocytoma Syndrome, Hodgkin Lymphoma, Juvenile Polyposis, Li-Fraumeni Syndrome, Lynch Syndrome, MDS, Melanoma Syndrome, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2, Neuroblastoma, Neurofibromatosis Type 1, Neurofibromatosis Type II, Nevoid Basal Cell Carcinoma Syndrome, Non Hodgkin Lymphoma, Noonan Syndrome and Other Rasopathy, Overgrowth Syndromes, Pancreatic Cancer, Peutz-Jeghers Syndrome, Pheochromocytoma/Paraganglioma, PTEN Hamartoma Tumor Syndrome, Retinoblastoma, Rhabdoid Tumor Predisposition Syndrome, Rhabdomyosarcoma, Rothmund-Thomson Syndrome, Tuberous Sclerosis, Von Hippel-Lindau Disease
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2037
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational

Outcomes of Education and Counseling for BRCA1 Testing

NCT00001468
View directory record Official record
Conditions
Breast Neoplasms, Ovarian Neoplasms
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 11, 2026, 7:12 PM EDT
Completed No phase listed Observational

Gene Analysis in Studying Susceptibility to Wilms Tumor

NCT01808079
View directory record Official record
Conditions
Recurrent Childhood Kidney Neoplasm, Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor, Stage III Kidney Wilms Tumor, Stage IV Kidney Wilms Tumor
Interventions
Laboratory Biomarker Analysis
Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Sep 11, 2026, 7:12 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

NCT05759143
View directory record Official record
Conditions
Genetic Predisposition to Disease, Genetic Predisposition
Interventions
Nest Platform
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

Outcomes of Health Care Transition for AYA With a Cancer Predisposition

NCT07456904
View directory record Official record
Conditions
Genetic Predisposition
Interventions
Readiness Assessment, Transition Outcomes Survey A, Transition Outcomes Survey B
Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Model for Genetic Susceptibility: Melanoma

NCT00591500
View directory record Official record
Conditions
Melanoma, Skin Cancer
Interventions
Questionnaire
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
4,082 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

NCT05849155
View directory record Official record
Conditions
Genetic Predisposition
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
10 Years to 24 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Active, not recruiting No phase listed Observational

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

NCT00001163
View directory record Official record
Conditions
Hereditary Neoplasms, Cancer, Genetic Predisposition to Cancer, Environment
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
5,201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1985
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting Phase 1 Interventional

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

NCT07264790
View directory record Official record
Conditions
Breast Reconstruction, Perfusion; Complications, High Risk for Breast Cancer, Genetic Predisposition
Interventions
Minoxidil, Hair mousse
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 11, 2026, 7:12 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)

NCT01447199
View directory record Official record
Conditions
Bladder Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer, Skin Cancer, Uterus Cancer
Interventions
Health and Diet Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort

NCT05929976
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Nutrition Aspect of Cancer, Microtia, Genetic Predisposition
Interventions
No intervention
Other
Lead sponsor
Columbia University
Other
Eligibility
3 Years to 18 Years
Enrollment
4,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting No phase listed Observational

Prostate Tissue BioBank

NCT06659614
View directory record Official record
Conditions
Prostate Cancer, Genetic Predisposition
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 11, 2026, 7:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)

NCT05926102
View directory record Official record
Conditions
Prostate Cancer
Interventions
Precision screening intervention, Usual care
Genetic · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 69 Years · Male only
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 11, 2026, 7:12 PM EDT